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Patent foramen ovale and embolic cryptogenic stroke

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The paper considers the actual problem of cryptogenic stroke and patent foramen ovale (PFO). It highlights the issues of pathogenesis and role of paradoxical embolism in the development of cerebral circulation disorders. The features of clinical manifestations and neuroimaging pattern of stroke in the presence of PFO are described. Ultrasound diagnostic techniques used to verify a cardiac anomaly are characterized. Approaches to establishing a cause-and-effect relationship between the presence of PFO and the development of stroke are presented. The current possibilities of secondary prevention in this category of patients, in particular the results of studies of percutaneous PFO occlusion, are discussed.

About the Authors

A. A. Kulesh
Acad. E.A. Vagner Perm State Medical University, Ministry of Health of Russia
Russian Federation

Aleksey Aleksandrovich Kulesh

26, Petropavlovskaya St., Perm 614990

V. V. Shestakov
Acad. E.A. Vagner Perm State Medical University, Ministry of Health of Russia
Russian Federation

26, Petropavlovskaya St., Perm 614990


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Kulesh A.A., Shestakov V.V. Patent foramen ovale and embolic cryptogenic stroke. Neurology, Neuropsychiatry, Psychosomatics. 2019;11(2):4-11. (In Russ.)

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