Ways to improve adherence to long-term injection therapy in multiple sclerosis using the example of pegylated interferon-β1a (sampeginterferon β-1a)
Abstract
Patient adherence to therapy with multiple sclerosis disease-modifying treatments (MS DMTs) in many cases determine the effectiveness of therapy. The review discusses the reasons for low adherence to DMTs, ways to increase it. Among the most effective ways is to reduce the frequency of administration of the drug while maintaining its high efficiency. To illustrate this, the increase in adherence to treatment with interferon-β drugs due to pegylation is discussed. Without losing its effectiveness, sampeginterferon beta-1a (samPEG-IFN-β1a) administration reduces the frequency of local adverse reactions, partly due to reducing the frequency of injections, which contributes to higher adherence to the treatment.
About the Author
A. N. Boyko
Department of Neurology, Neurosurgery and Medical Genetics, N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia; Institute of Clinical Neurology, Federal Center for Brain and Neurotechnologies, Federal Medical and Biological Agency of Russia
Russian Federation
Russian Federation
Alexey Nikolaevich Boyko
1, Ostrovityanova St., Moscow 117997
1, Ostrovityanova St., Build. 10, Moscow 117997
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Review
Supporting agencies: This article has been supported by Biocad.
For citations:
Boyko A.N. Ways to improve adherence to long-term injection therapy in multiple sclerosis using the example of pegylated interferon-β1a (sampeginterferon β-1a). Neurology, Neuropsychiatry, Psychosomatics. 2022;14(1S):34-37. (In Russ.) https://doi.org/10.14412/2074-2711-2022-1S-34-37
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