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Chronic cerebral ischemia, neuroplasticity, possibilities of therapy

https://doi.org/10.14412/2074-2711-2017-2-102-107

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Abstract

The paper presents current views on the pathogenetic mechanisms of cerebral ischemia. It discusses the role of neurotrophins in the processes of neuroplasticity. Experimental and clinical studies of the neuropeptide drug Cerebrolysin are reviewed. The authors describe in detail the results of the clinical trial and a health economic analysis of the effects of Cerebrolysin on the time course of clinical changes, progression, and risk of exacerbations in patients with chronic cerebral ischemia. 

About the Authors

E. I. Chukanova
N.I. Pirogov Russian National Medical Research University, Ministry of Health of Russia, Moscow
Russian Federation

Department of Neurology, Neurosurgery, and Medical Genetics, Faculty of General Medicine

1, Ostrovityanov St., Moscow 117997



A. S. Chukanova
N.I. Pirogov Russian National Medical Research University, Ministry of Health of Russia, Moscow
Russian Federation

Department of Neurology, Neurosurgery, and Medical Genetics, Faculty of General Medicine

1, Ostrovityanov St., Moscow 117997



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For citation:


Chukanova E.I., Chukanova A.S. Chronic cerebral ischemia, neuroplasticity, possibilities of therapy. Neurology, Neuropsychiatry, Psychosomatics. 2017;9(2):102-107. (In Russ.) https://doi.org/10.14412/2074-2711-2017-2-102-107

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