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Dementia: epidemiology, clinical picture, diagnosis, approaches to therapy

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The review of literature discusses in detail the clinical signs of non-dementia cognitive impairments (CIs) and differences between subclinical, mild, and moderate CIs. It considers in detail the manifestations of dementia, the typical clinical picture of the most common forms of dementia, such as Alzheimer’s disease, Lewy body dementia, and vascular dementia. The paper outlines basic approaches to the pathogenetic therapy for dementia and the efficiency and safety of using NMDA receptor antagonists in patients with this pathology.

About the Author

Irina Sergeyevna Preobrazhenskaya
Department of Nervous System Diseases, Faculty of Therapeutics, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia, Moscow
Russian Federation


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For citations:

Preobrazhenskaya I.S. Dementia: epidemiology, clinical picture, diagnosis, approaches to therapy. Neurology, Neuropsychiatry, Psychosomatics. 2013;5(4):71-77. (In Russ.)

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ISSN 2074-2711 (Print)
ISSN 2310-1342 (Online)