Mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes syndrome (MELAS): diagnostic criteria, features of epileptic seizures, and treatment approaches by the example of a clinical case
https://doi.org/10.14412/2074-2711-2017-4-65-69
Abstract
The paper describes a patient with mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes syndrome (MELAS). The features of the course and therapy of epilepsy in MELAS are discussed. The disease is known for its late diagnosis when years elapse from the onset of the clinical manifestations to diagnosis. The paper presents clinical criteria for the diagnosis of MELAS and the specific features of brain neuroimaging changes that allow identification of the disease at an early stage.
About the Authors
M. A. Yamin
Regional Consulting and Diagnostic Center
Russian Federation
127, Pushkinskaya St., Rostov-on-Don 344010
Russian Federation
127, Pushkinskaya St., Rostov-on-Don 344010
I. V. Chernikova
Rostov State Medical University, Ministry of Health of Russia
Russian Federation
Russian Federation
Department of Neurology and Neurosurgery with Courses of Manual Therapy and Reflexotherapy
29, Nakhichevansky Lane, Rostov-on-Don 344022
L. V. Araslanova
Regional Consulting and Diagnostic Center
Russian Federation
127, Pushkinskaya St., Rostov-on-Don 344010
Russian Federation
127, Pushkinskaya St., Rostov-on-Don 344010
P. A. Shevkun
Regional Consulting and Diagnostic Center
Russian Federation
127, Pushkinskaya St., Rostov-on-Don 344010
Russian Federation
127, Pushkinskaya St., Rostov-on-Don 344010
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Review
For citations:
Yamin MA, Chernikova IV, Araslanova LV, Shevkun PA. Mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes syndrome (MELAS): diagnostic criteria, features of epileptic seizures, and treatment approaches by the example of a clinical case. Nevrologiya, neiropsikhiatriya, psikhosomatika = Neurology, Neuropsychiatry, Psychosomatics. 2017;9(4):65-69. (In Russ.) https://doi.org/10.14412/2074-2711-2017-4-65-69
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