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Effective neuroprotection and organ protection: activation of the endogenous mechanisms of sanogenesis

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The review sets out modern ideas about the mechanisms of action of gamma-aminobutyric acid (GABA) in the central nervous system and other organs and systems. Current experimental and clinical studies have shown that GABA has numerous effects: neuroprotective, antihypertensive, antidiabetic, antitumor, anti-inflammatory, antimicrobial, anti-allergic, hepatoprotective, nephroprotective and enteroprotective, and others, which are currently the subject for study by biologists, physiologists, and physicians. Synthetic GABA analogues are widely used in clinical practice. One of these drugs is aminophenylbutyric acid hydrochloride (Anvifen®) that has demonstrated high efficiency and safety in clinical practice.

About the Authors

R. G. Esin
Kazan State Medical Academy, Branch, Russian Medical Academy of Continuing Professional Education, Ministry of Health of Russia; Kazan (Volga) Federal University, Ministry of Education and Science of Russia
Russian Federation

Radiy Germanovich Esin.

11, Mushtari St., Kazan 420012; 18, Kremlevskaya St., Kazan 420008.

O. R. Esin
Kazan (Volga) Federal University, Ministry of Education and Science of Russia
Russian Federation
18, Kremlevskaya St., Kazan 420008.

A. R. Khakimova
Kazan State Medical Academy, Branch, Russian Medical Academy of Continuing Professional Education, Ministry of Health of Russia
Russian Federation

11, Mushtari St., Kazan 420012.


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46. Esin OR, Khairullin IK, Esin RG, Tokareva NV. Tension type headache: GABA-ergic drug anvifen efficacy. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. 2016;116(2): 58-61. (In Russ.).

47. Esin RG, Khairullin IK, Mukhametova ER, Esin OR. Persistent postural-perceptual dizziness. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. 2017;117(4):28-33 (In Russ.).

For citation:

Esin R.G., Esin O.R., Khakimova A.R. Effective neuroprotection and organ protection: activation of the endogenous mechanisms of sanogenesis. Neurology, Neuropsychiatry, Psychosomatics. 2020;12(3):123-127. (In Russ.)

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