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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">nnp</journal-id><journal-title-group><journal-title xml:lang="en">Neurology, Neuropsychiatry, Psychosomatics</journal-title><trans-title-group xml:lang="ru"><trans-title>Неврология, нейропсихиатрия, психосоматика</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-2711</issn><issn pub-type="epub">2310-1342</issn><publisher><publisher-name>"IMA-Press", LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/2074-2711-2026-3-85-92</article-id><article-id custom-type="elpub" pub-id-type="custom">nnp-2863</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL OBSERVATIONS</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ НАБЛЮДЕНИЯ</subject></subj-group></article-categories><title-group><article-title>The integration of new dosage forms into the treatment of vascular cognitive impairment</article-title><trans-title-group xml:lang="ru"><trans-title>Интеграция новых лекарственных форм в лечение сосудистых когнитивных нарушений</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8447-3264</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Захаров</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zakharov</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Владимир Владимирович Захаров </p><p>119021, Москва, ул. Россолимо, 11, стр. 1 </p></bio><bio xml:lang="en"><p>Vladimir Vladimirovich Zakharov </p><p>11, Rossolimo St., Build. 1, Moscow 119021 </p></bio><email xlink:type="simple">zakharovenator@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3016-540X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мартынова</surname><given-names>О. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Martynova</surname><given-names>O. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115409, ул. Москворечье, 16 </p></bio><bio xml:lang="en"><p>16, Moskvorechye St., Moscow, 115409 </p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Кафедра нервных болезней Института клинической медицины им. Н.В. Склифосовского ФГАОУ ВО «Первый Московский медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский Университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Department of Nervous Diseases, N.V. Sklifosovsky Institute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБУЗ «Клиническая больница №85 ФМБА России»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Clinical Hospital № 85 of the Federal Medical Biological Agency</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>20</day><month>06</month><year>2026</year></pub-date><volume>18</volume><issue>3</issue><fpage>85</fpage><lpage>92</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Zakharov V.V., Martynova O.O., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Захаров В.В., Мартынова О.О.</copyright-holder><copyright-holder xml:lang="en">Zakharov V.V., Martynova O.O.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://nnp.ima-press.net/nnp/article/view/2863">https://nnp.ima-press.net/nnp/article/view/2863</self-uri><abstract><p>This article reviews current approaches to the diagnosis and treatment of vascular cognitive impairment (VCI). It outlines the key provisions of the updated diagnostic criteria for vascular cognitive impairment from the international VasCog-2-WSO society (2025) and the STRIVE-2 neuroradiological classification of cerebral small vessel disease (2023). A clinical case report is presented of a 63-yearold female patient with mild VCI against a background of arterial hypertension, type 2 diabetes mellitus and obesity, in whom brain MRI revealed multiple lacunar infarcts and leukoaraiosis. The prescription of ethylmethylhydroxypyridine succinate in a new prolonged-release form (Armadin Long) is justified. The drug’s multimodal mechanism of action (antioxidant, antihypoxic, neuroprotective) corresponds to the key pathogenetic mechanisms of VCI, which justifies the choice of this drug for long-term treatment of cognitive disorders.</p></abstract><trans-abstract xml:lang="ru"><p>Рассмотрены современные подходы к диагностике и лечению сосудистых когнитивных нарушений (СКН). Приведены основные положения обновленных диагностических критериев СКН международного общества VasCog-2-WSO (2025) и нейрорадиологическая классификация церебральной микроангиопатии STRIVE-2 (2023). Представлено клиническое наблюдение пациентки 63 лет с умеренными СКН на фоне артериальной гипертензии, сахарного диабета 2-го типа и ожирения, у которой по данным МРТ головного мозга выявлены множественные лакунарные инфаркты и лейкоареоз. Обосновано назначение этилметилгидроксипиридина сукцината в новой пролонгированной лекарственной форме (Армадин лонг). Мультимодальный механизм действия препарата (антиоксидантный, антигипоксический, нейропротективный) соответствует ключевым патогенетическим механизмам СКН, что делает обоснованным выбор данного препарата для длительной терапии когнитивных расстройств.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>хроническая ишемия мозга</kwd><kwd>дисциркуляторная энцефалопатия</kwd><kwd>сосудистые когнитивные нарушения</kwd><kwd>нейропротективная терапия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>chronic cerebrovascular disorder</kwd><kwd>cerebrovascular insufficiency</kwd><kwd>vascular cognitive impairment</kwd><kwd>neuroprotective therapy</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Статья спонсируется компанией «Гедеон Рихтер».</funding-statement><funding-statement xml:lang="en">The article is sponsored by Gedeon Richter.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Rizzi L, Rosset I, Roriz-Cruz M. 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