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Chronic pain-associated cognitive impairment

https://doi.org/10.14412/2074-2711-2017-3-4-9

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Abstract

The current understanding of the mechanisms of chronic pain (CP) implies the mandatory consideration of not only its properly sensory proper, but also emotional, affective, and cognitive aspects. Cognitive impairment (CI) in patients with different chronic pain syndromes makes a substantial contribution to impairment in daily functioning. In recent years, the ideas about the mechanisms of CI and emotional disorders in this patient group have been considerably extended due to functional neuroimaging investigations. Experimental studies demonstrate that there are changes in both the structures related to pain control and the brain regions responsible for key cognitive functions. These data expand the views of mechanisms for polymorphic clinical symptoms in patients with CP and justify the feasibility of using psychological methods in its combined therapy.

About the Authors

N. N. Koberskaya
I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia
Russian Federation

11, Rossolimo St., Moscow 119021

Department of Nervous System Diseases and Neurosurgery



G. R. Tabeeva
I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia
Russian Federation

11, Rossolimo St., Moscow 119021

Department of Nervous System Diseases and Neurosurgery



References

1. Melzack R, Casey KL. Sensory, motivation and central control determinants of pain: a new conceptual model. In: Kenshalo D, editor. The skin senses. Springfield, Illinois: Charles C. Thomas; 1968. P. 423-9.

2. Moriarty O, McGuire BE, Finn DP. The effect of pain on cognitive function: a review of clinical and preclinical research. Prog Neurobiol. 2011 Mar;93(3):385-404. doi: 10.1016/j.pneurobio.2011.01.002. Epub 2011 Jan 7.

3. Landro NI, Fors EA, Vepenstad LL, et al. The extent of neurocognitive dysfunction in a multidisciplinary pain center population. Is there a relation between reported and tested neuropsychological functioning? Pain. 2013 Jul;154(7):972-7. doi: 10.1016/j.pain.2013.01.013. Epub 2013 Feb 8.

4. Merskey H, Bogduk N. IASP Task Force on Taxonomy, Classification of Chronic Pain; Part III: Pain Terms, a Current List with Definitions and Notes on Usage. Seattle: IASP Press; 1994.

5. Loggia ML, Mogil JS, Bushnell MC. Empathy hurts: compassion for another increases both sensory and affective components of pain perception. Pain. 2008 May;136(1-2):168-76. Epub 2007 Sep 5.

6. Colucci F, Fornasari D, Pergolizzi J, Romualdi P. From acute to chronic pain: tapendalol in the progressive stages of this disease entity. Eur Rev Med Pharmacol Sci. 2017 Apr; 21(7):1672-1683.

7. Hö lzel BK, Carmody J, Vangel M, et al. Mindfulness practice leads to increases in regional brain gray matter density. Psychiatry Res. 2011 Jan 30;191(1):36-43. doi: 10.1016/j.pscychresns.2010.08.006. Epub 2010 Nov 10.

8. Apkarian AV, Hashmi JA, Baliki MN. Pain and the brain: specificity and plasticity of the brain in clinical chronic pain. Pain. 2011 Mar;152(3 Suppl):S49-64. doi: 10.1016/j.pain.2010.11.010. Epub 2010 Dec 13.

9. Mutso AA, Radzicki D, Baliki MN, et al. Abnormalities in hippocampal functioning with persistent pain. J Neurosci. 2012 Apr 25;32(17): 5747-56. doi: 10.1523/JNEUROSCI.0587-12.2012.

10. Weiner DK, Rudy TE, Morrow L, et al. The relationship between pain, neuropsychological performance, and physical function in community-dwelling older adults with chronic low back pain. Pain Med. 2006 Jan-Feb;7(1): 60-70.

11. Eccleston C. Chronic pain and distraction: An experimental investigation into the role of sustained and shifting attention in the processing of chronic persistent pain. Behav Res Ther. 1995 May;33(4):391-405.

12. Valet M, Gü ndel H, Sprenger T, et al. Patients with pain disorder show gray-matter loss in pain-processing structures: a voxel-based morphometric study. Psychosom Med. 2009 Jan;71(1):49-56. doi: 10.1097/PSY.0b013e31818d1e02. Epub 2008 Dec 10.

13. Белова АН, Балдова СН, Хрулев СЕ. Нейродегенеративные свойства хронической боли и депрессии. Современные проблемы науки и образования. 2013;(3):42-53. [Belova AN, Baldova SN, Khrulev SE. Neurodegenerative properties of chronic pain and depression. Sovremennye problemy nauki i obrazovaniya. 2013;(3):42-53. (In Russ.)].

14. Lebel C, Gee M, Camicioli R, et al. Diffusion tensor imaging of white matter tract evolution over the lifespan. Neuroimage. 2012 Mar;60(1):340-52. doi: 10.1016/j.neuroimage.2011.11.094. Epub 2011 Dec 8.

15. Head D, Rodrigue KM, Kennedy KM, Raz N. Neuroanatomical and cognitive mediators of age-related differences in episodic memory. Neuropsychology. 2008 Jul;22(4): 491-507. doi: 10.1037/0894-4105.22.4.491.

