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New possibilities of siponimod therapy in patients with secondary progressive multiple sclerosis

https://doi.org/10.14412/2074-2711-2021-1-138-144

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Abstract

The process of neurodegeneration in multiple sclerosis (MS) remains an urgent problem of modern neurology; from the point of view of its therapy, it is especially important to identify this condition during the transition to secondary progression. This paper reflects the opinion of the Council of Leading MS Experts on the early detection of secondary progressive MS and its diagnostic tools, including the use of new online questionnaires. Special attention is paid to the concept of clinical progression verification using the indicator of the confirmed progression of disability and to the prospect for introducing siponimod (Kiendra® ) into clinical practice for the treatment of patients with secondary progressive MS.

About the Authors

D. S. Kasatkin
Yaroslavl State Medical University, Ministry of Health of Russia
Russian Federation
5, Revolutsionnaya St., Yaroslavl 150000


N. V. Khachanova
N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia
Russian Federation
1, Ostrovityanov St., Moscow 117997


V. M. Alifirova
Siberian State Medical University, Ministry of Health of Russia
Russian Federation
2, Moskovsky High Road, Tomsk 634050


A. N. Boyko
N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia; Federal Center of Brain and Neurotechnologies, Federal Biomedical Agency of Russia
Russian Federation

1, Ostrovityanov St., Moscow 117997

Department of Neuroimmunology 



K. Z. Bakhtiyarova
Bashkir State Medical University, Ministry of Health of Russia
Russian Federation
3; Lenin St., Ufa 450008


Ya. V. Vlasov
Samara State Medical University, Ministry of Health of Russia
Russian Federation
89, Chapaevskaya St., Samara 443099


M. V. Davydovskaya
N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia; Research and Practical Center for Clinical and Economic Analysis, Ministry of Health of the Moscow Region
Russian Federation

1, Ostrovityanov St., Moscow 117997

4, Karbyshev St., Liter a, Krasnogorsk, Moscow Region 143033

 



E. P. Evdoshenko
City Clinical Hospital Thirty-One
Russian Federation
City Center for Multiple Sclerosis
3, Dynamo Pr., Saint Petersburg 197110


S. A. Sivertseva
AO «Neftyanik» Primary Healthcare Unit, Tyumen Regional Center for Multiple Sclerosis
Russian Federation
12, Schiller St., Tyumen 625048


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For citation:


Kasatkin D.S., Khachanova N.V., Alifirova V.M., Boyko A.N., Bakhtiyarova K.Z., Vlasov Y.V., Davydovskaya M.V., Evdoshenko E.P., Sivertseva S.A. New possibilities of siponimod therapy in patients with secondary progressive multiple sclerosis. Neurology, Neuropsychiatry, Psychosomatics. 2021;13(1):138-144. (In Russ.) https://doi.org/10.14412/2074-2711-2021-1-138-144

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ISSN 2074-2711 (Print)
ISSN 2310-1342 (Online)