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The integration of new dosage forms into the treatment of vascular cognitive impairment

https://doi.org/10.14412/2074-2711-2026-3-85-92

Abstract

This article reviews current approaches to the diagnosis and treatment of vascular cognitive impairment (VCI). It outlines the key provisions of the updated diagnostic criteria for vascular cognitive impairment from the international VasCog-2-WSO society (2025) and the STRIVE-2 neuroradiological classification of cerebral small vessel disease (2023). A clinical case report is presented of a 63-yearold female patient with mild VCI against a background of arterial hypertension, type 2 diabetes mellitus and obesity, in whom brain MRI revealed multiple lacunar infarcts and leukoaraiosis. The prescription of ethylmethylhydroxypyridine succinate in a new prolonged-release form (Armadin Long) is justified. The drug’s multimodal mechanism of action (antioxidant, antihypoxic, neuroprotective) corresponds to the key pathogenetic mechanisms of VCI, which justifies the choice of this drug for long-term treatment of cognitive disorders.

About the Authors

V. V. Zakharov
Department of Nervous Diseases, N.V. Sklifosovsky Institute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)
Russian Federation

Vladimir Vladimirovich Zakharov 

11, Rossolimo St., Build. 1, Moscow 119021 


Competing Interests:

The conflict of interests did not affect the results of the study. 



O. O. Martynova
Clinical Hospital № 85 of the Federal Medical Biological Agency
Russian Federation

16, Moskvorechye St., Moscow, 115409 


Competing Interests:

The conflict of interests did not affect the results of the study. 



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For citations:


Zakharov VV, Martynova OO. The integration of new dosage forms into the treatment of vascular cognitive impairment. Nevrologiya, neiropsikhiatriya, psikhosomatika = Neurology, Neuropsychiatry, Psychosomatics. 2026;18(3):85-92. (In Russ.) https://doi.org/10.14412/2074-2711-2026-3-85-92

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ISSN 2074-2711 (Print)
ISSN 2310-1342 (Online)