Current approaches to magnetic resonance imaging diagnosis of epileptogenic and associated lesions of the brain
https://doi.org/10.14412/2074-2711-2018-1S-4-11
Abstract
With the development of current neuroimaging techniques, their role in diagnosing epilepsy is becoming more significant and that is not only in identifying the disease that plays a key role in epileptogenesis, but also in assisting a clinician in the subsequent formulation of the diagnosis, in correcting drug therapy, and, in some cases, in addressing the issue of surgical treatment in the patient. The priority technique in this case is magnetic resonance imaging (MRI) that has high sensitivity and specificity in defining the location of minor and more major lesions of the brain structure and that includes a set of current sequences that can obtain important diagnostic information about the functional state of the brain. This article highlights the International League Against Epilepsy guidelines for MRI in patients with suspected epilepsy, assesses the use of and briefly characterizes both structural and functional pulse sequences that are most commonly included in the epileptological protocol. It considers major pathological processes and evaluates anatomical and functional changes in the brain structure, which play an important role in epileptogenesis.
About the Authors
E. M. PerepelovaRussian Federation
8/2, Trubetskaya St., Build. 2, Moscow 119991
V. A. Perepelov
Russian Federation
8/2, Trubetskaya St., Build. 2, Moscow 119991
2/1, Barrikadnaya St., Moscow 125993
M. S. Merkulova
Russian Federation
2/1, Barrikadnaya St., Moscow 125993
V. E. Sinitsyn
Russian Federation
2/1, Barrikadnaya St., Moscow 125993
3, Ivan’kovskoe Shosse, Moscow, 125367
References
1. Мухин КЮ, Петрухин АС, Миронов МБ. Эпилептические синдромы. Диагностика и терапия (Справочное руководство для врачей). Москва: Системные решения; 2008 [Mukhin KYu, Petrukhin AS, Mironov MB. Epilepticheskie sindromy. Diagnostika i terapiya (Spravochnoe rukovodstvo dlya vrachei) [Epileptic syndromes. Diagnosis and therapy (Reference guide for doctors)]. Moscow: Sistemnye resheniya; 2008 (In Russ.)].
2. Rü ber T, David B, Elger CE. MRI in epilepsy: clinical standard and evolution. Curr Opin Neurol. 2018 Apr;31(2):223-31. doi: 10.1097/WCO.0000000000000539
3. International League Against Epilepsy. URL: http://www.ilae.org/Visitors/About_ILAE/Index.cfm. Дата обращения – 16.01.2018.
4. Reiser MF, Hricak H, Knauth M. MRI in epilepsy. Textbook of epilepsy. Springer Science & Business Media; 2013.
5. Ринкк П. Магнитный резонанс в медицине. Москва: ГЭОТАР-Медиа; 2003 [Rinkk P. Magnitnyy rezonans v meditsine [Magnetic resonance in medicine]. Moscow: GEOTAR- Media; 2003 (In Russ.)].
6. Blumcke I, Thom M, Aronica E. International consensus classification of hippocampal sclerosis in temporal lobe epilepsy: a task force report from the ILAE Commission on Diagnostic Methods. Epilepsia. 2013;54:1315-29. doi: 10.1111/epi.12220
7. Shimogawa T, Morioka T, Sayama T, et al. The initial use of arterial spin labeling perfusion and diffusion-weighted MRI in the diagnosis of nonconvulsive partial status epileptics. Epilepsy Res. 2017;129:162-73. doi: 10.1016/j.eplepsyres.2016.12.008
8. Kwan BYM, Salehi F, Ohorodnyk P, et al. Usage of SWI acquired at 7T for quantitative evaluation of temporal lobe epilepsy patients with histopathological and clinical correlation: An initial pilot study. J Neurol Sci. 2016;369:82-7. doi: 10.1016/j.jns.2016.07.066
9. Tae WS, Ham BJ, Pyun SB, et al. Current Clinical Applications of Diffusion-Tensor Imaging in Neurological Disorders. J Clin Neurol. 2018;14:e6. doi: 10.3988/jcn.2018.14.2.129
10. Treit S, Steve T, Gross DW, Beaulieu C. High resolution in-vivo diffusion imaging of the human hippocampus. Neuroimage. 2018. doi: 10.1016/j.neuroimage.2018.01.034 [Epub ahead of print].
