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Functional hemispheric specialization for verbal and visual perceptual processes in terms of blood flow velocity changes in unilateral brain lesions

https://doi.org/10.14412/2074-2711-2017-1-34-38

Abstract

Objective: to comparatively analyze the patterns of functional hemispheric specialization in patients with local brain tumor lesions and in healthy participants.

Patients and methods. 40 patients (20 men and 20 women) with local unilateral brain tumor lesions (astrocytomas, gliomas, metastases) aged 19–60 years (mean age, 33±9.2 years) were examined for functional hemispheric specialization for verbal and visual perceptual functions when performing cognitive tasks by functional transcranial Doppler ultrasonography. The findings were compared with those in 57 healthy individuals (mean age, 28±5.1 years). All the participants were right-handed.

Results. There was a more pronounced increase in blood flow velocity (BFV) while performing verbal cognitive tasks in the vessels of the left hemisphere (LH) and a more marked rise in that when fulfilling non-verbal cognitive tasks in the vessels of the right hemisphere (RH). The trends in the ratio of LH/RH BFV amplification when performing cognitive tasks were observed to be the same as previously observed in the healthy participants.

About the Authors

Yu. V. Mikadze
M.V. Lomonosov Moscow State University N.I. Pirogov Russian National Research Medical University
Russian Federation

Faculty of Psychology

Psychosocial Faculty

1, Leninskie Gory, Moscow 119997

1, Ostrovityanov St., Moscow 119977



M. D. Bogdanova
M.V. Lomonosov Moscow State University
Russian Federation

Faculty of Psychology

1, Leninskie Gory, Moscow 119997



S. M. Abuzaid
Acad. N.N. Burdenko Research Institute of Neurosurgery, Ministry of Health of Russia
Russian Federation
16, Fourth Tverskaya-Yamskaya St., Moscow 125047


A. R. Shakhnovich
Acad. N.N. Burdenko Research Institute of Neurosurgery, Ministry of Health of Russia
Russian Federation
16, Fourth Tverskaya-Yamskaya St., Moscow 125047


E. S. Lysenko
M.V. Lomonosov Moscow State University N.I. Pirogov Russian National Research Medical University
Russian Federation

Faculty of Psychology

Psychosocial Faculty

1, Leninskie Gory, Moscow 119997

1, Ostrovityanov St., Moscow 119977



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ISSN 2074-2711 (Print)
ISSN 2310-1342 (Online)