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Osmotic demyelination syndrome: central pontine and extrapontine myelinolysis in a patient in the early postpartum period. Clinical observation

https://doi.org/10.14412/2074-2711-2023-5-39-45

Abstract

The article presents a review of the literature and a description of a clinical case of osmotic demyelination syndrome manifested by pontine and extrapontine myelinolysis in a 36-year-old woman after her third surgical preterm delivery. The reasons for the development of a demyelinating lesion of the central nervous system are discussed, and clinical cases described in world literature sources are presented. An analysis of the pathogenesis of the development of this disease in women during pregnancy, childbirth, and lactation is provided. The importance of this period in a woman's life as an independent significant risk factor for the development of osmotic demyelination syndrome is discussed.

About the Authors

E. V. Isakova
M.F. Vladimirsky Moscow Regional Research Clinical Institute
Russian Federation

61/2, Shchepkina St., Build. 1, Moscow 129110


Competing Interests:

There are no conflicts of interest



E. A. Stepanova
M.F. Vladimirsky Moscow Regional Research Clinical Institute
Russian Federation

61/2, Shchepkina St., Build. 1, Moscow 129110


Competing Interests:

There are no conflicts of interest



S. V. Kotov
M.F. Vladimirsky Moscow Regional Research Clinical Institute
Russian Federation

Sergey Viktorovich Kotov

61/2, Shchepkina St., Build. 1, Moscow 129110


Competing Interests:

There are no conflicts of interest



Yu. A. Belova
M.F. Vladimirsky Moscow Regional Research Clinical Institute
Russian Federation

61/2, Shchepkina St., Build. 1, Moscow 129110


Competing Interests:

There are no conflicts of interest



References

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For citations:


Isakova EV, Stepanova EA, Kotov SV, Belova YA. Osmotic demyelination syndrome: central pontine and extrapontine myelinolysis in a patient in the early postpartum period. Clinical observation. Nevrologiya, neiropsikhiatriya, psikhosomatika = Neurology, Neuropsychiatry, Psychosomatics. 2023;15(5):39-45. https://doi.org/10.14412/2074-2711-2023-5-39-45

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ISSN 2074-2711 (Print)
ISSN 2310-1342 (Online)