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The features of the pathogenesis and clinical picture of Parkinson's disease that has developed in essential tremor

https://doi.org/10.14412/2074-2711-2019-3-94-98

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Abstract

In the past decades, there has been evidence on the relationship between Parkinson's disease (PD) and essential tremor (ET). In addition, PD frequently develops in already existing ET. The occurrence of PD in ET seems to be a problem of relevance, since the risk of PD is higher in patients with ET than that in the population. However, due to the lack of awareness about this nosological phenomenon among physicians, it can be difficult to formulate a diagnosis of PD that has developed in ET.

This paper gives an update on the clinical, epidemiological, pathogenetic, and neuroimaging characteristics of ET concurrent with PD. 

About the Authors

A. V. Kudrevatykh
Institute of Experimental Medicine; Acad. I.P. Pavlov First Saint Petersburg State Medical University, Ministry of Health of Russia
Russian Federation

12, Academician Pavlov St., Saint Petersburg 197376;

6/8, Lev Tolstoy St., Saint Petersburg 197089



I. V. Miliukhina
Institute of Experimental Medicine; Acad. I.P. Pavlov First Saint Petersburg State Medical University, Ministry of Health of Russia
Russian Federation

12, Academician Pavlov St., Saint Petersburg 197376;

6/8, Lev Tolstoy St., Saint Petersburg 197089



References

1. Critchley E. Clinical manifestations of essential tremor. J Neurol Neurosurg Psychiatry. 1972 Jun;35(3):365-72.

2. Arkadir D, Louis E. The balance and gait disorder of essential tremor: what does this mean for patients? Ther Adv Neurol Disord. 2013 Jul; 6(4):229-36. doi: 10.1177/1756285612471415.

3. Chunling W, Zheng X. Review on clinical update of essential tremor. Neurol Sci. 2016 Apr;37(4):495-502. doi: 10.1007/s10072-015-2380-1. Epub 2016 Jan 9.

4. Smeltere L, Kuznecovs V, Erts R. Depression and social phobia in essential tremor and Parkinson's disease. Brain Behav. 2017 Aug 2;7(9): e00781. doi: 10.1002/brb3.781. eCollection 2017 Sep.

5. Teive HA. Essential tremor: phenotypes. Parkinsonism Relat Disord. 2012 Jan;18 Suppl 1: S140-2. doi: 10.1016/S1353-8020(11)70044-X.

6. Hornabrook RW, Nagurney JT. Essential tremor in Papua, New Guinea. Brain. 1976 Dec;99(4):659-72.

7. Rajput AH, Rozdilsky B, Ang L, Rajput A. Significance of Parkinsonian Manifestations in Essential Tremor. Can J Neurol Sci. 1993 May;20(2):114-7.

8. Thenganatt MA, Jankovic J. The relationship between essential tremor and Parkinson's disease. Parkinsonism Relat Disord. 2016 Jan;22 Suppl 1: S162-5. doi: 10.1016/j.parkreldis.2015.09.032. Epub 2015 Oct 9.

9. Benito-Leon J, Louis E, Bermejo-Pareja F. Risk of incident Parkinson's disease and parkinsonism in essential tremor: a population based study. J Neurol Neurosurg Psychiatry. 2009 Apr; 80(4):423-5. doi: 10.1136/jnnp.2008.147223.

10. Dogu O, Sevim S, Camdeviren H et al. Prevalence of essential tremor: Door-to-door neurologic exams in Mersin Province, Turkey. Neurology. 2003 Dec 23;61(12):1804-6.

11. Louis ED, Marder K, Cote L, et al. Prevalence of a history of shaking in persons 65 years of age and older: Diagnostic and functional correlates. Mov Disord. 1996 Jan;11(1):63-9.

12. Louis ED, Ferreira JJ. How common is the most common adult movement disorder? Update on the worldwide prevalence of essential tremor. Mov Disord. 2010 Apr 15;25(5):534-41. doi: 10.1002/mds.22838.

13. Sveinbjornsdottir S. The clinical symptoms of Parkinson's disease. J Neurochem. 2016 Oct; 139 Suppl 1:318-324. doi: 10.1111/jnc.13691. Epub 2016 Jul 11.

14. Minen M, Louis E. Emergence of Parkinson's disease in essential tremor: A study of the clinical correlates in 53 patients. Mov Disord. 2008 Aug 15;23(11):1602-5. doi: 10.1002/mds.22161.

15. Sprenger FS, Wurster I, Seppi K, et al. Substantia nigra hyperechogenicity and Parkinson's disease risk in patients with essential tremor. Mov Disord. 2016 Apr;31(4):579-83. doi: 10.1002/mds.26515. Epub 2016 Feb 19.

16. Wider C, Ross OA, Wszolek ZK. Genetics of Parkinson disease and essential tremor. Curr Opin Neurol. 2010 Aug;23(4):388-93. doi: 10.1097/WCO.0b013e32833b1f4c.

