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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">nnp</journal-id><journal-title-group><journal-title xml:lang="en">Neurology, Neuropsychiatry, Psychosomatics</journal-title><trans-title-group xml:lang="ru"><trans-title>Неврология, нейропсихиатрия, психосоматика</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-2711</issn><issn pub-type="epub">2310-1342</issn><publisher><publisher-name>"IMA-Press", LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/2074-2711-2018-1S-4-11</article-id><article-id custom-type="elpub" pub-id-type="custom">nnp-902</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LECTURES</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЛЕКЦИЯ</subject></subj-group></article-categories><title-group><article-title>Current approaches to magnetic resonance imaging diagnosis of epileptogenic and associated lesions of the brain</article-title><trans-title-group xml:lang="ru"><trans-title>Современные подходы к диагностике с помощью магнитно-резонансной томографии эпилептогенных и сопряженных с ними поражений головного мозга</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Перепелова</surname><given-names>Е. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Perepelova</surname><given-names>E. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119991, Москва, ул. Трубецкая, 8, стр. 2</p></bio><bio xml:lang="en"><p>8/2, Trubetskaya St., Build. 2, Moscow 119991</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Перепелов</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Perepelov</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119991, Москва, ул. Трубецкая, 8, стр. 2</p><p>125993, Москва, ул. Баррикадная, 2/1</p></bio><bio xml:lang="en"><p>8/2, Trubetskaya St., Build. 2, Moscow 119991</p><p>2/1, Barrikadnaya St., Moscow 125993</p></bio><email xlink:type="simple">vsevolod.perepelov@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Меркулова</surname><given-names>М. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Merkulova</surname><given-names>M. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>125993, Москва, ул. Баррикадная, 2/1</p></bio><bio xml:lang="en"><p>2/1, Barrikadnaya St., Moscow 125993</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Синицын</surname><given-names>В. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Sinitsyn</surname><given-names>V. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>125993, Москва, ул. Баррикадная, 2/1</p><p>125367, Москва, Иваньковское шоссе, 3</p></bio><bio xml:lang="en"><p>2/1, Barrikadnaya St., Moscow 125993</p><p>3, Ivan’kovskoe Shosse, Moscow, 125367</p></bio><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.M. Sechenov First Medical State University (Sechenov University), Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский университет)&#13;
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ГБОУ ДПО «Российская медицинская академия последипломного образования» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.M. Sechenov First Medical State University (Sechenov University), Ministry of Health of Russia&#13;
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Russian Medical Academy of Postgraduate Education, Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ГБОУ ДПО «Российская медицинская академия последипломного образования» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Medical Academy of Postgraduate Education, Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ГБОУ ДПО «Российская медицинская академия последипломного образования» Минздрава России&#13;
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ФГАУ «Лечебно-реабилитационный центр» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Medical Academy of Postgraduate Education, Ministry of Health of Russia&#13;
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Federal Treatment and Rehabilitation Center, Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>17</day><month>07</month><year>2018</year></pub-date><volume>10</volume><issue>1S</issue><issue-title>СПЕЦВЫПУСК: ЭПИЛЕПСИЯ</issue-title><fpage>4</fpage><lpage>11</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Perepelova E.M., Perepelov V.A., Merkulova M.S., Sinitsyn V.E., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Перепелова Е.М., Перепелов В.А., Меркулова М.С., Синицын В.Е.</copyright-holder><copyright-holder xml:lang="en">Perepelova E.M., Perepelov V.A., Merkulova M.S., Sinitsyn V.E.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://nnp.ima-press.net/nnp/article/view/902">https://nnp.ima-press.net/nnp/article/view/902</self-uri><abstract><p>With the development of current neuroimaging techniques, their role in diagnosing epilepsy is becoming more significant and that is not only in identifying the disease that plays a key role in  epileptogenesis, but also in assisting a clinician in the subsequent  formulation of the diagnosis, in correcting drug therapy, and, in  some cases, in addressing the issue of surgical treatment in the  patient. The priority technique in this case is magnetic resonance  imaging (MRI) that has high sensitivity and specificity in defining the  location of minor and more major lesions of the brain structure  and that includes a set of current sequences that can obtain  important diagnostic information about the functional state of the  brain. This article highlights the International League Against  Epilepsy guidelines for MRI in patients with suspected epilepsy,  assesses the use of and briefly characterizes both structural and  functional pulse sequences that are most commonly included in the  epileptological protocol. It considers major pathological processes  and evaluates anatomical and functional changes in the brain  structure, which play an important role in epileptogenesis.</p></abstract><trans-abstract xml:lang="ru"><p>С развитием современных методов нейровизуализации их роль в диагностике эпилепсии становится все более значительной и заключается не только в выявлении патологии,  играющей ключевую роль в эпилептогенезе, но и в содействии врачу-клиницисту в последующей формулировке диагноза, коррекции медикаментозной терапии, а в некоторых  случаях – в решении вопроса о хирургическом лечении пациента. Приоритетной методикой  в данном случае является магнитно-резонансная томография (МРТ), обладающая высокой  чувствительностью и специфичностью в отношении локализации мелких и более крупных  нарушений структуры головного мозга, а также включающая набор современных  последовательностей, позволяющих получать важную диагностическую информацию о  функциональном состоянии головного мозга. В настоящей статье освещены рекомендации  Международной противоэпилептической лиги по проведению МРТ у пациентов с  подозрением на эпилепсию, оценено назначение и дана краткая характеристика как  структурных, так и функциональных импульсных последовательностей, наиболее часто  включаемых в эпилептологический протокол. Рассмотрены основные патологические  процессы и дана оценка анатомо-функциональных изменений структуры головного мозга,  играющих важную роль в эпилептогенезе.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>эпилепсия</kwd><kwd>магнитно-резонансная томография</kwd><kwd>эпилептологический протокол</kwd><kwd>современные нейровизуализационные методики</kwd></kwd-group><kwd-group xml:lang="en"><kwd>epilepsy</kwd><kwd>magnetic resonance imaging</kwd><kwd>epileptologic protocol</kwd><kwd>current neuroimaging techniques</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Мухин КЮ, Петрухин АС, Миронов МБ. Эпилептические синдромы. Диагностика и терапия (Справочное руководство для врачей). Москва: Системные решения; 2008 [Mukhin KYu, Petrukhin AS, Mironov MB. Epilepticheskie sindromy. Diagnostika i terapiya (Spravochnoe rukovodstvo dlya vrachei) [Epileptic syndromes. 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