Treatment for poststroke spasticity, the use of mydocalm

Abstract

The paper gives the data available in the literature on the treatment of spasticity in poststroke patients. Therapeutic exercises that should be started just on the first days of stroke are noted to play a leading role in the treatment of poststroke spasticity. The local administration of botulinum toxin preparations (botox, dysport, xeomin) may be effective for managing local spasticity that deteriorates motor functions. Baclofen (baklosan), tizanidine (sirdalud), and tolperisone hydrochloride (mydocalm) may be used as oral medications. The paper also presents the results of a placebo-controlled trial that has indicated that mydocalm given in a dose of 300 to 900 mg/day may be effective in treating poststroke spasticity.