Preview

Neurology, Neuropsychiatry, Psychosomatics

Advanced search

Neuromyelitis optica spectrum disorders in pediatric patients

https://doi.org/10.14412/2074-2711-2018-1-60-64

Full Text:

Abstract

Neuromyelitis optica spectrum disorders (NMOSDs) is an inflammatory demyelinating disease of the central nervous system with a selective injury of the optic nerves and spinal cord. The formation of neuromyelitis optica ((NMO)-IgG autoantibodies against the cell membrane water channel protein aquaporin 4 (AQP4) underlies the pathogenesis of the disease. The article describes the clinical presentation of the disease in pediatric patients followed up by the authors. It presents the criteria for diagnosing NMOSDs and their therapy regimens.

About the Authors

Yu. V. Tokareva
M.F. Vladimirsky Moscow Regional Research Clinical Institute
Russian Federation

61/2, Shchepkin St., Moscow 129110



A. S. Kotov
M.F. Vladimirsky Moscow Regional Research Clinical Institute
Russian Federation

61/2, Shchepkin St., Moscow 129110



M. V. Panteleeva
M.F. Vladimirsky Moscow Regional Research Clinical Institute
Russian Federation

61/2, Shchepkin St., Moscow 129110



M. S. Bunak
M.F. Vladimirsky Moscow Regional Research Clinical Institute
Russian Federation

61/2, Shchepkin St., Moscow 129110



References

1. Oh J, Levy M. Neuromyelitis optica: an antibody-mediated disorder of the central nervous system. Neurol Res Int. 2012;2012:460825. doi: 10.1155/2012/460825. Epub 2012 Jan 29.

2. Wingerchuk DM, Lennon VA, Lucchinetti CF, et al. The spectrum of neuromyelitis optica. Lancet Neurol. 2007 Sep;6(9):805-15.

3. Луцик ВН, Котов АС, Борисова МН и др. Оптикомиелит Девика у ребенка. Неврологический журнал. 2017;(4):205-10. [Lutsik VN, Kotov AS, Borisova MN, et al. Devic’s neuromyelitis optica in child. Nevrologicheskii zhurnal. 2017;(4):205-10. (In Russ.)].

4. Banwell B, Tenembaum S, Lennon VA, et al. Neuromyelitis optica-IgG in childhood inflammatory demyelinating CNS disorders. Neurology. 2008 Jan 29;70(5):344-52. Epub 2007 Dec 19.

5. Yuksel D, Senbil N, Yilmaz D, et al. Devic’s neuromyelitis optica in an infant case. J Child Neurol. 2007 Sep;22(9):1143-6.

6. Cabrera-Gomez JA, Kurtzke JF, GonzalezQuevedo A, Lara-Rodriguez R. An epidemiological study of neuromyelitis optica in Cuba. J Neurol. 2009 Jan;256(1):35-44. doi: 10.1007/ s00415-009-0009-0. Epub 2009 Feb 9.

7. Etemadifar M, Nasr Z, Khalili B, Taherioun M, Vosoughi R. Epidemiology of Neuromyelitis Optica in the World: A Systematic Review and Meta-Analysis. Mult Scler Int. 2015;2015: 174720. doi: 10.1155/2015/174720. Epub 2015 Apr 20.

8. Trebst C, Jarius S, Berthele A, et al. Update on the diagnosis and treatment of neuromyelitis optica: Recommendations of the Neuromyelitis Optica Study Group (NEMOS). J Neurol. 2014 Jan;261(1):1-16. doi: 10.1007/s00415-013-7169-7. Epub 2013 Nov 23.

9. Eikelenboom MJ, Killestein J, Uitdehaag BM, Polman CH. Opticospinal multiple sclerosis: a pathogenetically distinct form? Mult Scler. 2004 Jun;10(3):334-5.

10. Lennon VA, Kryzer TJ, Pittock SJ, et al. IgG-merker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel. J Exp Med. 2005 Aug 15;202(4):473-7. Epub 2005 Aug 8.

11. Satoh J, Obayashi S, Misawa T, et al. Neuromyelitis optica/Devic’s disease: gene expression profiling of brain lesion. Neuropathology. 2008 Dec;28(6):561-76. doi: 10.1111/ j.1440-1789.2008.00915.x. Epub 2008 Apr 7.

12. Matiello M, Jacob A, Wingerchuk DM, Weinshenker BG. Neuromyelitis optica. Curr Opin Neurol. 2007 Jun;20(3):255-60. doi: 10.1097/WCO.0b013e32814f1c6b

13. Koga M, Takahashi T, Kawai M, et al. A serological analysis of viral and bacterial infections associated with neuromyelitis optica. J Neurol Sci. 2011 Jan 15;300(1-2):19-22. doi: 10.1016/j.jns.2010.10.013. Epub 2010 Nov 5.

14. Pandit L. Neuromyelitis optica spectrum disorders: An update. Ann Indian Acad Neurol. 2015;18(Suppl S1):11-5.

15. Wingerchuk DM, Banwell B, Bennett JL, et al. International consensus diagnostic criteria for neuromyelitis optica spectrum disorders. Neurology. 2015 Jul 14;85(2):177-89. doi: 10.1212/WNL.0000000000001729. Epub 2015 Jun 19.

16. Mariotto S, Ferrari S, Monaco S. Clinical spectrum and IgG subclass analysis of anti myelin oligodendrocyte glycoprotein antibody associated syndromes: a multicenter study. J Neurol. 2017 Dec;264(12):2420-30. doi: 10.1007/s00415-017-8635-4. Epub 2017 Oct 23.

17. Coutinho AE, Chapman KE. The antiinflammatory and immunosuppressive effects of glucocorticoids, recent developments and mechanistic insights. Mol Cell Endocrinol. 2011 Mar 15;335(1):2-13. doi: 10.1016/j.mce.2010. 04.005. Epub 2010 Apr 14.

18. Котов АС, Андрюхина ОМ, Матюк ЮВ и др. Оптический неврит и миелит у подростка: оптикомиелит Девика или рассеянный склероз? Неврологический журнал. 2015;(6): 37-42. [Kotov AS, Andryukhina OM, Matyuk YuV, et al. Optic neuritis and myelitis in teenager: Devic’s neuromyelitis optica or multiple sclerosis? Nevrologicheskii zhurnal. 2015;(6): 37-42. (In Russ.)].


For citation:


Tokareva Y.V., Kotov A.S., Panteleeva M.V., Bunak M.S. Neuromyelitis optica spectrum disorders in pediatric patients. Neurology, Neuropsychiatry, Psychosomatics. 2018;10(1):60-64. (In Russ.) https://doi.org/10.14412/2074-2711-2018-1-60-64

Views: 192


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2074-2711 (Print)
ISSN 2310-1342 (Online)