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Biological basis of aggressive behavior

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The review analyzes the role of serotonergic, dopaminergic, noradrenergic, and glutamatergic systems and neuroendocrine mechanisms, neuropeptides, and inflammatory mediators in aggression manifestation. We discuss the inconsistency of modern concepts about the neurochemical nature of aggressive behavior and the urgency of determining biological markers of social danger. Finally, questions of psychopharmacotherapy of aggressive behavior are reviewed.

About the Authors

O. A. Makushkina
V.P. Serbsky National Medical Research Center of Psychiatry and Narcology, Ministry of Health of Russia
Russian Federation

Oksana Anatolevna Makushkina

23, Kropotkinskiy per., Moscow 119034

O. I. Gurina
V.P. Serbsky National Medical Research Center of Psychiatry and Narcology, Ministry of Health of Russia
Russian Federation

23, Kropotkinskiy per., Moscow 119034

V. A. Golenkova
V.P. Serbsky National Medical Research Center of Psychiatry and Narcology, Ministry of Health of Russia
Russian Federation

23, Kropotkinskiy per., Moscow 119034


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For citation:

Makushkina O.A., Gurina O.I., Golenkova V.A. Biological basis of aggressive behavior. Neurology, Neuropsychiatry, Psychosomatics. 2021;13(5):76-82. (In Russ.)

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