Neuromyelitis optica spectrum disorders in pediatric patients
Abstract
Neuromyelitis optica spectrum disorders (NMOSDs) is an inflammatory demyelinating disease of the central nervous system with a selective injury of the optic nerves and spinal cord. The formation of neuromyelitis optica ((NMO)-IgG autoantibodies against the cell membrane water channel protein aquaporin 4 (AQP4) underlies the pathogenesis of the disease. The article describes the clinical presentation of the disease in pediatric patients followed up by the authors. It presents the criteria for diagnosing NMOSDs and their therapy regimens.
About the Authors
Yu. V. Tokareva
M.F. Vladimirsky Moscow Regional Research Clinical Institute
Russian Federation
Russian Federation
61/2, Shchepkin St., Moscow 129110
A. S. Kotov
M.F. Vladimirsky Moscow Regional Research Clinical Institute
Russian Federation
Russian Federation
61/2, Shchepkin St., Moscow 129110
M. V. Panteleeva
M.F. Vladimirsky Moscow Regional Research Clinical Institute
Russian Federation
Russian Federation
61/2, Shchepkin St., Moscow 129110
M. S. Bunak
M.F. Vladimirsky Moscow Regional Research Clinical Institute
Russian Federation
Russian Federation
61/2, Shchepkin St., Moscow 129110
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Review
For citations:
Tokareva Yu.V., Kotov A.S., Panteleeva M.V., Bunak M.S. Neuromyelitis optica spectrum disorders in pediatric patients. Neurology, Neuropsychiatry, Psychosomatics. 2018;10(1):60-64. (In Russ.) https://doi.org/10.14412/2074-2711-2018-1-60-64
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