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Неврология, нейропсихиатрия, психосоматика

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Церебральная спорадическая неамилоидная микроангиопатия: патогенез, диагностика и особенности лечебной тактики

https://doi.org/10.14412/2074-2711-2018-4-13-22

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Аннотация

Статья посвящена самому частому варианту церебральной болезни мелких сосудов — спорадической церебральной неамилоидной микроангиопатии (СНАМА) в контексте острого и хронического нарушения мозгового кровообращения. Освещены актуальные вопросы невропатологии и патогенеза заболевания. Представлены современные нейровизуализационные маркеры СНАМА с подробным обсуждением лакунарных инфарктов, церебральных микроинфарктов и микрокровоизлияний. Рассмотрены клинические проявления хронической формы заболевания, в том числе когнитивные нарушения. Освещена проблема дифференциальной диагностики СНАМА и церебральной амилоидной ангиопатии. Обсуждены современные возможности минимизации рисков и повышения эффективности лечения данной категории пациентов.

Об авторах

А. А. Кулеш
ФГБОУВО «Пермский государственный медицинский университет им. акад. Е.А. Вагнера» Минздрава России
Россия

Алексей Александрович Кулеш

614990, Пермь, ул. Петропавловская, 26



В. Е. Дробаха
ФГБОУВО «Пермский государственный медицинский университет им. акад. Е.А. Вагнера» Минздрава России
Россия

614990, Пермь, ул. Петропавловская, 26



В. В. Шестаков
ФГБОУВО «Пермский государственный медицинский университет им. акад. Е.А. Вагнера» Минздрава России
Россия

614990, Пермь, ул. Петропавловская, 26



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Для цитирования:


Кулеш А.А., Дробаха В.Е., Шестаков В.В. Церебральная спорадическая неамилоидная микроангиопатия: патогенез, диагностика и особенности лечебной тактики. Неврология, нейропсихиатрия, психосоматика. 2018;10(4):13-22. https://doi.org/10.14412/2074-2711-2018-4-13-22

For citation:


Kulesh A.A., Drobakha V.E., Shestakov V.V. Sporadic cerebral non-amyloid microangiopathy: pathogenesis, diagnosis, and features of treatment policy. Neurology, Neuropsychiatry, Psychosomatics. 2018;10(4):13-22. (In Russ.) https://doi.org/10.14412/2074-2711-2018-4-13-22

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