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The effect of antiepileptic drugs on cognitive functions

https://doi.org/10.14412/2074-2711-2013-2489

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Abstract

Impaired cognitive function is a common problem in epileptic patients. The exact cause of cognitive impairment in case of epilepsy has not been explored fully, but there is no doubt that a role in this is played by three factors: the disease underlying epilepsy; epileptic seizures proper; and negative side effects of antiepileptic drugs. Their cognitive effects are one of the major problems affecting the tolerance of therapy. The review considers the effects of phenobarbital, phenytoin, carbamazepine, valproates, oxcarbazepine, topiramate, lamotrigine, and levetiracetam in terms of their action on the cognitive function of healthy volunteers and epileptic patients.

About the Author

A. S. Kotov
M.F. Vladimirsky Moscow Regional Research Clinical Institute, Moscow
Russian Federation


References

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For citation:


Kotov A.S. The effect of antiepileptic drugs on cognitive functions. Neurology, Neuropsychiatry, Psychosomatics. 2013;5(1S):45-51. (In Russ.) https://doi.org/10.14412/2074-2711-2013-2489

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