Preview

Neurology, Neuropsychiatry, Psychosomatics

Advanced search

Chronic cerebral ischemia and headache in patients in primary care physician's practice

https://doi.org/10.14412/2074-2711-2021-1-131-137

Full Text:

Abstract

Today, chronic cerebral ischemia (CCI) is the most common diagnosis in our country, both in neurological and general medical practice. The high frequency of comorbid conditions and diseases predisposing to the development of CCI, and the association with the risk of stroke and dementia, which increase patient disability, make CCI an urgent medical and social problem. Proper diagnosis of CCI allows the prescription of effective treatment, prevents the disease progression, and the development of strokes and dementia. The article deals with the treatment principles for elderly and senile patients with headache and CCI in outpatient practice. It discusses the causes of headache in CCI patients and its treatment methods. It also covers in depth the spectrum of therapeutic effects of Neurox® (ethylmethylhydroxypyridine succinate) and Neupilept® (citicoline) in this category of patients.

About the Authors

V. N. Shishkova
National Medical Research Center for Therapy and Preventive Medicine, Federal State Budgetary Institution, the Ministry of Health of Russia; A.I. Yevdokimov Moscow State University of Medicine and Dentistry, Federal State Budgetary Educational Institution of Higher Education
Russian Federation

Veronika Nikolaevna Shishkova

10-3 Petroverigsky Lane, Moscow, 101990
20-1 Delegatskaya Str., Moscow, 127473 



T. V. Adasheva
National Medical Research Center for Therapy and Preventive Medicine, Federal State Budgetary Institution, the Ministry of Health of Russia; A.I. Yevdokimov Moscow State University of Medicine and Dentistry, Federal State Budgetary Educational Institution of Higher Education
Russian Federation
10-3 Petroverigsky Lane, Moscow, 101990
20-1 Delegatskaya Str., Moscow, 127473


References

1. Grinin VM, Shestemirova EI. Demographic aging in Russia at the present stage. Vestnik RAMN. 2015;70(3):348-54 (In Russ.).

2. Oganov RG, Simanenkov VI, Bakulin IG, et al. Comorbid pathology in clinical practice. Algorithms for diagnosis and treatment. Clinical guidelines. Kardiovaskulyarnaya terapiya i profilaktika. 2019;18(1):5-66 (In Russ.).

3. Putilina MV. Comorbidity in elderly patients.. Zhurnal nevrologii i psikhiatrii. 2016;(5):106-11 (In Russ.).

4. Klinicheskiye rekomendatsii. Starcheskaya asteniya. MKB-10: R-54. Vozrastnaya gruppa: 60 let i starshe [Clinical guidelines. Senile asthenia. ICD-10: R-54. Age group: 60 and over]. Moscow; 2018. 106 p. (In Russ.).

5. Zakharov VV, Yakhno NN. Kognitivnyye rasstroystva v pozhilom i starcheskom vozraste: Metodicheskoye posobiye dlya vrachey [Cognitive Disorders in Old and Old Age: A Methodological Guide for Physicians]. Moscow; 2005. 71 p. (In Russ.).

6. Shishkova VN. The importance of arterial hypertension in the development of brain damage – from mild cognitive impairment to dementia. Sistemnyye gipertenzii. 2014;11(1):45-51 (In Russ.).

7. Boytsov SA, Shal'nova SA, Deyev AD. The epidemiological situation as a factor determining the strategy for reducing mortality in the Russian Federation. Terapevticheskiy arkhiv. 2020;(1):4-9 (In Russ.).

8. Suslina ZA, Varakin YuYa. Klinicheskoye rukovodstvo po ranney diagnostike, lecheniyu i profilaktike sosudistykh zabolevaniy golovnogo mozga [Clinical guidelines for the early diagnosis, treatment and prevention of cerebrovascular diseases]. Moscow: MEDpress-inform; 2017. 352 p. (In Russ.).

9. Skvortsova VI, Shetova IM, Kakorina EP, et al. Results of the implementation of the «Set of measures to improve medical care for patients with acute cerebrovascular accidents in the Russian Federation». Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. 2018;118(4):5-12 (In Russ.).

10. Parfenov VA. Distsirkulyatornaya entsefalopatiya i sosudistyye kognitivnyye rasstroystva [Dyscirculatory encephalopathy and vascular cognitive disorders]. Moscow: IMA-PRESS; 2017. 128 p. (In Russ.).

11. Martynov AI, Vertkin AL, Danilov AB. Consensus on the management of patients with chronic cerebral ischemia for physicians and general practitioners. Terapiya. 2020;41(7):15-21 (In Russ.).