17. Unal Gulsuner H, Gulsuner S, Mercan FN, et al. Mitochondrial serine protease HTRA2 p.G399S in a kindred with essential tremor and Parkinson disease. Proc Natl Acad Sci U S A. 2014 Dec 23;111(51):18285-90. doi: 10.1073/pnas.1419581111. Epub 2014 Nov 24.

18. Chao YX, Ng EY, Tan L, et al. Lrrk2 R1628P variant is a risk factor for essential tremor. Sci Rep. 2015 Mar 12;5:9029. doi: 10.1038/srep09029.

19. Tan EK, Matsuura T, Nagamitsu S, et al. Polymorphism of NACP-Rep1 in Parkinson's disease: an etiologic link with essential tremor? Neurology. 2000 Mar 14;54(5):1195-8.

20. Ryu DW, Lee SH, Oh YS, et al. Clinical Characteristics of Parkinson's Disease Developed from Essential Tremor. J Parkinsons Dis. 2017; 7(2):369-376. doi: 10.3233/JPD-160992.

21. Rana AQ, Qureshi A, Rana M, et al. Prevalence of essential tremor in an idiopathic Parkinson's disease patient population. Int J Neurosci. 2015 Apr;125(4):253-5. doi: 10.3109/00207454.2014.929128. Epub 2014 Jun 25.

22. Shahed J, Jankovic J. Exploring the relationship between essential tremor and Parkinson's disease. Parkinsonism Relat Disord. 2007 Mar;13(2):67-76. Epub 2006 Aug 2.

23. Elble R. Essential tremor is a monosymptomatic disorder. Mov Disord. 2002 Jul;17(4):633-7.

24. Simoes RM, Constantino A, Gibadulina E, et al. Examining the Motor Phenotype of Patients with Both Essential Tremor and Parkinson's Disease. Tremor Other Hyperkinet Mov (N Y). 2012;2. pii: tre-02-47-149-3. doi: 10.7916/D8CN72N0. Epub 2012 May 21.

25. Louis ED, Wise A, Alcalay RN, et al. Essential tremor-Parkinson's disease: A double whammy. J Neurol Sci. 2016 Jul 15;366:47-51. doi: 10.1016/j.jns.2016.04.040. Epub 2016 Apr 23.

26. Ozen Barut B, Gunal D, Turkmen В, et al. Clinical and cognitive profiles of patients with both Parkinson's disease and essential tremor. Acta Neurol Belg. 2013 Jun;113(2):117-25. doi: 10.1007/s13760-012-0124-z. Epub 2012 Aug 28.

27. Wurster I, Abaza A, Brockmann K, et al. Parkinson's disease with and without preceding essential tremor-similar phenotypes: a pilot study. J Neurol. 2014 May;261(5):884-8. doi: 10.1007/s00415-014-7285-z. Epub 2014 Mar 4.

28. Arabia G, Lupo A, Manfredini L, et al. Clinical, electrophysiological, and imaging study in essential tremor-Parkinson's disease syndrome. Parkinsonism Relat Disord. 2018 Nov;56:20-26. doi: 10.1016/j.parkreldis.2018.06.005. Epub 2018 Jun 5.

29. Ghika A, Kyrosis A, Potagas C, Louis ED. Motor and Non-motor Features: Differences between Patients with Isolated Essential Tremor and Patients with Both Essential Tremor and Parkinson's Disease. Tremor Other Hyperkinet Mov (N Y). 2015 Aug 14;5:335. doi: 10.7916/D83777WK. eCollection 2015.

30. Louis ED, Rohl B, Collins K, Cosentino S. Poorer Cognitive Performance in Patients with Essential Tremor-Parkinson's Disease vs. Patients with Parkinson's Disease. Front Neurol. 2015 May 18;6:106. doi: 10.3389/fneur.2015.00106. eCollection 2015.

31. Nodel' MR, Tsenteradze SL, Poluektov MG. REM-sleep behavior disorder and sleepwalking in a patient with Parkinson’s disease and essential tremor. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. 2017;117(12):88-94. (In Russ.).

32. Kudrevatykh AV, Didur MD, Sergeev TV, et al. Non-motor symptoms and quality of life in patients with essential tremor, Parkinson's disease and a combination of essential tremor and Parkinson's disease. Meditsinskii akademicheskii zhurnal. 2018;18(2):63-71. (In Russ.).

33. Milyukhina IV, Ermolenko EI, Ivanova AS, Suvorov AN. The role of gastrointestinal microbiota in the pathogenesis of Parkinson's disease. Nevrologicheskii zhurnal. 2017;22(6):280-6. (In Russ.).

34. Louis ED, Jurewicz EC. Olfaction in essential tremor patients with and without isolated rest tremor. Mov Disord. 2003 Nov;18(11):1387-9.

