Preview

Neurology, Neuropsychiatry, Psychosomatics

Advanced search

Social support and stroke risk: an epidemiological study of a population aged 25–64 years in Russia/Siberia (the WHO MONICA-psychosocial program)

https://doi.org/10.14412/2074-2711-2019-1-12-20

Full Text:

Abstract

Objective: to determine the impact of social support on the risk of stroke in an open population aged 25–64 years in Russia/Siberia.

Patients and methods. A random representative sample of a Novosibirsk population aged 25–64 years (657 men; mean age, 44.3±0.4 years; response rate, 82.1%; 689 women; mean age, 45.4±0.4 years; response rate, 72.5%) was examined within Screening III of the WHO MONICApsychological program. The screening program included: registration of sociodemographic data and determination of social support (the index of close contacts (ICC) and the social network index (SNI). The prospective follow-up study period was 16 years. The study identified the following end-point: new-onset stroke cases.

Results and discussion. The open population aged 25–64 years showed a low ICC in 62% of men and in 56.8% of women (χ2=22.603; df=2; p=0.0001) and a low SNI in 43.5% of men and in 33.9% of women (χ2=21.546; df=2; p=0.0001). During a 16-year follow-up, the risk of stroke in the people with a low ICC was 3.5 times higher for men (95% confidence interval (CI), 1.42–7.69; p<0.05), and that was 3.6 times higher for women (95% CI, 1.5–8.7; p<0.01). Over the same follow-up period, the risk of stroke in the patients having a low SNI was 3.4-fold higher for men (95% CI 1.28–5.46, p<0.001) and 2.3-fold higher for women (95% CI 1.18–4.49, p<0.05). Application of a multivariate model revealed an increase in the risk of stroke in people with a low level of social support: in men with an unfavorable family status, manual labor and in women with a low level of education.

Conclusion. Social support is a protective risk factor for stroke in both men and women.

About the Authors

A. V. Gafarova
Research Institute of Internal and Preventive Medicine, Branch, Federal Research Center Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences;
Russian Federation
175/1, B. Bogatkov St., Novosibirsk 630089


E. A. Gromova
Research Institute of Internal and Preventive Medicine, Branch, Federal Research Center Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences;
Russian Federation
175/1, B. Bogatkov St., Novosibirsk 630089


D. О. Panov
Research Institute of Internal and Preventive Medicine, Branch, Federal Research Center Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences;
Russian Federation
175/1, B. Bogatkov St., Novosibirsk 630089


I. V. Gagulin
Research Institute of Internal and Preventive Medicine, Branch, Federal Research Center Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences;
Russian Federation
175/1, B. Bogatkov St., Novosibirsk 630089


E. A. Krymov
Research Institute of Internal and Preventive Medicine, Branch, Federal Research Center Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences;
Russian Federation
175/1, B. Bogatkov St., Novosibirsk 630089


V. V. Gafarov
Research Institute of Internal and Preventive Medicine, Branch, Federal Research Center Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences;
Russian Federation

Valery Vasilyevich Gafarov

175/1, B. Bogatkov St., Novosibirsk 630089



References

1. Go AS, Mozaffarian D, Roger VL, et al. Heart disease and stroke statistics-2014 update: a report from the American Heart Association. Circulation. 2014 Jan 21;129(3):e28-e292. doi: 10.1161/01.cir.0000441139.02102.80. Epub 2013 Dec 18.

2. Everson-Rose SA, Lewis TT. Psychosocial factors and cardiovascular diseases. Annu Rev Public Health. 2005;26:469-500. doi: 10.1146/annurev.publhealth.26.021304.144542

3. Arthur HM. Depression, isolation, social support, and cardiovascular disease in older adults. J Cardiovasc Nurs. 2006 Sep-Oct;21 (5 Suppl 1):S2-7; quiz S8-9.

4. Berkman LF, Glass T, Brissette I, Seeman TE. From social integration to health: Durkheim in the new millennium. Soc Sci Med. 2000 Sep; 51(6):843-57.

5. Andrе-Petersson L, Hedblad B, Janzon L, Еstergren PO. Social support and behavior in a stressful situation in relation to myocardial infarction and mortality: who is at risk? Results from prospective cohort study «Men born in 1914,» Malmö , Sweden. Int J Behav Med. 2006; 13(4):340-7. doi: 10.1207/s15327558ijbm1304_9

6. Cene CW, Loehr L, Lin FC, et al. Social isolation, vital exhaustion, and incident heart failure: findings from the Atherosclerosis Risk in Communities Study. Eur J Heart Fail. 2012 Jul;14(7):748-53. doi: 10.1093/eurjhf/hfs064. Epub 2012 May 14.

