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Experience in using levodopa-benserazide

https://doi.org/10.14412/2074-2711-2015-3-93-97

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Abstract

Levodopa remains the most effective drug for the treatment of Parkinson's disease. The paper considers the mechanism of action, recommended levodopa doses, the time of therapy initiation, and risk factors for motor complications. A few dosage forms of levodopa are currently being used. The results of comparative trials of levodopa-benserazide and levodopa-carbidopa and the clinical experience with Levodopa/Benserazide-Teva are given. An open-label multicenter trial of Levodopa/Benserazide-Teva has shown its high efficacy and good tolerability.

About the Authors

Elena Anatolyevna Katunina
N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia
Russian Federation

Department of Neurology, Neurosurgery, and Medical Genetics, 

1, Ostrovityanov St., Moscow 117997



Yu. N. Bezdolnyi
N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia
Russian Federation

Department of Neurology, Neurosurgery, and Medical Genetics, 

1, Ostrovityanov St., Moscow 117997



E. A. Malykhina
N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia
Russian Federation

Department of Neurology, Neurosurgery, and Medical Genetics, 

1, Ostrovityanov St., Moscow 117997



N. V. Titova
N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia
Russian Federation

Department of Neurology, Neurosurgery, and Medical Genetics, 

1, Ostrovityanov St., Moscow 117997



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For citation:


Katunina E.A., Bezdolnyi Y.N., Malykhina E.A., Titova N.V. Experience in using levodopa-benserazide. Neurology, Neuropsychiatry, Psychosomatics. 2015;7(3):93-97. (In Russ.) https://doi.org/10.14412/2074-2711-2015-3-93-97

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ISSN 2074-2711 (Print)
ISSN 2310-1342 (Online)