35. Applegate LM, Louis ED. Essential tremor: Mild olfactory dysfunction in a cerebellar disorder. Parkinsonism Relat Disord. 2005 Sep;11(6): 399-402.

36. Busenbark KL, Huber SJ, Greer G, et al. Olfactory function in essential tremor. Neurology. 1992 Aug;42(8):1631-2.

37. Quagliato LB, Viana MA, Quagliato EM, Simis S. Olfaction and essential tremor. Arq Neuropsiquiatr. 2009 Mar;67(1):21-4.

38. Louis ED, Faust PL, Vonsattel JP, et al. Neuropathological changes in essential tremor: 33 cases compared with 21 controls. Brain. 2007 Dec;130(Pt 12):3297-307. Epub 2007 Nov 19.

39. Braak H, Del Tredici K, Rü b U, et al. Staging of brain pathology related to sporadic Parkinson's disease. Neurobiol Aging. 2003 MarApr;24(2):197-211.

40. Louis ED, Honig LS, Vonsattel JP, et al. Essential tremor associated with focal nonnigral Lewy bodies: a clinicopathologic study. Arch Neurol. 2005 Jun;62(6):1004-7.

41. Clark LN, Louis ED. Essential tremor. Handb Clin Neurol. 2018;147:229-239. doi: 10.1016/B978-0-444-63233-3.00015-4.

42. Lauckaite K, Rastenyte D, Surkiene D, et al. Ultrasonographic (TCS) and clinical findings in overlapping phenotype of essential tremor and Parkinson's disease (ET-PD). BMC Neurol. 2014 Mar 22;14:54. doi: 10.1186/1471-2377-14-54.

43. Sharifi S, Nederveen AJ, Booij J, Rootselaar A. Neuroimaging essentials in essential tremor: A systematic review. Neuroimage Clin. 2014 May 9; 5:217-31. doi: 10.1016/j.nicl.2014.05.003. eCollection 2014.

44. Cao H, Wang FR, Luo BX, et al. VoxelBased Magnetic Resonance Imaging Morphometric Study of Cerebral and Cerebellar Gray Matter in Patients Under 65 Years with Essential Tremor. Med Sci Monit. 2018 May 13;24:3127-3135. doi: 10.12659/MSM.906437.

45. Caligiuri ME, Arabia G, Barbagallo G, Lupo A. Structural connectivity differences in essential tremor with and without resting tremor. J Neurol. 2017 Sep;264(9):1865-1874. doi: 10.1007/s00415-017-8553-5. Epub 2017 Jul 20.

46. Barbagallo G, Caligiuri M, Arabia G, et al. Structural connectivity differences in motor network between tremor-dominant and nontremor Parkinson's disease. Hum Brain Mapp. 2017 Sep;38(9):4716-4729. doi: 10.1002/hbm.23697. Epub 2017 Jun 20.

47. Lee MS, Kim YD, Im J, et al. 123I-IPT brain SPECT study in essential tremor and Parkinson's disease. Neurology. 1999 Apr 22;52(7): 1422-6. 48. Isaias IU, Canesi M, Benti R, et al. Striatal dopamine transporter abnormalities in patients with essential tremor. Nucl Med Commun. 2008 Apr;29(4):349-53. doi: 10.1097/MNM.0b013e3282f4d307.

48. Waln O, Wu Y, Perlman R, et al. Dopamine transporter imaging in essential tremor with and without parkinsonian features. J Neural Transm (Vienna). 2015 Nov;122(11):1515-21. doi: 10.1007/s00702-015-1419-z. Epub 2015 Jul 2.

49. Sabbahi M, Etnyre B, Al-Jawayed I, Jankovic J. H-Reflex Recovery Curves Differentiate Essential Tremor, Parkinson's Disease, and the Combination of Essential Tremor and Parkinson's Disease. J Clin Neurophysiol. 2002 Jun;19(3):245-51.

50. Cohen O, Pullman S, Jurewicz E, et al. Rest Tremor in Patients With Essential Tremor. Arch Neurol. 2003 Mar;60(3):405-10.

51. Yavuz D, Gü ndü z A, Ertan S, et al. Specific brainstem and cortico-spinal reflex abnormalities in coexisting essential tremor and Parkinson's disease (ET-PD). Neurophysiol Clin. 2015 May;45(2):143-9. doi: 10.1016/j.neucli.2015.01.001. Epub 2015 Apr 16.


For citation:


Kudrevatykh A.V., Miliukhina I.V. The features of the pathogenesis and clinical picture of Parkinson's disease that has developed in essential tremor. Neurology, Neuropsychiatry, Psychosomatics. 2019;11(3):94-98. (In Russ.) https://doi.org/10.14412/2074-2711-2019-3-94-98

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ISSN 2074-2711 (Print)
ISSN 2310-1342 (Online)