12. Diamanti S, Longoni M, Agostoni EC. Leading symptoms in cerebrovascular diseases: what about headache? Neurol Sci. 2019 May;40(Suppl 1):147-52. doi: 10.1007/s10072019-03793-8

13. Osipova VV. Pervichnyye golovnyye boli v praktike nevrologa i terapevta [Primary headaches in the practice of a neurologist and therapist]. Moscow: GEOTAR-Media; 2018. 104 p. (In Russ.).

14. Headache Classification Committee of the International Headache Society (IHS).The International Classification of Headache Disorders. 3 rd edition. Cephalalgia. 2018;38(1):1-211.

15. Sergeyev AV, Osipova VV, Tabeyeva GR, et al. Syndrome of reversible cerebral vasoconstriction. Nevrologicheskiy zhurnal. 2012;(3):4-11 (In Russ.).

16. Tkacheva ON, Runikhina NK, Vorob'yeva NM, et al. Antithrombotic therapy in old and senile age: the agreed opinion of experts. Kardiovaskulyarnaya terapiya i profilaktika. 2017;16(3):4-33 (In Russ.).

17. Tkacheva ON, Runikhina NK, Kotovskaya YuV, et al. Treatment of arterial hypertension in patients 80 years of age and older and patients with senile asthenia. Clinical guidelines. Zhurnal dlya nepreryvnogo meditsinskogo obrazovaniya vrachey. 2017;(2):76-90 (In Russ.).

18. Orlova YaA, Tkacheva ON, Arutyunov GP, et al. Features of diagnosis and treatment of chronic insufficiency in elderly and senile patients. Kardiologiya. 2018;58(S12):57-85 (In Russ.).

19. Tkacheva ON, Ostroumova OD, Kotovskaya YuV, et al. Deprecribing of sugarlowering drugs in elderly and senile patients: current state of the art and review of the evidence base. Klinicheskaya farmakologiya i terapiya. 2019;28(3):62-7 (In Russ.).

20. Putilina MV, Teplova NV. Ratsional'naya farmakoterapiya khronicheskoy ishemii golovnogo mozga. Klinicheskiye rekomendatsii [Rational pharmacotherapy of chronic cerebral ischemia. Clinical guidelines]. Moscow: MEDpressinform; 2019. 472 p. (In Russ.).

21. Fioravanti M, Yanagi M. Cytidinediphosphocholine (CDP-choline) for cognitive and behavioural disturbances associated with chronic cerebral disorders in the elderly. Cochrane Database Syst Rev. 2005 Apr 18;(2):CD000269. doi: 10.1002/14651858.CD000269.pub3

22. Singh M, Khan MI, Giri R, Kumar L. Rol of citicoline in improvement of cognition, memory and post stroke disability in stroke patients. Int J Advances Med. 2019;6(2):429. doi: 10.18203/2349-3933.ijam20191154

23. Bogolepova AN. The role of oxidative stress in the development of vascular cognitive disorders. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. 2020;120(8):133-9 (In Russ.).

24. Badalyan OL, Savenkov AA, Taisheva KKh, et al. Possibilities of using Neurox in the complex treatment of chronic cerebral ischemia. Russkiy meditsinskiy zhurnal. 2010;18(8):455-9 (In Russ.).

25. Solov'yeva EYu, Amelina IP. Cerebral microangiopathy in the development of chronic cerebral ischemia: approaches to treatment. Meditsinskiy Sovet. 2020;(2):16-24 (In Russ.).

26. Solov'yeva EYu, Karneyev AN, Chekanov AV, et al. Individual and combined antioxidant effects of citicoline and ethylmethylhydroxypyridine succinate. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. 2016;116(11):78-85 (In Russ.).

27. Solovyeva EYu, Karneev AN, Chekanov AV, et al. The study of membrane-protectiveand and antioxidant potentials of citicoline and ethylmethylhydroxypyridine with combined usage. Tikhookeanskiy meditsinskiy zhurnal = Pacific Medical Journal. 2019;(1):74-80. doi: 10.17238/PmJ1609-1175.2019.1.74-80 (In Russ.).

28. Solov'yeva EYu, Karneyev AN, Chekanov AV, et al. Study of the membrane protective potential of a combination of 2-ethyl-6-methyl-3hydroxypyridine succinate and citicoline preparations. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. 2018;118(1):18-22 (In Russ.).

29. Fedin AI. Diagnostics and treatment of chronic cerebral ischemia. Consilium medicum. 2016;18(2):8-12 (In Russ.).


For citation:


Shishkova V.N., Adasheva T.V. Chronic cerebral ischemia and headache in patients in primary care physician's practice. Neurology, Neuropsychiatry, Psychosomatics. 2021;13(1):131-137. (In Russ.) https://doi.org/10.14412/2074-2711-2021-1-131-137

Views: 18


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2074-2711 (Print)
ISSN 2310-1342 (Online)