Preview

Neurology, Neuropsychiatry, Psychosomatics

Advanced search

Cognitive impairments in clinical practice and analyzing the work of a memory room in Yaroslavl (an outpatient reception)

https://doi.org/10.14412/2074-2711-2014-3-32-37

Full Text:

Abstract

The early diagnosis and treatment of cognitive impairments (CIs) are presently one of the most relevant and sociomedical problems. Since 2012, a memory room that performs an outpatient reception of patients complaining of diminished memory has been working at the Department of Neurology and Medical Genetics with Course of Neurosurgery, Yaroslavl State Medical Academy. The main goals of this subdivision are to make a diagnosis and differential diagnosis of CI, to manage patients with higher brain dysfunctions, to improve quality of life, and to elaborate rehabilitation programs.

Objective: to assess the first results of work of a memory room and to study CIs in patients complaining of diminished memory at the time of their asking for medical advice.

Patients and methods. The two-year data obtained in examining the work of the memory room were analyzed. In January 2012 to January 2014, a total of 250 patients (31% men and 69% women) (mean age 52.4 years (18 to 87 years)) visited the memory room. CIs were rated using the Schulte test, studying short-term visual memory, its volume, and accuracy by mnestic tests and numbers memory tests recording the number of errors; the hospital anxiety and depression Scale and SF-36 questionnaire to estimate quality of life were applied. The efficiency of vinpocetine therapy was investigated in 20 patients (13 women and 7 men) aged 45 to 59 years (mean age 56.3±1.7 years) with moderate CIs of vascular genesis.

Results and discussion. Varying degrees of CIs were identified in 96% of the patients during their first visit to the room. The findings could estimate the approximate incidence and prevalence of CIs in the patients during different pathological processes. There was a preponderance of patients with dementia, the main cause of which was Alzheimer's disease among those who were seeking for medical advice for complaints of amnestic disorders. Vascular processes are a cause of the majority of non-dementia CIs. There are preliminary data on the association between CIs and other neuropsychiatric disorders.

About the Authors

N. V. Pizova
Department of Neurology and Medical Genetics with Course of Neurosurgery, Yaroslavl State Medical Academy, Ministry of Health of Russia
Russian Federation

Yaroslavl, Russia 5, Revolutsionnaya St., Yaroslavl 150000



M. V. Danilova
Department of Neurology and Medical Genetics with Course of Neurosurgery, Yaroslavl State Medical Academy, Ministry of Health of Russia
Russian Federation
Yaroslavl, Russia 5, Revolutsionnaya St., Yaroslavl 150000


References

1. Яхно НН. Когнитивные расстройства в неврологической клинике. Неврологический журнал. 2006;11(S1):4–12. [Yakhno NN. Cognitive impairment in neurological clinical practice. Nevrologicheskii zhurnal. 2006;11(S1):4–12. (In Russ.)]

2. Яхно НН, Захаров ВВ, Локшина АБ и др. Деменции. Руководство для врачей. 2-е изд. Москва: Медпресс-информ; 2010. 272 с. [Yakhno NN, Zakharov VV, Lokshina AB, et al. Dementsii. Rukovodstvo dlya vrachei [Dementias. The management for doctors]. 2nd ed. Moscow: Medpress-inform; 2010. 272 p.]

3. Пизова НВ. Когнитивные расстройства в практике невролога. Consilium Medicum. Приложение Неврология и ревматология. 2013;(2):78–83. [Pizova NV. Cognitive frustration in practice of the neurologist. Consilium Medicum. Suppl Nevrologiya i revmatologiya. 2013;(2):78–83. (In Russ.)]

4. Larrabee GJ, Crook TM. Estimated prevalence of age associated memory impairment derived from standardized tests of memory function. Int Psychogeriatr. 1994;6(1):95–104. DOI: http://dx.doi.org/10.1017/S1041610294001663.

5. Захаров ВВ. Когнитивные нарушения в неврологической практике. Трудный пациент. 2005;3(5):4–9. [Zakharov VV. Cognitive violations in neurologic practice. Trudnyi patsient. 2005;3(5):4–9. (In Russ.)]

