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Impact of stimulating cognitive-motor training on neuropsychological status and quality of life in patients with Parkinson's disease

https://doi.org/10.14412/2074-2711-2018-4-65-71

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Abstract

Motor and non-motor symptoms are identified in the clinical picture of Parkinson's disease (PD). Among its non-motor manifestations, cognitive impairment (CI) and emotional disorders play a special role in PD. It is important to search for new forms and methods of cognitive therapy in patients with PD.

Objective: to analyze neuropsychological status and quality of life (QOL) in PD patients and to evaluate the efficiency of personalized combination therapy with a stimulating cognitive motor training on computer and mobile devices in these patients.

Patients and methods. The investigation enrolled 112 patients with PD. A study group included 56 PD patients who received a cycle of combination therapy with cognitive-motor training on PC and mobile devices; a control group consisted of 56 PD patients who had only a drug therapy cycle. To evaluate neuropsychological status and QOL, the investigators used the Montreal Cognitive Assessment (MoCA), the McNair and Kahn memory self-evaluation scale, the Hospital Anxiety and Depression Scale (HADS), and the 36-Item Short Form Health Survey (SF-36) questionnaire.

Results and discussion. According to MoCA scores, CI of varying severity was diagnosed in the majority of patients: in 75 and 80.4% in the study and control groups, respectively. Depressive syndrome was detected in 53.6 and 64.3% in these groups, respectively. According to the SF-36, the physical status of patients had the greatest effect in reducing their QOL. There were treatment-induced statistically significant positive changes for the following domains: physical functioning (p<0.01), role-physical functioning (p<0.001), pain intensity (p<0.01), general health (p<0.01), role emotional (p<0.0001), and mental health (p<0.01).

Conclusion. The investigation has shown the efficiency of personalized therapy including stimulating cognitive-motor training on computer and mobile devices, which improves neuropsychological status and QOL in patients with PD.

About the Authors

Yu. N. Bykov
Irkutsk State Medical University, Ministry of Health of Russia
Russian Federation

Department of Nervous System Diseases.

1, Krasnoe Vosstanie St., Irkutsk 664003



T. B. Bender
Irkutsk State Medical University, Ministry of Health of Russia
Russian Federation

Department of Nervous System Diseases.

1, Krasnoe Vosstanie St., Irkutsk 664003



Yu. N. Vasiliev
Irkutsk State Medical University, Ministry of Health of Russia
Russian Federation

Department of Nervous System Diseases.

1, Krasnoe Vosstanie St., Irkutsk 664003



A. N. Kalyagin
Irkutsk State Medical University, Ministry of Health of Russia
Russian Federation

Department of Internal Propedeutics.

1, Krasnoe Vosstanie St., Irkutsk 664003



Т. М. Maksikova
Irkutsk State Medical University, Ministry of Health of Russia
Russian Federation

Department of Internal Propedeutics.

1, Krasnoe Vosstanie St., Irkutsk 664003



G. M. Orlova
Irkutsk State Medical University, Ministry of Health of Russia
Russian Federation

Department of Hospital Therapy.

1, Krasnoe Vosstanie St., Irkutsk 664003



N. M. Kozlova
Irkutsk State Medical University, Ministry of Health of Russia
Russian Federation

Department of Intermediate-Level Therapy.

1, Krasnoe Vosstanie St., Irkutsk 664003



O. V. Ryzhkova
Irkutsk State Medical University, Ministry of Health of Russia
Russian Federation

Department of Intermediate-Level Therapy.

1, Krasnoe Vosstanie St., Irkutsk 664003



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For citation:


Bykov Y.N., Bender T.B., Vasiliev Y.N., Kalyagin A.N., Maksikova Т.М., Orlova G.M., Kozlova N.M., Ryzhkova O.V. Impact of stimulating cognitive-motor training on neuropsychological status and quality of life in patients with Parkinson's disease. Neurology, Neuropsychiatry, Psychosomatics. 2018;10(4):65-71. (In Russ.) https://doi.org/10.14412/2074-2711-2018-4-65-71

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ISSN 2074-2711 (Print)
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