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Intracranial atherosclerosis: Causes of ischemic stroke, diagnosis, and treatment

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The paper reviews the literature on the identification of the causes of ischemic stroke and transient ischemic attacks in intracranial atherosclerosis. Symptomatic intracranial atherosclerosis is the cause of an ischemic focus in not only the cortical and subcortical structures due to hypoperfusion or arterio-arterial embolism, but also in the deep structures of the cerebral hemispheres and brainstem. Major artery dolichoectasia may make an accurate diagnosis and treatment choice difficult.

Progress in the treatment of patients with symptomatic intracranial atherosclerosis depends on the availability of current brain and vessel imaging techniques and cranial artery angioplasty and stenting methods. The efficiency of aggressive medical prevention, primarily blood pressure reduction and different combinations of antiplatelet drugs, is being intensively investigated.

About the Authors

V.A Sorokoumov
I.P. Pavlov Saint Petersburg State Medical University, Ministry of Health of Russia, Saint Petersburg, 6–8, Lev Tolstoy St., Saint Petersburg 197022
Russian Federation

A.V. Savello
S.M. Kirov Military Medical Academy, Ministry of Defense of the Russian Federation, Saint Petersburg; 6, Academician Lebedev St., Saint Petersburg 194044
Russian Federation


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For citation:

Sorokoumov V., Savello A. Intracranial atherosclerosis: Causes of ischemic stroke, diagnosis, and treatment. Neurology, Neuropsychiatry, Psychosomatics. 2014;6(2S):50-55. (In Russ.)

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