A change in the parameters of P300 evoked potentials in relation to the degree of exacerbation of pain syndrome
https://doi.org/10.14412/2074-2711-2012-383
Abstract
In chronic pain, the state of suprasegmental brain structures (the cortex, limbic system, truncodiencephalic structures, which form the motivational-affective and cognitive components of pain behavior), actively affects pain afferentation as well. The purpose of the study was to comparatively analyze the parameters and topographic distribution of P300 cognitive evoked potential in patients with lower back pain. Sixty patients aged 22 to 60 years were examined. The authors made their clinical and neurological examinations, collected medical history data, and assessed back pain intensity by a visual analog scale. The findings were compared with the parameters of cognitive evoked potentials (the separating of P300 to count; keystroke in the recognition of significant stimuli; elaboration of a verbal and nonverbal visual stimulation protocol, by using emotionally significant stimuli). The processes of recognition and differentiation, those of directed attention, and the rate of information processing slowed down in patients with different stages of pain syndrome. The P300 separating procedure using the emotionally significant stimuli allows one to assess the specific features of chronization of pain syndromes and the presence of pain memory in the central nervous system of such patients. The estimation of P300 parameters over time or during treatment are of particular value for the optimization and evaluation of its efficiency.
References
1. <div><p>Gureje O., Simon G.E., von Korff M. A cross-national study of the course of persistent pain in primary care. Pain 2001;92:195—200.</p><p>Rubin D.I. Epidemiology and risk factors for spine pain. Neurol Clin 2007;25:353—71.</p><p>Hart R.P., Martelli M.F., Zasler N.D. Chronic pain and neuropsychological functioning. Neuropsychol Rev 2000;10:131—49.</p><p>Hart R.P., Wade J.B., Martelli M.F. Cognitive impairment in patient with chronic pain: significance of stress. Cur Pain Head reports 2003;7:116—226.</p><p>McCracken L.M., Iverson G.L. Predicting complaints of impaired cognitive functioning in patients with chronic pain. J Pain Symptom Manage 2001;21(5):392—6.</p><p>Nicholson K. Pain, cognition, and traumatic brain injury. Neurorehabilitation 2000;14:95—103.</p><p>Severeijns R., Vlaeyen J.W., van den Hout M.A. et al. Pain catastrophizing predicts pain intensity, disability, and psychological distress independent of. the level of physical impairment. Clin J Pain 2001;17:165—72.</p><p>Tyrer S.P. Repetitive strain injury. Pain linked to repetitive work. BMJ 1994;22(308):269—70.</p><p>Airaksinen O., Brox J., Cedraschi C. European guidelines for the management of chronic nonspecific low back pain. Eur Spine J 2006;15(2):192—300.</p><p>Aronoff G.M., Feldman J.B. Preventing disability from chronic pain: a review and reappraisal. Int Rev Psychiatry 2000;12(2):157—70.</p><p>Raldeman S. Modern Development in the Principles and Practice of Chiropractic. N. Y.: Appleton-CenturyCrofts, 1980; 94.</p><p>May A. Chronic pain may change the structure of the brain. Pain 2008;137(1):7—15.</p><p>Apkarian A.V., Bushnell M.C., Treede R.D. et al. Human brain mechanisms of pain perception and regulation in health and disease. Eur J Pain 2004;9:463—84.</p><p>Иваничев Г. А. Миофасциальная боль. Казань, 2007; 392 c.</p><p>Кукушкин М. Л. Механизмы хронизации болевых синдромов. Патогенез 2005;1:16—7.</p><p>Heller W. Neuropsychological mechanisms of individual differences in emotion, personality, and arousal. Neuropsychology 1993;7(4):476—89.</p></div><br />
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For citations:
Rachin AP, Averchenkova AA. A change in the parameters of P300 evoked potentials in relation to the degree of exacerbation of pain syndrome. Nevrologiya, neiropsikhiatriya, psikhosomatika = Neurology, Neuropsychiatry, Psychosomatics. 2012;4(2):52-55. (In Russ.) https://doi.org/10.14412/2074-2711-2012-383
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