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Pathogenesis, clinical features, and treatments of depression in Parkinson's disease

https://doi.org/10.14412/2074-2711-2019-2-93-99

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Abstract

Depression is the most common non-motor manifestation of Parkinson's disease (PD), which significantly affects the rate of disease progression and increases the risk of motor complications and dementia. The paper considers the etiology and pathogenesis, cause-and-effect factors of depression in PD, and features of its diagnosis and treatment. Attention is paid to the algorithm for a physician's actions in the detection of depressive disorder in a patient with PD, to the choice of an antidepressant, and to the promising areas of therapy.

About the Author

I. V. Milyukhina
Institute of Experimental Medicine; Acad. I.P. Pavlov First Saint Petersburg State Medical University, Ministry of Health of Russia
Russian Federation

Irina Valentinovna Milyutina

12, Academician Pavlov St., Saint Petersburg 197376, 6/8, Lev Tolstoy St., Saint Petersburg 197089



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For citation:


Milyukhina I.V. Pathogenesis, clinical features, and treatments of depression in Parkinson's disease. Neurology, Neuropsychiatry, Psychosomatics. 2019;11(2):93-99. (In Russ.) https://doi.org/10.14412/2074-2711-2019-2-93-99

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ISSN 2074-2711 (Print)
ISSN 2310-1342 (Online)