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Impact of antiepileptic therapy on the course of affective disorders in women with epilepsy

https://doi.org/10.14412/2074-2711-2012-381

Abstract

The impact of antiepileptic drugs (AEDs) on affective disorders was analyzed in women with epilepsy. One hundred and one reproductive-aged epileptic patients with depressive and emotionally labile disorders were examined. Thirty-two (31.7%) and 64 (63.4%) took one and two AEDs, respectively; 5 (4.9%) patients did not take. New-generation AEDs were shown to have a more favorable profile of psychotropic effects than traditional ones. The positive psychotropic effects of lamotrigine in treating epilepsy in women with affective disorders are described.

About the Authors

E V Zheleznova

Department of Exogenous Organic Disorders and Epilepsy, Moscow Research Institute of Psychiatry, Ministry of Health and Social Development of the Russian Federation


I L Medvedev

Department of Exogenous Organic Disorders and Epilepsy, Moscow Research Institute of Psychiatry, Ministry of Health and Social Development of the Russian Federation


V V Kalinin

Department of Exogenous Organic Disorders and Epilepsy, Moscow Research Institute of Psychiatry, Ministry of Health and Social Development of the Russian Federation


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ISSN 2074-2711 (Print)
ISSN 2310-1342 (Online)