Current aspects of the epidemiology and treatment of chronic brain ischemiain the presence of essential hypertension (results of the CALIPSO program)
Abstract
The paper gives the results of the multicenter clinical and epidemiological program CALIPSO (Cavinton in the treatment of patients with
chronic cerebral circulatory disorder: dyscirculatory encephalopathy in the presence of essential hypertension). The program covered 4865
patients with chronic hypertension-related cerebrovascular insufficiency from 42 cities and towns of the Russian Federation. The patients
received dropwise intravenous Cavinton as infusions within the first week (25 mg on days 1 to 4 and 50 mg on days 5 to 7) then oral Cavinton
forte, 30 mg/day, for 90 days. Therapy with Cavinton and Cavinton forte led to improvements in health, balance (the Tinnetti scale), and
cognitive functions (the mini mental state examination). This study has provided evidence for the safety of Cavinton.
chronic cerebral circulatory disorder: dyscirculatory encephalopathy in the presence of essential hypertension). The program covered 4865
patients with chronic hypertension-related cerebrovascular insufficiency from 42 cities and towns of the Russian Federation. The patients
received dropwise intravenous Cavinton as infusions within the first week (25 mg on days 1 to 4 and 50 mg on days 5 to 7) then oral Cavinton
forte, 30 mg/day, for 90 days. Therapy with Cavinton and Cavinton forte led to improvements in health, balance (the Tinnetti scale), and
cognitive functions (the mini mental state examination). This study has provided evidence for the safety of Cavinton.
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For citation:
Chukanova E.I., Chukanova E.I. Current aspects of the epidemiology and treatment of chronic brain ischemiain the presence of essential hypertension (results of the CALIPSO program). Neurology, Neuropsychiatry, Psychosomatics. 2011;3(1):38-42. (In Russ.) https://doi.org/10.14412/2074-2711-2011-132
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