Acute inflammatory demyelinating pseudotumor after COVID-19
https://doi.org/10.14412/2074-2711-2021-1S-57-61
Abstract
The presence of a single demyelinating focus with signs of the blood-brain barrier (BBB) disruption, revealed during magnetic resonance imaging (MRI), in the absence of clinical symptoms, is most often an accidental finding and requires careful follow-up and anamnesis clarification for diagnosis. Such a focus can be a sign of multiple sclerosis onset, be a symptom of acute disseminated encephalomyelitis, inflammatory demyelinating pseudotumor, brain tumor, encephalitis, etc. Difficulties of differential diagnosis in a radiologically isolated syndrome are reflected in the presented clinical case of a 26-year-old woman who had recovered from COVID-19, in whom an MRI revealed a large single focus in the left frontal lobe with signs of active process.
About the Authors
T. I. Yakushina
M.F. Vladimirsky Moscow Regional Research Clinical Institute
Russian Federation
Russian Federation
Tatiana Igorevna Yakushina
61/2, Shchepkin St., Build. 1, Moscow 129110
D. M. Yakushin
M.F. Vladimirsky Moscow Regional Research Clinical Institute
Russian Federation
Russian Federation
61/2, Shchepkin St., Build. 1, Moscow 129110
I. O. Shtang
M.F. Vladimirsky Moscow Regional Research Clinical Institute
Russian Federation
Russian Federation
61/2, Shchepkin St., Build. 1, Moscow 129110
References
1. Boyko AN, Bykov OV, Sivertseva SA. Rasseyannyy skleroz u detey i podrostkov. Klinika, diagnostika i lecheniye [Multiple sclerosis in children and adolescents. Clinic, diagnosis and treatment]. Moscow: MIA; 2016. P. 113-20 (In Russ.).
2. Shmidt TE, Yakhno NN. Rasseyannyi skleroz [Multiple sclerosis]. Moscow: MEDpressinform; 2010. 267 p. (In Russ.).
3. Guseva EI, Zavalishin IA, Boiko AN, editors. Rasseyannyi skleroz. Klinicheskoe rukovodstvo [Multiple sclerosis. Clinical guidelines]. Moscow: Real Taim; 2011. P. 219-77 (In Russ.).
4. Zavalishin IA, Piradov MA, Boyko AN, et al., editors. Autoimmunnyye zabolevaniya v nevrologii. Klinicheskoye rukovodstvo [Autoimmune diseases in neurology. Clinical guidelines]. Moscow; 2014. Vol. 1. P. 16-29 (In Russ.).
5. Kepes JJ. Large focal tumor like demyelination lesion of the brain: intermediate entity between multiple sclerosis and disseminated encephalomyelitis? A study of 31 patients. Ann Neurol. 1993 Jan;33(1):18-27. doi: 10.1002/ana.410330105
6. Bembeyeva RTs, Serkov SV, Pronin IN, Korshunov AG. A case of an acute inflammatory demyelinating process with a pseudotumorous course. Zhurnal nevrologii i psikhiatrii. 2007;(2/1):63-7 (In Russ.).
7. Scott W. Magnetic Resonance Imaging of the Brain and Spine: Atlas. 3 rd ed. Philadelphia: Lippincott Williams & Wilkins; 2002.
8. Panova IN, Stepanova IN. Multiple sclerosis. Combined hospital, LSO, Moscow. Lechashchiy vrach = Attending Physician. 1999;(4):3-5 (In Russ.).
9. Paley RJ, Persing JA, Doctor A, et al. Multiple sclerosis and brain tumor: a diagnostic challenge. J Emerg Med. May-Jun 1989;7(3):241-4. doi: 10.1016/0736-4679(89)90353-3
10. Skripchenko NV, Ivanova GP, Alekseyeva LA, Govorova LV. Criteria for the diagnosis of an unfavorable prognosis in leukoencephalitis in children: a new medical technology. In: Sovremennyye podkhody k diagnostike, terapii i profilaktike infektsionnykh zabolevaniy u detey: Sbornik nauchnykh trudov [Modern approaches to the diagnosis, therapy and prevention of infectious diseases in children: Collection of scientific papers]. St. Petersburg; 2011. Vol. 1. P. 5-29 (In Russ.).
11. Bryukhov VV, Kulikova SN, Krotenkova IA, et al. MRI in the diagnosis of multiple sclerosis. Meditsinskaya vizualizatsiya. 2014;(2):10-21 (In Russ.).
12. Belova YuA, Yakushina TI, Rudakova IG. Pseudotumorous form of multiple sclerosis with symptomatic seizures (clinical observation). Russkiy zhurnal detskoy nevrologii. 2015;10(4):55-60 (In Russ.).
Review
For citations:
Yakushina TI, Yakushin DM, Shtang IO. Acute inflammatory demyelinating pseudotumor after COVID-19. Nevrologiya, neiropsikhiatriya, psikhosomatika = Neurology, Neuropsychiatry, Psychosomatics. 2021;13(1S):57-61. (In Russ.) https://doi.org/10.14412/2074-2711-2021-1S-57-61
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