Ортостатическая гипотензия как модифицируемый фактор риска развития когнитивных нарушений: обзор литературы

Возраст-ассоциированные заболевания становятся важной проблемой общественного здравоохранения в связи с увеличением числа людей пожилого и старческого возраста во всем мире. В этой возрастной группе велика распространенность недементных когнитивных нарушений (КН) и деменции, что определяет значительное ухудшение качества жизни. Одним из возможных факторов риска развития КН и деменции является ортостатическая гипотензия (ОГ), также часто выявляемая в пожилом и старческом возрасте. Представлен обзор публикаций, посвященных определению связи ОГ с риском развития КН/деменции у пациентов старших возрастных групп. Хотя результаты исследований противоречивы, в ряде работ и метаанализе указано на связь между ОГ и КН/деменцией у больных пожилого и старческого возраста. Своевременная диагностика ОГ позволит не только выявлять группы высокого риска в отношении развития КН и/или деменции, но и вовремя проводить профилактические мероприятия для снижения этого риска.

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