16. Oosterman JM, De Vries K, Dijkerman HC, et al. Exploring the relationship between cognition and pain experience in residents of homes for the elderly. Int Psychogeriatr. 2009 Feb;21(1): 157-63. doi: 10.1017/S1041610208007941. Epub 2008 Nov 20.

17. Oosterman JM, Gibson SJ, Pulles WL, Veldhuijzen DS. On the moderating role of age in the relationship between pain and cognition. Eur J Pain. 2013 May;17(5):735-41. doi: 10.1002/j.1532-2149.2012.00235.x. Epub 2012 Nov 7.

18. Oosterman JM, Derksen LC, van Wijck AJ, et al. Executive and attention functions in chronic pain: does performance decrease with increasing task load? Pain Res Manag. 2012 May-Jun;17(3):159-65.

19. Smallwood RF, Laird AR, Ramage AE, et al. Structural brain abnormalities and chronic pain: a quantitative meta-analysis of gray matter volume. J Pain. 2013 Jul;14(7):663-75. doi: 10.1016/j.jpain.2013.03.001. Epub 2013 May 17.

20. Luerding R, Weigand T, Bogdahn U, Schmidt-Wilcke T. Working memory performance is correlated with local brain morphology in the medial frontal and anterior cingulate cortex in fibromyalgia patients: structural correlates of pain-cognition interaction. Brain. 2008 Dec; 131(Pt 12):3222-31.

21. Povedano M, Gascon J, Galvez R, et al. Cognitive function impairment in patients with neuropathic pain under standard conditions of care. J Pain Symptom Manage. 2007 Jan;33(1): 78-89.

22. Nyberg L, Lö vden M, Riklund K, et al. Memory aging and brain maintenance. Trends Cogn Sci. 2012 May;16(5):292-305. doi: 10.1016/j.tics.2012.04.005.

23. Daselaar SM, Veltman DJ, Rombouts SA, et al. Neuroanatomical correlates of episodic encoding and retrieval in young and elderly subjects. Brain. 2003 Jan;126(Pt 1):43-56.

24. Bushnell MC, Ceko M, Low LA. Cognitive and emotional control of pain and its disruption in chronic pain. Nat Rev Neurosci. 2013 Jul; 14(7):502-11. doi: 10.1038/nrn3516. Epub 2013 May 30.

25. Ossipov MH, Dussor GO, Porreca F. Central modulation of pain. J Clin Invest. 2010 Nov;120(11):3779-87. doi: 10.1172/JCI43766. Epub 2010 Nov 1.

26. Lewis GN, Rice DA, McNair PJ. Conditioned pain modulation in populations with chronic pain: a systematic review and meta-analysis. J Pain. 2012 Oct;13(10):936-44. doi: 10.1016/j.jpain.2012.07.005. Epub 2012 Sep 13.

27. Apkarian AV, Sosa Y, Sonty S, et al. Chronic back pain is associated with decreased prefrontal and thalamic gray matter density. J Neurosci. 2004 Nov 17;24(46):10410-5.

28. Grachev ID, Fredrickson BE, Apkarian AV. Abnormal brain chemistry in chronic back pain: an in vivo proton magnetic resonance spectroscopy study. Pain. 2000 Dec 15;89(1):7-18.

29. Ford GK, Moriarty O, McGuire BE, Finn DP. Investigating the effects of distracting stimuli on nociceptive behaviour and associated alterations in brain monoamines in rats. Eur J Pain. 2008 Nov;12(8):970-9. doi: 10.1016/j.ejpain. 2008.01.002. Epub 2008 Mar 4.

30. Rodriguez-Raecke R, Niemeier A, Ihle K, et al. Brain gray matter decrease in chronic pain is the consequence and not the cause of pain. J Neurosci. 2009 Nov 4;29(44):13746-50. doi: 10.1523/JNEUROSCI.3687-09.2009.

31. Jensen KB, Kosek E, Wicksell R, et al. Cognitive Behavioral Therapy increases pain-evoked activation of the prefrontal cortex in patients with fibromyalgia. Pain. 2012 Jul;153(7):1495-503. doi: 10.1016/j.pain.2012.04.010. Epub 2012 May 20.

32. Zeidan F, Martucci KT, Kraft RA, et al. Brain mechanisms supporting the modulation of pain by mindfulness meditation. J Neurosci. 2011 Apr 6;31(14):5540-8. doi: 10.1523/JNEUROSCI.5791-10.2011.

33. Pessoa L. On the relationship between emotion and cognition. Nat Rev Neurosci. 2008 Feb;9(2):148-58. doi: 10.1038/nrn2317.


For citation:


Koberskaya N.N., Tabeeva G.R. Chronic pain-associated cognitive impairment. Neurology, Neuropsychiatry, Psychosomatics. 2017;9(3):4-9. (In Russ.) https://doi.org/10.14412/2074-2711-2017-3-4-9

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ISSN 2074-2711 (Print)
ISSN 2310-1342 (Online)