Treatment of cognitive impairment in arterial hypertension
https://doi.org/10.14412/2074-2711-2021-5-90-95
Abstract
Cognitive impairment (CI) is one of the earliest and most frequent neurological disorders in patients with arterial hypertension. Arterial hypertension is a leading modifiable risk factor for stroke and cerebral microangiopathy, which underlies the development of non-stroke associated CI. Antihypertensive therapy plays an essential role in preventing the development and slowing the progression of CI by controlling blood pressure. The review discusses the use of memantine – a reversible inhibitor of NMDA receptors (akatinol memantine) – in vascular CI.
Keywords
arterial hypertension,
cognitive impairment,
dementia,
antihypertensive therapy,
stroke,
microangiopathy,
memantine
Supporting agencies: This article has been supported by «Merz».
About the Authors
Yu. A. Starchina
I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia
Russian Federation
Russian Federation
Yulia Aleksandrovna Starchina
Department of Nervous System Diseases and Neurosurgery, N.V. Sklifosovsky Institute of Clinical Medicine
11, Rossolimo St., Build. 1, Moscow 119021
K. S. Sleptcova
I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia
Russian Federation
Russian Federation
Department of Nervous System Diseases and Neurosurgery, N.V. Sklifosovsky Institute of Clinical Medicine
11, Rossolimo St., Build. 1, Moscow 119021
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Starchina Yu.A., Sleptcova K.S. Treatment of cognitive impairment in arterial hypertension. Neurology, Neuropsychiatry, Psychosomatics. 2021;13(5):90-95. (In Russ.) https://doi.org/10.14412/2074-2711-2021-5-90-95
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