Preview

Neurology, Neuropsychiatry, Psychosomatics

Advanced search

Functional hemispheric specialization for verbal and visual perceptual processes in terms of blood flow velocity changes in unilateral brain lesions

https://doi.org/10.14412/2074-2711-2017-1-34-38

Full Text:

Abstract

Objective: to comparatively analyze the patterns of functional hemispheric specialization in patients with local brain tumor lesions and in healthy participants.

Patients and methods. 40 patients (20 men and 20 women) with local unilateral brain tumor lesions (astrocytomas, gliomas, metastases) aged 19–60 years (mean age, 33±9.2 years) were examined for functional hemispheric specialization for verbal and visual perceptual functions when performing cognitive tasks by functional transcranial Doppler ultrasonography. The findings were compared with those in 57 healthy individuals (mean age, 28±5.1 years). All the participants were right-handed.

Results. There was a more pronounced increase in blood flow velocity (BFV) while performing verbal cognitive tasks in the vessels of the left hemisphere (LH) and a more marked rise in that when fulfilling non-verbal cognitive tasks in the vessels of the right hemisphere (RH). The trends in the ratio of LH/RH BFV amplification when performing cognitive tasks were observed to be the same as previously observed in the healthy participants.

About the Authors

Yu. V. Mikadze
M.V. Lomonosov Moscow State University N.I. Pirogov Russian National Research Medical University
Russian Federation

Faculty of Psychology

Psychosocial Faculty

1, Leninskie Gory, Moscow 119997

1, Ostrovityanov St., Moscow 119977



M. D. Bogdanova
M.V. Lomonosov Moscow State University
Russian Federation

Faculty of Psychology

1, Leninskie Gory, Moscow 119997



S. M. Abuzaid
Acad. N.N. Burdenko Research Institute of Neurosurgery, Ministry of Health of Russia
Russian Federation
16, Fourth Tverskaya-Yamskaya St., Moscow 125047


A. R. Shakhnovich
Acad. N.N. Burdenko Research Institute of Neurosurgery, Ministry of Health of Russia
Russian Federation
16, Fourth Tverskaya-Yamskaya St., Moscow 125047


E. S. Lysenko
M.V. Lomonosov Moscow State University N.I. Pirogov Russian National Research Medical University
Russian Federation

Faculty of Psychology

Psychosocial Faculty

1, Leninskie Gory, Moscow 119997

1, Ostrovityanov St., Moscow 119977



References

1. Knecht S, Deppe M, Ebner A, et al. Noninvasive determination of language lateralization by functional transcranial Doppler sonography: a comparison with the Wada test. Stroke. 1998 Jan;29(1):82-6.

2. Knake S, Haag A, Hamer HM, et al. Language lateralization in patients with temporal lobe epilepsy: a comparison of functional transcranial Doppler sonography and the Wada test. Neuroimage. 2003 Jul;19(3):1228-32.

3. Witt JA, Prö mpler K, Maydych V, Helmstaedter C. Cross-validation of the Animation Description Paradigm applied to determine language dominance via functional transcranial Doppler sonography. Epilepsy & Behavior. 2010; Apr;17(4):611.

4. Schmidt P, Krings T, Willmes K, et al. Determination of cognitive hemispheric lateralization by «functional» transcranial Doppler cross-validated by functional MRI. Stroke. 1999; May;30(5):939-45.

5. Deppe M, Knecht S, Papke K, et al. Assessment of hemispheric language lateralization: a comparison between fMRI and fTCD. J Cereb Blood Flow Metab. 2000 Feb;20(2):263-8.

6. Szirmai I, Amrein I, Palvö lgyi L, et al. Correlation between blood flow velocity in the middle cerebral artery and EEG during cognitive effort. Brain Res Cogn Brain Res. 2005 Jun;24(1):33-40.

7. Duschek S, Schandry R. Functional transcranial Doppler sonography as a tool in psychophysiological research. Psychophysiology. 2003 May;40(3):436-54.

8. Stroobant N, Buijs D, Vingerhoets G, et al. Variation in brain lateralization during various language tasks: A functional transcranial Doppler study. Behav Brain Res. 2009 May 16;199(2):190-6. doi: 10.1016/j.bbr.2008.11.040. Epub 2008 Dec 3.

9. Vingerhoets G, Stroobant N. Lateralization of cerebral blood flow velocity changes during cognitive tasks. A simultaneous bilateral transcranial Doppler study. Stroke. 1999 Oct; 30(10):2152-8.

10. Flö el A, Buyx A, Breitenstein C, et al. Hemispheric lateralization of spatial attention in right- and left-hemispheric language dominance. Behav Brain Res. 2005 Mar 30;158(2):269- 75.

11. Illingworth S, Bishop DV. Atypical cerebral lateralisation in adults with compensated developmental dyslexia demonstrated using functional transcranial Doppler ultrasound. Brain Lang. 2009 Oct;111(1):61-5. doi:10.1016/j.bandl.2009.05.002. Epub 2009 Jun 13.

12. Strzelczyk A, Haag A, Raupach H. Prospective evaluation of a post-stroke epilepsy risk scale. J Neurol. 2010 Aug;257(8):1322-6. doi: 10.1007/s00415-010-5520-9. Epub 2010 Mar 23.

13. Janszky J, Jokeit H, Heinemann D. Epileptic activity influences the speech organization in medial temporal lobe epilepsy. Brain. 2003 Sep;126(Pt 9):2043-51. Epub 2003 Jun 23.

14. Schuepbach D, Boeker H, Duschek S, Hell D. Rapid cerebral hemodynamic modulation during mental planning and movement execution: evidence of time-locked relationship with complex behavior. Clin Neurophysiol. 2007 Oct;118(10):2254-62. Epub 2007 Sep 4.

15. Tiemeier H, Bakker SL, Hofman A, et al. Cerebral haemodynamics and depression in the elderly. J Neurol Neurosurg Psychiatry. 2002 Jul;73(1):34-9.

16. Silvestrini M, Troisi E, Matteis M. Involvement of the healthy hemisphere in recovery from aphasia and motor deficit in patients with cortical ischemic infarction: a transcranial Doppler study. Neurology. 1995 Oct;45(10):1815-20.

17. Лысенко ЕС. Влияние вида когнитивного задания на функциональную специализацию полушарий по данным изменений мозгового кровотока. Психологические исследования. 2016;9(47):7. [Lysenko ES. he influence of cognitive tasks on the functional specialization of the hemispheres according to the changes of cerebral bloodflow. Psikhologicheskie issledovaniya. 2016;9(47):7. (In Russ.)].

18. Микадзе ЮВ, Богданова МД, Лысенко ЕС и др. Оценка латерализации церебральной гемодинамики при выполнении вербальных мнестических заданий методом функциональной транскраниальной допплерографии. Экспериментальная психология. 2015;8(3):62–73. [Mikadze YuV, Bogdanova MD, Lysenko ES, et al. Assessment of the lateralization of cerebral hemodynamics when performing verbal memory tasks by the method of functional transcranial Doppler ultrasonography. Eksperimental'naya psikhologiya. 2015;8(3):62–73. (In Russ.)].


For citation:


Mikadze Y.V., Bogdanova M.D., Abuzaid S.M., Shakhnovich A.R., Lysenko E.S. Functional hemispheric specialization for verbal and visual perceptual processes in terms of blood flow velocity changes in unilateral brain lesions. Neurology, Neuropsychiatry, Psychosomatics. 2017;9(1):34-38. (In Russ.) https://doi.org/10.14412/2074-2711-2017-1-34-38

Views: 132


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2074-2711 (Print)
ISSN 2310-1342 (Online)