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The modern concept of cognitive reserve

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The main forms of cognitive impairment (CI) are characterized by a significant variability in the relationship between morphological changes and clinical manifestations. One of the promising concepts, which explains these features, is a modern model of cognitive reserve. The cognitive reserve concept that is most widely used in the context of dementia is often employed to explain the mechanisms, by which the functional systems of the brain resist neuropathological changes. The mechanisms that ensure cognitive reserve function in the health and disease of the brain are to activate its neuronal connections. Therefore, individuals with more efficient neuronal connections and an ability to form alternative neural networks and, accordingly, to create cognitive strategies in response to increased cognitive load are characterized by greater cognitive reserve. The modern concept of cognitive reserve opens up prospects for explaining the causes and mechanisms of development of CI and also justifies the possibilities of using alternative strategies for their correction.

About the Authors

N. N. Koberskaya
I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia
Russian Federation

Nadezhda Nikolaevna Koberskaya

Department of Nervous System Diseases and Neurosurgery, Faculty of General Medicine

11, Rossolimo St., Build. 1, Moscow 119021

G. R. Tabeeva
I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia
Russian Federation

Department of Nervous System Diseases and Neurosurgery, Faculty of General Medicine

11, Rossolimo St., Build. 1, Moscow 119021


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For citation:

Koberskaya N.N., Tabeeva G.R. The modern concept of cognitive reserve. Neurology, Neuropsychiatry, Psychosomatics. 2019;11(1):96-102. (In Russ.)

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