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Neurology, Neuropsychiatry, Psychosomatics

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Vol 12, No 5 (2020) The polymorphic variants DRD2 rs1800497 and ABCB1 3435C>T are associated with antipsychotic safety parameters in adolescents with an acute psychotic episode: the results of a pilot study Abstract  PDF (Eng)  similar documents
D. V. Ivashchenko, S. Z. Khoang, M. Kh. Tazagulova, B. V. Makhmudova, N. I. Buromskaya, P. V. Shimanov, R. V. Deitch, I. V. Dorina, M. I. Nastovich, K. A. Akmalova, A. A. Kachanova, E. A. Grishina, L. M. Savchenko, Yu. S. Shevchenko, D. A. Sychev
"... Rating Scale (BARS). The patients were genotyped for CYP3A4*22, CYP3A5*3, CYP2D6*4, *9, *10, ABCB1 1236C ..."
 
Vol 12, No 2 (2020) Pharmacogenetics of the safety of phenazepam in alcohol withdrawal syndrome: haplotype and combinatorial analyses of polymorphic variants in the pharmacokinetic factor genes Abstract  similar documents
D. V. Ivashchenko, O. V. Tereshchenko, I. I. Temirbulatov, K. A. Akmalova, E. A. Grishina, M. S. Zastrozhin, L. M. Savchenko, E. A. Bryun, D. A. Sychev
"... ABCB1 3435-12362677 and T-T-T-CYP3A5*3 isozymes (OR=5.03; 95% CI, 1.65–15.34; p=0.0056); T-T-T-CYP2C9 ..."
 
Vol 12, No 6 (2020) Efficacy and safety of antipsychotics in adolescents with an acute psychotic episode in relation to the activity of CYP3A and CYP2D6 isoenzymes Abstract  similar documents
D. V. Ivashchenko, A. S. Osipov, E. V. Nazarova, M. A. Ovchinnikova, N. I. Buromskaya, V. V. Smirnov, P. V. Shimanov, R. V. Deitch, T. A. Fainshtein, E. N. Shagovenko, K. A. Akmalova, A. A. Kachanova, E. A. Grishina, L. M. Savchenko, Yu. S. Shevchenko, D. A. Sychev
"... CYP3A4/5 and CYP2D6 metabolize most antipsychotics. The activity of these isoenzymes in children ..."
 
Vol 9, No 1S (2017): SPECIAL ISSUE: EPILEPSY The efficacy and safety of valproic acid medications with controlled active ingredient release in adults in real clinical practice from the position of pharmacokinetic and pharmacogenetic approaches Abstract  similar documents
P. N. Vlasov, N. V. Orekhova, M. V. Antonyuk, N. V. Filatova, N. A. Schnaider, D. V. Dmitrenko, S. N. Zobova, I. E. Poverennova, A. V. Yakunina, V. A. Kalinin, S. K. Zyryanov, I. F. Tishchenkova
"... polymorphisms (SNPs) CYP2C9*3 (27.3%) versus those who had the common (wild-type) allele variant CYP2C9*1 ..."
 
Vol 10, No 4 (2018) Pharmacogenetics of schizophrenia in real clinical practice: a clinical case Abstract  similar documents
R. F. Nasyrova, N. A. Schnaider, K. O. Mironov, G. A. Shipulin, O. P. Dribnokhodova, E. A. Golosov, M. Yu. Tolmachev, B. V. Andreev, A. A. Kurylev, L. Sh. Akhmetova, О. V. Limankin, N. G. Neznanov
"... testing, she was found to be homozygous for the nonfunctional allelic variant CYP2D6*4 (1934 G>A, rs ..."
 
Vol 11, No 1 (2019) Antidepressant therapy in patients with cardiovascular diseases Abstract  similar documents
V. E. Medvedev, E. A. Korovyakova, V. I. Frolova, E. V. Gushanskaya
"... with their negative effect on the hepatic cytochrome CYP450 isoenzymes involved in the metabolism of various drugs ..."
 
Vol 8, No 3 (2016) Chemoreactome analysis of ethylmethylhydroxypyridine succinate Abstract  similar documents
O. A. Gromova, I. Yu. Torshin, L. E. Fedotova, A. N. Gromov
"... and the enzymes monoamine oxidase and cytochrome CYP1A1) distinguish EMHPS from the molecules of comparison ..."
 
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