7. Rutledge T, Linke SE, Olson MB, et al. Social networks and incident stroke among women with suspected myocardial ischemia. Psychosom Med. 2008 Apr;70(3):282-7. doi: 10.1097/PSY.0b013e3181656e09. Epub 2008 Mar 31.

8. Ikeda A, Iso H, Kawachi I, et al. Social support and stroke and coronary heart disease: the JPHC study cohorts II. Stroke. 2008 Mar;39(3): 768-75. doi: 10.1161/STROKEAHA.107.496695. Epub 2008 Jan 31.

9. Loucks EB, Sullivan LM, D'Agostino RB, et al. Social networks and inflammatory markers in the Framingham Heart Study. J Biosoc Sci. 2006 Nov;38(6):835-42. Epub 2006 Jan 27.

10. Stuller KA, Jarrett B, DeVries AC. Stress and social isolation increase vulnerability to stroke. Exp Neurol. 2012 Jan;233(1):33-9. doi: 10.1016/j.expneurol.2011.01.016. Epub 2011 Jan 28.

11. Nagayoshi M, Everson-Rose SA, Iso H, et al. Social Network, Social Support, and Risk of Incident Stroke: The Atherosclerosis Risk in Communities Study. Stroke. 2014 Oct;45(10): 2868-73. doi: 10.1161/STROKEAHA.114. 005815. Epub 2014 Aug 19.

12. MONICA Monograph and Multimedia Sourcebook. Helsinki; 2003.

13. Stringhini S, Berkman L, Dugravot A, et al. Socioeconomic status, structural and functional measures of social support, and mortality: The British Whitehall II Cohort Study, 1985-2009. Am J Epidemiol. 2012 Jun 15;175(12):1275-83. doi: 10.1093/aje/kwr461. Epub 2012 Apr 24.

14. Byuyul' A, Tsefel' P. SPSS: iskusstvo obrabotki informatsii. Analiz statisticheskikh dannykh i vosstanovlenie skrytykh zakonomernostei [SPSS: the art of information processing. Analysis of statistical data and the restoration of hidden patterns]. SaintPetersburg: DiaSoftYuP; 2015.

15. Glants K. Biomeditsinskaya statistika [Biomedical statistics]. Moscow: Praktika; 1998. 459 p.

16. Cox DR. Regression Models and Life Tables. Journal of the Royal Statistical Society Series B. 1972;34:187-220.

17. Valtorta NK, Kanaan M, Gilbody S, et al. Loneliness and social isolation as risk factors for coronary heart disease and stroke: systematic review and meta-analysis of longitudinal observational studies. Heart. 2016 Jul 1;102(13): 1009-16. doi: 10.1136/heartjnl-2015-308790. Epub 2016 Apr 18.

18. Gafarov V, Panov D, Gromova E, et al. Low social support as predictor of long-term risk of stroke in female population in Russia: MONICA-psychosocial epidemiological study. Eur J Intern Med. 2013;24(1):e47.

19. Soulsby LK, Bennett KM. Marriage and Psychological Wellbeing: The Role of Social Support Department of Psychological Sciences. Psychology. 2015;6(11):1349-59. doi: 10.4236/psych.2015.611132

20. Olomu AB, Grzybowski M, Ramanath VS, et al. Evidence of disparity in the application of quality improvement efforts for the treatment of acute myocardial infarction: the American College of Cardiology's Guidelines Applied in Practice Initiative in Michigan. Am Heart J. 2010 Mar;159(3):377-84. doi: 10.1016/j.ahj.2009.12.014.


Review

For citations:


Gafarova A.V., Gromova E.A., Panov D.О., Gagulin I.V., Krymov E.A., Gafarov V.V. Social support and stroke risk: an epidemiological study of a population aged 25–64 years in Russia/Siberia (the WHO MONICA-psychosocial program). Neurology, Neuropsychiatry, Psychosomatics. 2019;11(1):12-20. https://doi.org/10.14412/2074-2711-2019-1-12-20

Views: 785


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2074-2711 (Print)
ISSN 2310-1342 (Online)