6. Golomb J, Kluger A, Garrard P, Ferris S. Clinician’s manual on mild cognitive impairment. London: Science Press Ltd; 2001. 56 з.

7. Jonsson L, Gustavsson A, Cortes F, et al. International differences in resource use and cost of care in Alzgeimer's disease: baseline data from the Ictus Study. Neurodegenerative Dis. 2007;4(1):122.

8. Лурия АР. Основы нейропсихологии. Москва: Издательство МГУ; 1973. 374 с. [Luriya AR. Osnovy neiropsikhologii [Neuropsychology bases]. Moscow: MGU Publishing; 1973. 374 p.]

9. Дамулин ИВ. Болезнь Альцгеймера и сосудистая деменция. Под ред. Н.Н. Яхно. Москва; 2002. 85 с. [Damulin IV. Bolezn' Al'tsgeimera i sosudistaya dementsiya [Alzheimer’s disease and vascular dementia]. Yakhno NN, editor. Moscow; 2002. 85 p.]

10. Ahmadzadeh GH, Farhat A, Soltani D. Prevalence of cognitive dysfunction in old patients admitted in emergency room. Neurodegenerative Dis. 2007;4(1):124.

11. Дамулин ИВ. Сосудистые когнитивные нарушения: клинические и терапевтические аспекты. русский медицинский журнал. 2006;(9):658–64. [Damulin IV. Vascular cognitive disorders: clinical and therapeutic aspects. Russkii meditsinskii zhurnal. 2006;(9):658–64. (In Russ.)]

12. Geroldi C, Ferrucci L, Bandinelli S, et al. Mild cognitive deterioration with subcortical features: prevalence, clinical characteristics, and association with cardiovascular risk factors in community-dwelling older persons (The InCHIANTI Study). J Am Geriart Soc. 2003;51:1064–71. DOI: http://dx.doi.org/10.1046/j.1532-5415.2003.51353.x.

13. Парфенов ВА. Сосудистые когнитивные расстройства. Применение холина альфосцерата. Нервные болезни. 2013;(2):3–9. [Parfenov VA. Vascular cognitive frustration. Application the alfostserata is well-cared. Nervnye bolezni. 2013;(2):3–9. (In Russ.)]

14. Парфенов ВА, Старчина ЮА. Когнитивные нарушения у пацентов с артериальной гипертензией и их лечение. Неврология, нейропсихиатрия, психосоматика. 2011;(1):27–33. [Parfenov VA, Starchina YuA. Cognitive disorders in patients with essential hypertension and their treatment. Nevrologiya, neiropsikhiatriya, psikhosomatika = Neurology, Neuropsychiatry, Psychosomatics. 2011;(1):27–33. (In Russ.)]. DOI: http://dx.doi.org/10.14412/2074-2711-2011-130.

15. Варакин ЮЯ. Профилактика нарушений мозгового кровообращения. Очерки ангионеврологии. Под ред. З.А. Суслина. Москва: Атмосфера; 2005. 368 с. [Varakin YuYa. Profilaktika narushenii mozgovogo krovoobrashcheniya. Ocherki angionevrologii [Prevention of cerebral circulation. Essays angioneurology]. Suslina ZA, editor. Moscow: Atmosfera; 2005. 368 р.]

16. Вe Leeuw FE, van Gijn J. Vascular dementia. Pract Neurol. 2003;3:86–91. DOI: http://dx.doi.org/10.1046/j.1474-7766.2003.04132.x.

17. Bennett SJ, Sauve MJ. Cognitive deficits in patients with heart failure: a review of the literature. J Cardiovasc Nurs. 2003;18(3):219–42. DOI: http://dx.doi.org/10.1097/00005082- 200307000-00007.

18. Vogels RLC, Scheltens P, Schroeder-Tanka JM, Weinstein HC. Cognitive impairment in heart failure: a systematic review of the literature. Eur J Heart Fail. 2007;9(5):440–9. DOI: http://dx.doi.org/10.1016/j.ejheart.2006.11.001.

