Charles Bonnet syndrome: a clinical case and a review of literature
https://doi.org/10.14412/2074-2711-2018-2-83-87
Abstract
Charles Bonnet syndrome (CBS) includes the visual hallucinations in patients with decreased/lost vision in both eyes or hemianopsia, which are unassociated with cognitive dysfunction or confusion. The paper describes a clinical case of a 77-year-old woman who had daily complex mobile visual hallucinations occurring mainly in the early dawning with open eyes and in clear consciousness. The patient was referred to the vascular center with lacunar stroke detected by magnetic resonance imaging, which was asymptomatic and could not cause hallucinations. The latter appeared for the first time a year before stroke in the presence of a dramatic bilateral visual decrease caused by proliferative diabetic retinopathy. The hallucinations were regarded as a manifestation of the CBS. Adequate therapy led to their disappearance. The paper provides a review of current publications on the prevalence, causes, clinical presentations, and treatment of CBS.
About the Authors
V. N. GrigoryevaRussian Federation
Contact: Vera Naumovna Grigoryeva
18, Verkhne-Volzhskaya Embankment, Nizhny Novgorod 603950
T. N. Semenova
Russian Federation
18, Verkhne-Volzhskaya Embankment, Nizhny Novgorod 603950; 190, Rodionov St., Nizhny Novgorod 603126
E. A. Egorova
Russian Federation
190, Rodionov St., Nizhny Novgorod 603126
References
1. Pang L. Hallucinations Experienced by Visually Impaired: Charles Bonnet Syndrome. Optom Vis Sci. 2016 Dec;93(12):1466-1478. doi: 10.1097/OPX.0000000000000959
2. Madill SA, Ffytche DH. Charles Bonnet Syndrome in patients with glaucoma and good acuity. Br J Ophthalmol. 2005 Jun;89(6):785-6; author reply 786. doi: 10.1136/bjo.2005.066027/ 10.1136/bjo.2005.068510
3. Chokron S, Perez C, Peyrin C. Behavioral Consequences and Cortical Reorganization in Homonymous Hemianopia. Front Syst Neurosci. 2016 Jun 28;10:57. doi: 10.3389/fnsys.2016.00057. eCollection 2016.
4. Vale TC, Fernandes LC, Caramelli P. Charles Bonnet syndrome: characteristics of its visual hallucinations and differential diagnosis. Arq Neuropsiquiatr. 2014 May;72(5):333-6. doi: 10.1590/0004-282x20140015
5. Zakharov VV, Vakhnina NV, Parfenov VA. Cognitive disorders and their treatment in hypertension. Meditsinskii sovet. 2017;(1S):6-12. (In Russ.)].
6. O’Hare F, Bentley SA, Wu Z, et al. Charles Bonnet Syndrome in advanced retinitis pigmentosa. Ophthalmology. 2015 Sep;122(9):1951-3. doi: 10.1016/j.ophtha.2015.03.006. Epub 2015 Apr 11.
7. Tombini M, Pellegrino G, Zappasodi F, et al. Complex visual hallucinations after occipital extrastriate ischemic stroke. Cortex. 2012 Jun; 48(6):774-7. doi: 10.1016/j.cortex.2011.04.027. Epub 2011 May 6.
8. Sacks O. Hallucinations. New York: Knopf; 2012. 288 p.
9. Mü ri RM. Thalamic and brainstem regulatory systems – why disturbances external to the visual system can cause hallucinations. In: Collerton D, Mosimann U, Perry E, editors. The Neuroscience of Visual Hallucinations. Wiley-Blackwell: 2015. P. 255-80.
10. Diederich NJ, Goetz CG, Stebbins GT. The pathology of hallucinations: one or several points of processing breakdown? In: Collerton D, Mosimann U, Perry E, editors. The Neuroscience of Visual Hallucinations. Wiley-Blackwell: 2015. P. 281-306.
11. Gilmour G, Schreiber C, Ewing C. An examination of the relationship between low vision and Charles Bonnet Syndrome. Can J Ophthalmol. 2009 Feb;44(1):49-52. doi: 10.3129/i08-169.
12. Ffytche DH. Visual hallucinatory syndromes: past, present, and future. Dialogues Clin Neurosci. 2007;9(2):173-89.
13. Sarkar S, Subramanium E, Jha KN. Multimodal Hallucinations in a Visually Impaired Elderly Female: Is it a Variant of Charles Bonnet Syndrome? Indian J Psychol Med. 2017 May-Jun;39(3):366-368. doi: 10.4103/0253-7176.207331.
14. Cox TM, Ffytche DH. Negative outcome Charles Bonnet syndrome. Br J Ophthalmol. 2014 Sep;98(9):1236-9. doi: 10.1136/bjophthalmol-2014-304920. Epub 2014 May 13.
15. Onofrj M, Thomas A, Martinotti G, et al. The clinical associations of visual hallucinations. In: Collerton D, Mosimann U, Perry E, editors. The Neuroscience of Visual Hallucinations. Wiley-Blackwell: 2015. P. 91-118
16. Teeple RC, Caplan JP, Stern TA. Visual hallucinations: differential diagnosis and treatment. Prim Care Companion J Clin Psychiatry. 2009;11(1):26-32. doi: 10.4088/pcc. 08r00673
17. Hughes DF. Charles Bonnet Syndrome: a literature review into diagnostic criteria, treatment and implications for nursing practice. J Psychiatr Ment Health Nurs. 2013 Mar;20(2): 169-75. doi: 10.1111/j.1365-2850.2012.01904.x. Epub 2012 Mar 27.
18. Cohen SY, Safran AB, Tadayoni R, et al. Visual hallucinations immediately after macular photocoagulation. Am J Ophthalmol. 2000 Jun; 129(6):815-6. Doi: 10.1016/s0002-9394(00)00374-3.
Review
For citations:
Grigoryeva V.N., Semenova T.N., Egorova E.A. Charles Bonnet syndrome: a clinical case and a review of literature. Neurology, Neuropsychiatry, Psychosomatics. 2018;10(2):83-87. (In Russ.) https://doi.org/10.14412/2074-2711-2018-2-83-87