AFFECTIVE DISORDERS IN MYASTHENIA
https://doi.org/10.14412/2074-2711-2016-4-21-24
Abstract
Objective: to study of the emotional features in patients with myasthenia.
Patients and methods. 52 myasthenic patients (11 men and 41 women; mean age, 50.5±13.8 years) were examined. The investigators determined the level of situational and personal anxiety (SA and PA) by the Spielberger-Hanin questionnaire and that of depression by the Zung scale. They clarified the association of these indicators with gender, age, myasthenia duration and severity by the Myasthenia Gravis Foundation of America (MGFA) scale, and with the presence of crises.
Results and discussion. The patients with myasthenia showed a higher level of SA than those with depression. There was an increase in the indicators depending on age and disease duration and severity according to the MGFA scale, and on the group of disability. A number of patients who were critically ill and had high MGFA scores were noted to have low PA levels, which may contribute to the decreased level of protective psychological mechanisms.
Conclusion. Most myasthenic patients have high levels of anxiety. In these patients, the absence of depression or the presence of its mild form and the prevalence of anxiety determine the choice of therapy with a preference being given to psychotherapy.
About the Authors
D. Yu. Konkova
Amur State Medical Academy
Russian Federation
Russian Federation
Daria Yuryevna Konkova - Department of Nervous System Disorders, Psychiatry, and Narcology.
95, Gorky St., Blagoveshchensk, Amur Region 675000, fortunka2009@mail.ru
V. N. Karnaukh
Amur State Medical Academy
Russian Federation
Russian Federation
Department of Nervous System Disorders, Psychiatry, and Narcology.
95, Gorky St., Blagoveshchensk, Amur Region 675000
References
1. Антипова ЛН, Миненко ВВ, Шутова ИВ и др. Иммунный статус и психологические особенности больных миастенией. Нейроиммунология. 2004;2(2):7. [Antipova LN, Minenko VV, Shutova IV, et al. Immune status and psychological characteristics of patients with myasthenia gravis. Neiroimmunologiya. 2004;2(2):7. (In Russ.)].
2. Григорьева ВН, Руин ВА. Влияние психического напряжения на клинические проявления в течение генерализованной формы миастении. Журнал неврологии и психиатрии им. С.С. Корсакова. 2007;(6):17-26. [Grigor'eva VN, Ruin VA. The effect of mental stress on clinical manifestations for generalized forms of myasthenia gravis. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. 2007;(6):17-26. (In Russ.)].
3. Петрова НН, Чухловина МЛ, Чухловин АА. Аффективные расстройства и качество жизни у больных миастенией. Обозрение психиатрии и медицинской психологии. 2005(4):34-7. [Petrova NN, Chukhlovina ML, Chukhlovin AA. Affective disorders and quality of life in patients with myasthenia. Obozrenie psikhiatrii i meditsinskoi psikhologii. 2005(4):34-7. (In Russ.)].
4. Doering S, Henze T, Schussler G. Coping with myasthenia gravis and implications for psychotherapy. Arch Neurol. 1993 Jun;50(6):617-20.
5. Mang S, Weiss H, Schalke B. Psychosomatic aspects of myasthenia gravis. A critical review of the literature. Z Klin Psychol Psychopathol Psychother. 1993;41(1):69-86.
6. Tennant C, Wilby J, Nicholson GA. Psychological correlates of myasthenia gravis: a brief report. J Psychosom Res. 1986;30(5): 575-80.
7. Kulaksizoglu IB. Mood and Anxiety Disorders in Patients with Myasthenia Gravis. CNS Drugs. 2007;21(6):473-81.
8. Rü egga SJ, Dirnhoferb S, Buitrago-Tellezc CH. Life-threatening myasthenia gravis masked by a psychiatric disorder. SchweizeracArchiv Furn Neurologie und psychiatrie. 2007;(4):150-4.
9. Knieling J, Wess H, Faller H, et al. Followup of myasthenia gravis. Results of longitudinal study of the significance of psychosocial predictors. Nervenarzt. 1998 Feb;69(2):137-44.
10. Дерманова ИБ. Исследование тревожности. В кн.: Спилбергер ЧД. Диагностика эмоционально-нравственного развития. СПб; 2002. С. 124-6. [Dermanova IB. Study of anxiety. In: Spilberger ChD. Diagnostika emotsional'no-nravstvennogo razvitiya [Diagnostics of emotional and moral development]. SPb; 2002. P. 124-6.]
11. Zung WW, Richards CB, Short MJ. Selfrating depression scale in an outpatient clinic. Further validation of the SDS. Arch Gen Psychiatry. 1965 Dec;13(6):508-15.