19. Vogels RLC, Oosterman JM, van Harten B, et al. Profile of cognitive impairment in chronic heart failure. J Am Geriatr Soc. 2007;55(11):1764–70. DOI: http://dx.doi.org/ 10.1111/j.1532-5415.2007.01395.x.

20. Bauer LC, Johnson JK, Pozehl BJ. Cognition in heart failure: an overview of the concepts and their measures. J Am Acad Nurse Pract. 2011;23(11):577–85. DOI: 10.1111/j.1745- 7599.2011.00668.x.

21. Кадыков АС, Шахпаронова НВ. Хронические прогрессирующие сосудистые заболевания головного мозга и деменция. Consilium Medicum. 2002;4(2):71–7. [Kadykov AS, Shakhparonova NV. The chronic progressing vascular diseases of a brain and dementia. Consilium Medicum. 2002;4(2):71–7. (In Russ.)]

22. Климов ЛВ, Парфенов ВА. Когнитивные нарушения в остром периоде ишемического инсульта. Неврологический журнал. 2006;11(S1):53–7. [Klimov LV, Parfenov VA. Cognitive impairment in the acute period of ischemic stroke. Nevrologicheskii zhurnal. 2006;11(S1):53–7. (In Russ.)]

23. Ballard C, Rowan E, Stephens S, et al. Prospective follow-up study between 3 and 15 months after stroke: improvements and decline in cognitive function among dementia-free stroke survivors >75 years of age. Stroke. 2003;34:2440–4. DOI: http://dx.doi.org/10.1161 /01.STR.0000089923.29724.CE.

24. Kase CS, Wolf PA, Kelly-Hayes M, et al. Intellectual decline after stroke: the Framingham Study. Stroke. 1998;29(4):805–12. DOI: http://dx.doi.org/10.1161/01.STR.29.4.805.

25. Pobjasvaara T, Erkinjuntti T, Ylikoski R, et al. Clinical determinations of poststroke dementia. Stroke. 1998;29(1):75–81. DOI: http://dx.doi.org/10.1161/01.STR.29.1.75.

26. Локшина АБ, Захаров ВВ. Легкие и умеренные когнитивные расстройства при дисциркуляторной энцефалопатии. Неврологический журнал. 2006;11(S1):57–64. [Lokshina АВ, Zakharov VV. Subtle and mild cognitive impairment in patients with cerebrovascular insufficiency.

27. Nevrologicheskii zhurnal. 2006;11(S1):57–64. (In Russ.)]

28. Яхно НН, Левин ОС, Дамулин ИВ. Сопоставление клинических и МРТ-данных при дисциркуляторной энцефалопатии. Сообщение 2: Когнитивные нарушения. Неврологический журнал. 2001;6(3):10–9. [Yakhno NN, Levin OS, Damulin IV. Comparison clinical and MRT-data at cerebral vascular insufficiency. Message 2: Cognitive violations. Nevrologicheskii zhurnal. 2001;6(3):10–9. (In Russ.)]

29. Яхно НН, Захаров ВВ, Локшина АБ. Синдром умеренных когнитивных нарушений при дисциркуляторной энцефалопатии. Журнал неврологии и психиатрии им. С.С. Корсакова. 2005;105(2):13–7. [Yakhno NN, Zakharov VV, Lokshina AB. Moderate cognitive impairment syndrome in cerebral vascular insufficiency. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. 2005;105(2):13–7. (In Russ.)]

30. Яхно НН, Захаров ВВ. Легкие когнитивные нарушения в пожилом возрасте. Неврологический журнал. 2004;9(1):4–8. [Yakhno NN, Zakharov VV. Mild cognitive disorders in the elderly. Nevrologicheskii zhurnal. 2004;9(1):4–8. (In Russ.)]

31. Di Carlo A, Baldereschi M, Amaducci L, et al. Cognitive impairment without dementia in older people: prevalence, vascular risk factors, impact on disability. The Italian longitudinal study of aging. J Am Geriatr Soc. 2000;48:775–82.

32. Локшина АБ, Захаров ВВ. Легкие и умеренные когнитивные расстройства при дисциркуляторной энцефалопатии. Неврологический журнал. 2006;(S1):57–64. [Lokshina АВ, Zakharov VV. Subtle and mild cognitive impairment in patients with cerebrovascular insufficiency. Nevrologicheskii zhurnal. 2006;(S1):57–64. (In Russ.)]

