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Role of melatonin in the treatment of depression

https://doi.org/10.14412/2074-2711-2011-153

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Abstract

Depression remains a serious problem despite the continuous stream of researches on the problems of affective disorders and the emergence of
new antidepressants. About 80% of inpatients with depression and 70% of outpatients with this condition complain of sleep disorders. There
are presently a few available hypotheses of the onset of depressive disorders. Prominent among them are neurotransmitter dysfunction
hypotheses and chronobiological concepts (the presence of altered circadian rhythms mediated by melatonin). There is currently a wide range
of drugs that are able to affect melatonin metabolism, amongst which there is agomelatine and fluvoxamine.

References

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For citation:


Kotova O.V., Kotova O.V. Role of melatonin in the treatment of depression. Neurology, Neuropsychiatry, Psychosomatics. 2011;3(2):85-88. (In Russ.) https://doi.org/10.14412/2074-2711-2011-153

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ISSN 2074-2711 (Print)
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