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Current approaches to magnetic resonance imaging diagnosis of epileptogenic and associated lesions of the brain

https://doi.org/10.14412/2074-2711-2018-1S-4-11

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Abstract

With the development of current neuroimaging techniques, their role in diagnosing epilepsy is becoming more significant and that is not only in identifying the disease that plays a key role in  epileptogenesis, but also in assisting a clinician in the subsequent  formulation of the diagnosis, in correcting drug therapy, and, in  some cases, in addressing the issue of surgical treatment in the  patient. The priority technique in this case is magnetic resonance  imaging (MRI) that has high sensitivity and specificity in defining the  location of minor and more major lesions of the brain structure  and that includes a set of current sequences that can obtain  important diagnostic information about the functional state of the  brain. This article highlights the International League Against  Epilepsy guidelines for MRI in patients with suspected epilepsy,  assesses the use of and briefly characterizes both structural and  functional pulse sequences that are most commonly included in the  epileptological protocol. It considers major pathological processes  and evaluates anatomical and functional changes in the brain  structure, which play an important role in epileptogenesis.

About the Authors

E. M. Perepelova
I.M. Sechenov First Medical State University (Sechenov University), Ministry of Health of Russia
Russian Federation
8/2, Trubetskaya St., Build. 2, Moscow 119991


V. A. Perepelov
I.M. Sechenov First Medical State University (Sechenov University), Ministry of Health of Russia Russian Medical Academy of Postgraduate Education, Ministry of Health of Russia
Russian Federation

8/2, Trubetskaya St., Build. 2, Moscow 119991

2/1, Barrikadnaya St., Moscow 125993



M. S. Merkulova
Russian Medical Academy of Postgraduate Education, Ministry of Health of Russia
Russian Federation
2/1, Barrikadnaya St., Moscow 125993


V. E. Sinitsyn
Russian Medical Academy of Postgraduate Education, Ministry of Health of Russia Federal Treatment and Rehabilitation Center, Ministry of Health of Russia
Russian Federation

2/1, Barrikadnaya St., Moscow 125993

3, Ivan’kovskoe Shosse, Moscow, 125367



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For citation:


Perepelova E.M., Perepelov V.A., Merkulova M.S., Sinitsyn V.E. Current approaches to magnetic resonance imaging diagnosis of epileptogenic and associated lesions of the brain. Neurology, Neuropsychiatry, Psychosomatics. 2018;10(1S):4-11. (In Russ.) https://doi.org/10.14412/2074-2711-2018-1S-4-11

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ISSN 2074-2711 (Print)
ISSN 2310-1342 (Online)