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Consensus of expert advices on routing, diagnosis, and management of patients with neuromyelitis optica spectrum disorders

https://doi.org/10.14412/2074-2711-2021-5-140-147

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Abstract

Neuromyelitis optica spectrum disorders (NMOSDs) are autoimmune inflammatory disorders accompanied by central nervous system damage, widespread immunemediated demyelination, and axonal damage, involving mainly the optic nerves, spinal cord, and area postrema. The diagnostic capabilities, administration and routing of patients, and therapeutic approaches to this disease need to be improved. During several expert councils held in 2019–2021 in different regions of the Russian Federation, we discussed multiple issues related to various aspects of medical care for patients with NMOSDs. As a result, the experts developed further steps necessary to improve the medical care to these patients: to write and publish clinical guidelines for the diagnosis and treatment of NMOSDs; to consider the possibility of optimizing the NMOSDs diagnostic program including the aquaporin-4 antibodies (AQP4-IgG) testing; to evaluate the implementation of a set of measures aimed at including the corresponding laboratory investigations into the system of state guarantees (together with the institutions of the Ministry of Health of Russia), if there is clinical and economic feasibility; to include the issues of timely NMOSDs evaluation in educational programs initiated by the scientific medical community, in order to raise awareness of primary care neurologists in relation to the clinical and neuroimaging signs of probable NMOSDs; to assess the possibility of introducing routing schemes for patients with NMOSDs at the regional level; to work out a decision on the collection of NMOSDs epidemiological and clinical data in the Russian Federation.

About the Authors

A. N. Boyko
N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia; Federal Center of Brain and Neurotechnologies, FMBA of Russia
Russian Federation

Aleksey Nikolaevich Boyko

Department of Neurology, Neurosurgery, and Medical Genetics

Institute of clinical neurology

1, Ostrovityanov St., Moscow 117997
1, Ostrovityanov St., Build 10, Moscow 117997



K. Z. Bakhtiyarova
Bashkir State Medical University, Ministry of Health of Russia
Russian Federation

47, Zaki Validi St., Ufa 450008



L. V. Brylev
V.M. Buyanov City Clinical Hospital
Russian Federation

First Neurological Departments

26, Bakinskaya St., Moscow 115516



M. N. Zakharova
M.V. Lomonosov Moscow State University; Research Center of Neurology
Russian Federation

Department of Fundamental Medicine

Sixth Neurological Department

27, Lomonosovsky Prosp., Build. 1, Moscow 119192
80, Volokolamskoe Shosse, Moscow 125367



D. S. Kasatkin
Yaroslavl State Medical University, Ministry of Health of Russia
Russian Federation

Department of Nervous Diseases with Medical Genetics and Neurosurgery

5, Revolutsionnaya St., Yaroslavl 150000



D. S. Korobko
Novosibirsk State Regional Clinical Hospital
Russian Federation

Center for Multiple Sclerosis and Other Autoimmune Diseases of the Nervous System

130, Nemirovich-Danchenko St., Novosibirsk 630087



S. V. Kotov
M.F. Vladimirsky Moscow Regional Research Clinical Institute
Russian Federation

Department of Neurology, Faculty of Advanced Medical Training

61/2, Shchepkina St., Build. 1, Moscow 129110



V. S. Krasnov
Acad. I.P. Pavlov First Saint Petersburg State Medical University, Ministry of Health of Russia
Russian Federation

Department of Neurology

6–8, Lev Tolstoy St., Saint Petersburg 197022



N. A. Malkova
Novosibirsk State Regional Clinical Hospital; Novosibirsk State Medical University, Ministry of Health of Russia
Russian Federation

Center for Multiple Sclerosis and Other Autoimmune Diseases of the Nervous System

Department of Clinical Neurologyand Neurogeriatrics

130, Nemirovich-Danchenko St., Novosibirsk 630087
1, Pirogov St., Novosibirsk 630090



E. V. Popova
N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia; City Clinical Hospital №24, Moscow Healthcare Department
Russian Federation

Department of Neurology, Neurosurgery, and Medical Genetics

Interdistrict Department of Multiple Sclerosis

1, Ostrovityanov St., Moscow 117997
10, Pistcovaya St., Moscow 127015



S. A. Sivertseva
Kirov State Medical University; Medical and Sanitary Unit «Neftyanik»
Russian Federation

Department of Neurology, Neurosurgery, and Neurorehabilitation

112, K. Marksa St., Kirov 610998
8/1, Yuria Semovskih St., Tyumen 625000



T. O. Simaniv
M.V. Lomonosov Moscow State University
Russian Federation

Department of Fundamental Medicine

27, Lomonosovsky Prosp., Build. 1, Moscow 119192



A. A. Sokolova
Khanty-Mansi State Medical Academy
Russian Federation

Department of Neurology and Psychiatry

40, Mir St., Khanty-Mansiysk 628011



N. A. Totolyan
Acad. I.P. Pavlov First Saint Petersburg State Medical University, Ministry of Health of Russia
Russian Federation

Department of Neurology

6–8, Lev Tolstoy St., Saint Petersburg 197022



T. N. Trushnikova
Perm State Medical University, Ministry of Health of Russia; The «Badge of Honor» Order Perm Regional Clinical Hospital
Russian Federation

Department of Neurology

Center for Multiple Sclerosis of the Perm Territory

26, Petropavlovskaya St., Perm 614990
85, Pushkin St., Perm 614990



F. A. Khabirov
Kazan State Medical Academy, Branch, Russian Medical Academy of Continuing Professional Education, Ministry of Health of Russia; Republican Clinical and Diagnostic Center for Demyelinating Diseases, Ministry of Health of the Republic of Tatarstan
Russian Federation

Department of Neurology

36, Butlerov St., Kazan 420012
13, Vatutin St., Kazan 420021



N. V. Khachanova
N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia; City Clinical Hospital №24, Moscow Healthcare Department
Russian Federation

Department of Neurology, Neurosurgery, and Medical Genetics

Interdistrict Department of Multiple Sclerosis

1, Ostrovityanov St., Moscow 117997
10, Pistcovaya St., Moscow 127015



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For citation:


Boyko A.N., Bakhtiyarova K.Z., Brylev L.V., Zakharova M.N., Kasatkin D.S., Korobko D.S., Kotov S.V., Krasnov V.S., Malkova N.A., Popova E.V., Sivertseva S.A., Simaniv T.O., Sokolova A.A., Totolyan N.A., Trushnikova T.N., Khabirov F.A., Khachanova N.V. Consensus of expert advices on routing, diagnosis, and management of patients with neuromyelitis optica spectrum disorders. Neurology, Neuropsychiatry, Psychosomatics. 2021;13(5):140-147. https://doi.org/10.14412/2074-2711-2021-5-140-147

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ISSN 2074-2711 (Print)
ISSN 2310-1342 (Online)