Role of chondroitin sulfate in the regulation of neuroimmunoendocrine network interactions in patients with neurological symptoms in the post-covid period
https://doi.org/10.14412/2074-2711-2021-6-105-110
Abstract
The review discusses the prospects for the use of chondroitin sulfate and its derivatives for new indications in patients with and myalgic encephalomyelitis/chronic fatigue syndrome after SARS-CoV-2 infection. The epidemiology, clinical manifestations, main mechanisms of the development of the dysregulation of neuroimmunoendocrine network interactions in long-term COVID-19 are considered. Modern data on the relationship between mechanisms of neuroprotective effects of chondroitin sulfate and its derivatives and their chemical structure characteristics have been analyzed. The position is argued according to which chondroitin sulfate and its derivatives can become promising drugs in prevention of the development of neuroimmunoendocrine network interactions disorders in COVID-19.
About the Authors
I. V. SarvilinaRussian Federation
74, Sotsialisticheskaya St., Rostov-on-Don 344002, Russia
O. A. Gromova
Russian Federation
42, Vavilova St., Build. 2, Moscow 119333, Russia
27, Lomonosovsky Prosp., Build. 1, Moscow 119192, Russia
M. Yu. Maksimova
Russian Federation
80, Volokolamskoe Shosse, Moscow 125367, Russia
M. N. Sharov
Russian Federation
20, Delegatskaya St., Build. 1, Moscow 127473, Russia
21, Vuchetich St., Moscow 127206, Russia
Yu. S. Prokofyeva
Russian Federation
20, Delegatskaya St., Build. 1, Moscow 127473, Russia
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