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Cognitive impairment in COVID-19: associations, pathogenesis and treatment questions

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 Cognitive impairment (CI) can be neurological symptoms or complications of coronavirus disease 2019 (COVID-19). Among  the pathogenetic mechanisms, the neurotropicity of the SARS- CoV-2 virus, endothelial dysfunction, coagulopathy, thrombus  formation, systemic inflammatory reaction, the consequences of mechanical ventilation and drug sedation are considered. Treatment strategies  for COVID-19 patients with CI have not yet been developed. The following tactics of patient management is advisable: prevention of  re-infection, assessment and correction of the emotional state,  treatment of cardiovascular diseases. The possibilities of  vinpocetine in the treatment of CI after COVID-19 are discussed. 

About the Authors

V. A. Golovacheva
Department of Nervous System Diseases and Neurosurgery, N.V. Sklifosovsky Clinical Medicine Institute
Russian Federation

 8, Trubetskaya Str., Build. 2, Moscow 119991, Russia 

G. R. Tabeeva
Department of Nervous System Diseases and Neurosurgery, N.V. Sklifosovsky Clinical Medicine Institute
Russian Federation

 8, Trubetskaya Str., Build. 2, Moscow 119991, Russia 

I. V. Kuznetsov
University Hospital №3, I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia
Russian Federation

 8, Trubetskaya Str., Build. 2, Moscow 119991, Russia 


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For citations:

Golovacheva V.A., Tabeeva G.R., Kuznetsov I.V. Cognitive impairment in COVID-19: associations, pathogenesis and treatment questions. Neurology, Neuropsychiatry, Psychosomatics. 2021;13(2):123-129. (In Russ.)

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