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Неврология, нейропсихиатрия, психосоматика

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Систематический анализ фундаментальных и клинических исследований этифоксина

https://doi.org/10.14412/2074-2711-2016-3-106-112

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Аннотация

Представлен систематический анализ экспериментальных и клинических исследований этифоксина. Анксиолитическое действие этифоксина осуществляется посредством, во-первых, модулирования активности ГАМК1-рецепторов и, во-вторых, модуляции метаболизма нейростероидов (которые сами по себе характеризуются анксиолитическими и нейропротекторными свойствами). Проанализированы также результаты клинических исследований этифоксина. Установлено, что, помимо анксиолитического эффекта, частично сохраняющегося даже после отмены терапии, этифоксин характеризуется анальгетическими, нейротрофическими и нейропротекторными свойствами.

Об авторах

И. Ю. Торшин
ФГБОУ ВО «Московский физико-технический институт», Долгопрудный, Россия 141700, Московская область, Долгопрудный, Институтский переулок, 9
Россия


О. А. Громова
ФГБОУ ВО «Ивановская государственная медицинская академия» Минздрава России, Иваново, Россия 153000, Иваново, Шереметевский пр., 8
Россия


В. А. Семенов
ФГБОУ ВО Кемеровская государственная медицинская академия Минздрава России, Кемерово, Россия 650056, Кемерово, ул. Ворошилова, 22А
Россия


Т. Р. Гришина
ФГБОУ ВО «Ивановская государственная медицинская академия» Минздрава России, Иваново, Россия 153000, Иваново, Шереметевский пр., 8
Россия


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Для цитирования:


Торшин И.Ю., Громова О.А., Семенов В.А., Гришина Т.Р. Систематический анализ фундаментальных и клинических исследований этифоксина. Неврология, нейропсихиатрия, психосоматика. 2016;8(3):106-112. https://doi.org/10.14412/2074-2711-2016-3-106-112

For citation:


Torshin I.Y., Gromova O.A., Semenov V.A., Grishina T.R. Systematic analysis of basic and clinical studies of etifoxine. Neurology, Neuropsychiatry, Psychosomatics. 2016;8(3):106-112. (In Russ.) https://doi.org/10.14412/2074-2711-2016-3-106-112

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ISSN 2074-2711 (Print)
ISSN 2310-1342 (Online)