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Insomnia in patients with migraine

https://doi.org/10.14412/2074-2711-2019-2-22-29

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Abstract

Objective: to evaluate the significance of insomnia and chronobiological patterns in the development of headache (HA) attacks for the formation of clinical features of migraine and for the elaboration of strategies for its prevention.

Patients and methods. A prospective comparative study was conducted in 60 patients aged 18–65 years who were diagnosed as having migraine (with or without aura) with comorbid sleep disorder. Group 1 consisted of 30 patients with migraine and insomnia; Group 2 comprised 30 patients with migraine without insomnia. The study participation included four visits to a physician for 12 months.

Results and discussion. Persistent sleep disorders in patients with migraine were shown to worsen the course of the underlying disease: HA attacks had a greater intensity, mainly left-sided localization and a longer duration. Group 1 patients were observed to have a chronic course of the disease with a frequency of ≥8 attacks per month in 33% of cases. Analysis of biological rhythms revealed that individuals with evening and mildly evening chronotypes were characterized by the greatest changes in the sleep-wake cycle, by sleep deprivation and its reduced efficiency. Analysis of the data of HA and sleep diaries kept by the patients for 12 months showed that Group 1 had four peaks of the daily distribution of HA attacks; 13.4% of attacks occurred during sleep and early morning.

Conclusion. The coexistence of sleep disorders and HA is not only manifested as the overlapping of clinical manifestation, but also largely determines their natural course and prognosis, i.e. their progression into a chronic form. Therefore, it is imperative to identify sleep disorders in migraines, since their correction is effective and, in most cases, allows chronic HA to progress to an episodic form.

About the Authors

E. M. Evdokimova
I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia
Russian Federation

Elena Mikhailovna Evdokimova

Department of Nervous System Diseases and Neurosurgery, Faculty of General Medicine

11, Rossolimo St., Build. 1, Moscow 119021



G. R. Tabeeva
I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia
Russian Federation

Department of Nervous System Diseases and Neurosurgery, Faculty of General Medicine

11, Rossolimo St., Build. 1, Moscow 119021



References

1. Steiner TJ,Stovner LJ, Vos T. GBD 2015: Migraine is the third cause of disability in under 50s. J Headache Pain. 2016 Dec;17(1):104. Epub 2016 Nov 14.

2. Tabeeva GR. Chronobiology of migraine. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. 2010;110;4(1):104-12. (In Russ.).

3. Bigal ME, Lipton RB. What predicts the change from episodic to chronic migraine? Curr Opin Neurol. 2009 Jun;22(3):269-76. doi: 10.1097/WCO.0b013e32832b2387.

4. Peres MF. Melatonin, the pineal gland and their implications for headache disorders. Cephalalgia. 2005;25(6):403-11. doi:10.1111/j.1468-2982.2005.00889.x

5. Engstr∅m M, Hagen K, Bj∅rk M, et al. Sleep-related and non-sleep-related migraine: interictal sleep quality, arousals and pain Thresholds. J Headache Pain. 2013 Aug 6;14:68. doi: 10.1186/1129-2377-14-68.

6. Paiva T., Batista A., Martins P., & Martins A. The Relationship Between Headaches and Sleep Disturbances. Headache: The Journal of Head and Face Pain, 1995, 35(10), 590–596. doi:10.1111/j.1526-4610.1995.hed3510590.x

7. Morgan I, Fransisco E, Bizu G. Sleep disturbances and quality of life in Sub-Saharan African migraineurs. J Headache Pain. 2015 Mar 4;16:18. doi: 10.1186/s10194-015-0504-x.

8. Hasler G, Byusse DJ, Gamma A, et al. Excessive daytime sleepiness in young adults: a 20-year prospective community study. J Clin Psychiatry. 2005 Apr;66(4):521-9.

9. Carscadon MA. Evaluation of excessive daytime sleepiness. Neurophysiol Clin. 1993 Jan; 23(1):91-100.

10. Refinetti R. Circadian physiology. New York: Taylor and Francis; 2006.

11. Headache Classification Committee of the International Headache Society (IHS). The International Classification of Headache Disorders. 3rd edition (beta version). Cephalalgia. 2013 Jul;33(9):629-808. doi: 10.1177/0333102413485658.

12. American Academy of Sleep Medicine. International classification of sleep disorders, 3rd edn. Darien, IL: American Academy of Sleep Medicine, 2014

13. Horne JA, Ostberg O. A self-assessment questionnaire to determine morningness– eveningness in human circadian rhythms. Int J Chronobiol. 1976;4(2):97-110.

14. Giglio LM, Magalhaes PV, Andreazza AC, et al. Development and use of a biological rhythm interview. J Affect Disord. 2009 Nov; 118(1-3):161-5. doi: 10.1016/j.jad.2009.01.018. Epub 2009 Feb 20.

15. Tabeeva GR, Yakhno NN. Migren' [Migraine]. Moscow: GEOTAR-Media; 2011. 624 p.

16. Poluektov MG. Melatonin and sleep–wake disorders. Spravochnik poliklinicheskogo vracha. 2012;(3):1-4. (In Russ.).

17. Roenneberg T, Kuehnle T, Pramstaller PP, et al. A marker for the end of adolescence. Curr Biol. 2004;14(24):R1038-9. doi: 10.1016/j.cub.2004.11.039

18. Alstadhaug KB, Salvesen R, Bekkelung S. 24-hour distribution of migraine. Headache. 2008 Jan;48(1):95-100. doi: 10.1111/j.15264610.2007.00779.x.

19. Dexter JD, Riley TL. Studies in nocturnal migraine. Headache. 1975 Apr;15(1):51-62.

20. Torelli P, Cologno D, Manzoni GC. Weekend headache: A possible role of work and life-style. Headache. 1999 Jun;39(6):398-408.

21. Osterman PO, Lundberg PO, Lundquist S, et al. Weekly periodicity of headache and the effect of changes in weather on headache. Ups J Med Sci Suppl. 1980;31:23-6. doi:10.1007/bf02184436

22. Torelli P, Cologno D, Manzoni GC. Weekend headache: a retrospective study in migraine without aura and episodic tensiontype headache. Headache. 1999 Jan;39(1):11-20.

23. Brewerton TD, Mark SC. A study of the seasonal variation in migraine. Headache. 1990 Jul;30(8):511-3.

24. Claustrat B, Brun J, Chiquet C, et al. Melatonin secretion is supersensitive to light in migraine. Cephalalgia. 2004 Feb;24(2):128-33.


For citation:


Evdokimova E.M., Tabeeva G.R. Insomnia in patients with migraine. Neurology, Neuropsychiatry, Psychosomatics. 2019;11(2):22-29. (In Russ.) https://doi.org/10.14412/2074-2711-2019-2-22-29

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ISSN 2074-2711 (Print)
ISSN 2310-1342 (Online)