12. Parada P, Oliva M, Lаzaro E, et al. Anxiety, Depression and Self-Efficacy in Patients with Myasthenia Gravis. InternatIonal Journal of Psychology & PsychologIcal therapy. 2014;14(1):105-13.
13. Sitek EJ, Bilinska MM, Wieczorek D, Nyka WM. Neuropsychological assessment in myasthenia gravis. Neurol Sci. 2009 Feb;30(1): 9-14. doi: 10.1007/s10072-008-0001-y. Epub 2009 Jan 16.
14. Ybarra MI, Kummer A, Frota ER, et al. Psychiatric Disorders in myasthenia gravis. Arq Neuropsiquiatr. 2011 Apr;69(2A):176-9.
15. Смолин АИ. Миастения: варианты клинического течения, дифференцированное лечение и качество жизни пациентов. Дисс. канд. мед. наук. Иркутск; 2015. [Smolin AI. Myasthenia gravis: the variants of clinical course, differential treatment and quality of life of patients. Diss. cand. med. sci. Irkutsk; 2015.]
16. Антохин ЕЮ. Гендерные аспекты психогенных депрессий: особенности клиники, походы к терапии. Социальная и клиническая психиатрия. 2010;(2):52-61. [Antokhin EYu. Gender aspects of psychogenic depression: features of clinic, approaches to therapy. Sotsial'naya i klinicheskaya psikhiatriya. 2010;(2):52-61. (In Russ.)].
17. Бочкарёва АВ, Холмогорова АБ. Гендерные факторы депрессивных расстройств. Материалы XIV съезда психиатров России. Москва; 2005. 389 с. [Bochkareva AV, Kholmogorova AB. Gender factors of depressive disorders. Materials of XIV Congress of psychiatrists of Russia. Moscow; 2005. 389 p.]
18. Колесников ИА. Невротические депрессивные расстройства и семейное функционирование у беременных женщин (в связи с задачами психотерапии). Автореф. дисс. канд. мед. наук. СПб; 2010. [Kolesnikov IA. Neurotic depressive disorders and family functioning among pregnant women (in connection with tasks of psychotherapy). Autoref. diss. cand. med. sci. SPb; 2010.]
19. Bebbington P, Dunn G, Jenkins R, et al. The influence of age and sex on the prevalence of depressive conditions: report from the National Survey of Psychiatric Morbidity. Int Rev Psychiatry. 2003 Feb-May;15(1-2):74-83.
20. Краснова ОВ, Лидерс АГ. Психология старости и старения. Хрестоматия. Москва: ACADEMA; 2003. 416 с. [Krasnova OV, Liders AG. Psikhologiya starosti i stareniya. Khrestomatiya [The psychology of aging. Reader]. Mocow: ACADEMA; 2003. 416 p.]
21. Кондратьева МВ. Подражание в системе поведенческих паттернов взрослого человека. Материалы IV международной научной конференции студентов, аспирантов, молодых ученых «Научный потенциал студенчества в ХХI веке». Т.2. Общественные науки. Ставрополь: Сев. Кав. ГТУ; 2010. C. 211-4. [Kondrat'eva MV. Imitation in a system of behavioral patterns of an adult. Proceedings of the IV international scientific conference of students, postgraduates and young scientists «the Scientific potential of students in the XXI century». Vol.2. Social Sciences. Stavropol': Sev. Kav. GTU; 2010. P. 211-4.]
22. Чухловина МЛ, Шабалов НП, Цинзерлинг НВ. Особенности патогенеза, клиники и диагностики миастении в детском возрасте. Педиатрия. 2006;(3):90-4. [Chukhlovina ML, Shabalov NP, Tsinzerling NV. Pathogenesis, clinics and diagnosis of myasthenia gravis in children. Pediatriya. 2006;(3):90-4. (In Russ).].
23. Курпатов АВ, Аверьянов ГГ. Руководство по системной поведенческой психотерапии. Москва: ОЛМА Медиа Групп; 2007. 576 с. [Kurpatov AV, Aver'yanov GG. Rukovodstvo po sistemnoi povedencheskoi psikhoterapii [Guide to systemic behavioral psychotherapy]. Moscow: OLMA Media Grupp; 2007. 576 p.]
Review
For citations:
Konkova D.Yu., Karnaukh V.N. AFFECTIVE DISORDERS IN MYASTHENIA. Neurology, Neuropsychiatry, Psychosomatics. 2016;8(4):21-24. (In Russ.) https://doi.org/10.14412/2074-2711-2016-4-21-24
Views: 836
Email this article 