11. McLean MA, Koepp M, Woermann FG. Magnetic resonance spectroscopy in patients with epilepsy. In: Luders H, editor. Textbook of epilepsy Surgery. London: Informa Healthcare; 2008.
12. Willmann O, Wennberg R, May T, et al. The role of 1H magnetic resonance spectroscopy in pre-operative evaluation for epilepsy surgery. A meta-analysis. Epilepsy Res. 2006;71:149- 58. doi: 10.1016/j.eplepsyres.2006.06.004
13. Urbach H. High-Field Magnetic Resonance Imaging for Epilepsy. Neuroimaging Clin N Am. 2012 May;22(2):173-89, ix-x. doi: 10.1016/j.nic.2012.02.008. Epub 2012 Mar 30.
14. Oner AYu, Eryurt B, Ucar M, et al. pASL versus DSC perfusion MRI in lateralizing temporal lobe epilepsy. Acta Radiologica. 2015;56(4):477-81. doi: 10.1177/0284185114531128
15. Kim BS, Lee ST, Yun TJ, et al. Capability of arterial spin labeling MR imaging in localizing seizure focus in clinical seizure activity. Eur J Radiol. 2016;85(7):1295-303. doi: 10.1016/j.ejrad.2016.04.015
16. Szaflarski JP, Gloss D, Binder JR, et al. Practice guideline summary: Use of fMRI in the presurgical evaluation of patients with epilepsy. Neurology. 2017;88(4):395-402. doi: 10.1212/WNL.0000000000003532
17. Engel J Jr, Pedley TA, Aicardi J, et al. Epilepsy: A Comprehensive Textbook. Lippincott Williams & Wilkins; 2008.
18. Friedman E. Epilepsy Imaging in Adults: Getting It Right. Neuroradiology/Head and Neck Imaging. 2014;203:1093-103. doi: 10.2214/AJR.13.12035
19. Kokkinos V, Kallifatidis A, Kapsalaki EZ, et al. Thin isotropic FLAIR MR images at 1.5T increase the yield of focal cortical dysplasia transmantle sign detection in frontal lobe epilepsy. Epilepsy Res. 2017 May;132:1-7. doi: 10.1016/j.eplepsyres.2017.02.018
20. Williams JA, Bede P, Doherty CP. An exploration of the spectrum of peri-ictal MRI change; A comprehensive literature review, 2017. Seizure. 2017;50:19-32. doi: 10.1016/j.seizure.2017.05.005
21. Ladino LD, Balaguera P, Rascovsky S, et al. Clinical Benefit of 3 Tesla Magnetic Resonance Imaging Rescanning in Patients With Focal Epilepsy and Negative 1.5 Tesla Magnetic Resonance Imaging. Rev Invest Clin. 2016 May-Jun;68(3):112-8.
22. Авакян ГН. Вопросы современной эпилептологии. Эпилепсия и пароксизмальные состояния. 2015;7(4):16- 21 [Avakyan GN. Issues of modern epileptology. Epilepsiya i Paroksizmal'nye Sostoyaniya. 2015;7(4):16-21 (In Russ.)].
23. Авакян ГН, Блинов ДВ, Лебедева АВ и др. Классификация эпилепсии Международной противоэпилептической лиги: пересмотр и обновление 2017 года. Эпилепсия и пароксизмальные состояния. 2017;9(1):6-25 [Avakyan GN, Blinov DV, Lebedeva AV, et al. Classification of Epilepsy of the International Antiepileptic League: revision and update of 2017. Epilepsiya i Paroksizmal'nye Sostoyaniya. 2017;9(1):6-25 (In Russ.)].
24. Craven I, Griffiths PD, Hoggard N. Magnetic resonance imaging of epilepsy at 3 Tesla. Clin Radiol. 2011 Mar;66(3):278-86. doi: 10.1016/j.crad.2010.10.010
25. Rodrigo S, Oppenheim C, Leclerc X, et al. Structural MRI in adult partial epilepsy. Neurochirurgie. 2008 May;54(3):191-6. doi: 10.1016/j.neuchi.2008.02.045
Review
For citations:
Perepelova EM, Perepelov VA, Merkulova MS, Sinitsyn VE. Current approaches to magnetic resonance imaging diagnosis of epileptogenic and associated lesions of the brain. Nevrologiya, neiropsikhiatriya, psikhosomatika = Neurology, Neuropsychiatry, Psychosomatics. 2018;10(1S):4-11. (In Russ.) https://doi.org/10.14412/2074-2711-2018-1S-4-11