Preview

Neurology, Neuropsychiatry, Psychosomatics

Advanced search

THERAPY FOR EPILEPSY IN MIDDLE-AGED AND ELDERLY PATIENTS

https://doi.org/10.14412/2074-2711-2009-25

Full Text:

Abstract

The authors consider the specific features of epilepsy in middle-aged and elderly patients: a preponderance of focal symptomatic and cryptogenic epilepsies, a frequent combination with concomitant mental and somatic diseases, and a relative efficacy of small-dose antiepileptic drugs (AED). Choice of therapy is noted to depend on the form of epilepsy/type of seizures, comorbidity and used medicines. A major focus is on the use of basic AEDs R carbamazepine and valproates. Data on the promise for using depakine chronosphere in middle-aged and elderly patients are given.

About the Authors

P. N. Vlasov
Moscow State Medical University of Dentistry
Russian Federation


O. V. Andreeva
Moscow State Medical University of Dentistry
Russian Federation


References

1. <div><p>Hauser W.A., Annegers J.F., Kurland L.T. Incidence of epilepsy and unprovoked seizures in Rochester, Minnesota: 1935-1984. Epilepsia 1993;34:453-68.</p><p>Власов П.Н. Клиническая фармакология лекарственных средств, применяемых при судорожном синдроме. В кн: Клиническая фармакология. Национальное руководство.</p><p>Национальный проект «Здоровье». М.: Геотар-Медиа, 2008;882.</p><p>Власов П.Н. Алгоритмы диагностики и терапии эпилепсии у взрослых в поликлинических условиях. Фарматека 2006;7:96-104.</p><p>Зенков Л.Р. Как улучшить лечение эпилепсии в России. РМЖ 2003;1:8.</p><p>Карлов В.А. Стратегия и тактика терапии эпилепсии сегодня. Невропатол и психиатр 2004;8:28-34.</p><p>Мухин К.Ю., Петрухин А.С. Эпилептические синдромы. Диагностика и стандарты терапии (справочное руководство). М., 2005;143 с.</p><p>Dulac O. and Alvarez J.-Claude.</p><p>Bioequivalence of a new sustained-release formulation of sodium valproate, valproate modified-release granules, compared with existing sustained-release formulations after once- , or twice-daily administration. Pharmacotherapy 2005;25(1):35-42. 8.</p><p>The epilepsies: the diagnosis and management of the epilepsies in adults and children in primary and secondary care. Clinical guideline 20.</p><p>NICE. London, 2004;73 p.</p><p>Glauser T. , Ben-Menachem E., Bourgeois B. et al. ILAE treatment guidelines: evidence-based analysis of antiepileptic drug efficacy and effectiveness as initial monotherapy for epileptic seizures and syndromes. Epilepsia 2006;47:1094-120.</p><p>Karceski S., Morrell M., Carpenter D. Treatment of epilepsy in adults: expert opinion. Epilepsy&amp;Behavior 2005;1-64.</p><p>Sillanpaa M. Carbamazepine. The treatment of epilepsy. Second edition. 2004. Shorvon S., Perucca E., Fish D. et al. Blackwell science 345-57.</p><p>Власов П.Н. Дифференциальная диагностика основных пароксизмальных состояний в практике невролога и терапевта. Фарматека 2008;5:91-4.</p></div><br />


For citation:


Vlasov P.N., Andreeva O.V. THERAPY FOR EPILEPSY IN MIDDLE-AGED AND ELDERLY PATIENTS. Neurology, Neuropsychiatry, Psychosomatics. 2009;1(1):54-58. (In Russ.) https://doi.org/10.14412/2074-2711-2009-25

Views: 348


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2074-2711 (Print)
ISSN 2310-1342 (Online)