Атеротромботический инсульт при неклапанной фибрилляции предсердий

В обзоре анализируются данные о частоте выявления, возможностях прогнозирования и профилактики некардиоэмболических инсультов при неклапанной фибрилляции предсердий. Отмечено, что, согласно накопленным фактам, при неклапанной фибрилляции предсердий антагонисты витамина К уступают антиагрегантам в том, что касается эффективности профилактики некардиоэмболических (в частности, атеротромботических) инсультов, а широкое использование сочетания пероральных антикоагулянтов с антиагрегантами в целом не способствует снижению частоты неблагоприятных исходов, заметно увеличивая риск серьезных кровотечений. Тем не менее не исключено, что подобная комбинированная антитромботическая терапия сможет оказаться полезной отдельным категориям больных с наиболее высоким риском атеротромботического инсульта и относительно невысокой опасностью геморрагических осложнений. Контингенты больных, у которых разумно рассматривать подобный подход, пока не определены.

инсульт, ишемический инсульт, некардиоэмболический инсульт, атеротромботический инсульт, фибрилляция предсердий, пероральные антикоагулянты, ацетилсалициловая кислота

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