33. Petersen RS, Smith GE, Waring SC, et al. Aging, memory and mild cognitive impairment. Int Psychogeriatr. 1997;9 Suppl 1:37–43. DOI: http://dx.doi.org/10.1017/S1041610297004717.

34. Старчина ЮА, Парфенов ВА. Когнитивные расстройства при цереброваскулярных заболеваниях: диагноз и лечение. Русский медицинский журнал. 2008;16(12):1650–2. [Starchina YuA, Parfenov VA. Cognitive frustration at the cerebrovascular diseases: diagnosis and treatment. Russkii meditsinskii zhurnal. 2008;16(12):1650–2. (In Russ.)]

35. Бурцев ЕМ, Савков ВС, Шпрах ВВ, Бурцев МЕ. 10-летний опыт применения Кавинтона при цереброваскулярных нарушениях. Журнал неврологии и психиатрии им. С.С. Корсакова. 1992;92(1):56–60. [Burtsev EM, Savkov VS, Shprakh VV, Burtsev ME. 10 years' experience of application of Kavinton at the cerebrovascular violations. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. 1992;92(1):56–60. (In Russ.)]

36. Гусев ЕИ, редактор. Кавинтон в эксперименте и клинической практике (методические рекомендации). Москва: Гедеон Рихтер –РГМУ; 1998. 56 с. [Gusev EI, editor. Kavinton v eksperimente i klinicheskoi praktike (metodicheskie rekomendatsii) [Kavinton in experiment and clinical practice (methodical recommendations)]. Moscow: Gedeon Rikhter – RGMU; 1998. 56 p.]

37. Khorvat Sh. Kavinton in therapy of chronic insufficiency of brain blood circulation. Orvosi Hetilap. 2001;8:383–9.

38. Карпов АВ. Применение препарата Кавинтон форте у больных с дисциркуляторной энцефалопатией. Русский медицинский журнал. 2004;12(10):626–30. [Karpov AV. Application of a preparation Kavinton forte at patients with cerebral vascular insufficiency. Russkii meditsinskii zhurnal. 2004;12(10):626–30. (In Russ.)]

39. Спирин НН, Пизова НВ, Шадричев ВА и др. Кавинтон у больных с лакунарным инсультом, развившимся на фоне сахарного диабета и артериальной гипертензии. Журнал неврологии и психиатрии им. С.С. Корсакова. 2001;101(Приложение 1):34–40. [Spirin NN, Pizova NV, Shadrichev VA, et al. Kavinton at patients with the lacunary stroke which developed against diabetes and arterial hypertension. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. 2001;101(Suppl 1):34–40. (In Russ.)]

40. Суслина ЗА, Танашян ММ, Ионова ВГ. Кавинтон в лечении больных с ишемическими нарушениями мозгового кровообращения. Русский медицинский журнал. 2002;10(25):1170–4. [Suslina ZA, Tanashyan MM, Ionova VG. Kavinton in treatment of patients with ischemic violations of brain blood circulation. Russkii meditsinskii zhurnal. 2002;10(25):1170–4. (In Russ.)]

41. Coleston DM, Hindmarch I. Possible memoryenhancing properties of vinpocetine. Drug Dev Res. 1988;14:191–3. DOI: http://dx.doi.org/10.1002/ddr.430140306.

42. Fischhof PK, Moslinger-Gehmayr R, Herrmann WM, et al. Therapeutic efficacy of vincamine in dementia. Neuropsychobiol. 1996;34:29–35. DOI: http://dx.doi.org/10.1159/000119288.


For citation:


Pizova N.V., Danilova M.V. Cognitive impairments in clinical practice and analyzing the work of a memory room in Yaroslavl (an outpatient reception). Neurology, Neuropsychiatry, Psychosomatics. 2014;6(3):32-37. (In Russ.) https://doi.org/10.14412/2074-2711-2014-3-32-37

Views: 502


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2074-2711 (Print)
ISSN 2310-1342 (Online)