nnpNeurology, Neuropsychiatry, PsychosomaticsНеврология, нейропсихиатрия, психосоматика2074-27112310-1342"IMA-Press", LLC10.14412/2074-2711-2018-1-60-64nnp-832Research ArticleCLINICAL OBSERVATIONSКЛИНИЧЕСКИЕ НАБЛЮДЕНИЯNeuromyelitis optica spectrum disorders in pediatric patientsРасстройства из спектра оптиконевромиелита у пациентов детского возрастаТокареваЮ. В.TokarevaYu. V.

129110, Москва, ул. Щепкина, 61/2

61/2, Shchepkin St., Moscow 129110

КотовА. С.KotovA. S.

129110, Москва, ул. Щепкина, 61/2

61/2, Shchepkin St., Moscow 129110

alex-013@yandex.ruПантелееваМ. В.PanteleevaM. V.

129110, Москва, ул. Щепкина, 61/2

61/2, Shchepkin St., Moscow 129110

БунакМ. С.BunakM. S.

129110, Москва, ул. Щепкина, 61/2

61/2, Shchepkin St., Moscow 129110

ГБУЗ МО «Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского»РоссияM.F. Vladimirsky Moscow Regional Research Clinical InstituteRussian Federation2018020420181016064Copyright © Tokareva Y.V., Kotov A.S., Panteleeva M.V., Bunak M.S., 20182018Токарева Ю.В., Котов А.С., Пантелеева М.В., Бунак М.С.Tokareva Y.V., Kotov A.S., Panteleeva M.V., Bunak M.S.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://nnp.ima-press.net/nnp/article/view/832

Neuromyelitis optica spectrum disorders (NMOSDs) is an inflammatory demyelinating disease of the central nervous system with a selective injury of the optic nerves and spinal cord. The formation of neuromyelitis optica ((NMO)-IgG autoantibodies against the cell membrane water channel protein aquaporin 4 (AQP4) underlies the pathogenesis of the disease. The article describes the clinical presentation of the disease in pediatric patients followed up by the authors. It presents the criteria for diagnosing NMOSDs and their therapy regimens.

Расстройства из спектра оптиконевромиелита (ОНМ – neuromyelitis optica spectrum disorders, NMOSD) – воспалительное демиелинизирующее заболевание ЦНС с избирательным поражением зрительных нервов и спинного мозга. В основе патогенеза заболевания лежит образование аутоантител NMO-IgG к белку водопроводящих каналов клеточных мембран аквапорину 4 (AQP4). В статье описана клиническая картина заболевания у пациентов детского возраста, находившихся под наблюдением авторов. Представлены критерии диагностики расстройств из спектра ОНМ и схемы их терапии.

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The authors declare that there are no conflicts of interest present.