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Neurotrophic and antioxidant potential of neuropeptides and trace elements

https://doi.org/10.14412/2074-2711-2015-4-92-100

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Abstract

Neurotrophic therapy with brain extract-based drugs has been performed for decades. The basis for their neurotrophic activity is amino acids and neuropeptides. However, incomplete information on the composition of these drugs precludes a detailed description of mechanisms through which their pharmacological effects occur. The review considers the results of the most recent molecular pharmacological investigations and the mechanisms of therapeutic action of cerebrolysin.

About the Authors

O. A. Gromova
Ivanovo State Medical Academy, Ministry of Health of Russia; Russian Satellite Center of Trace Element Institute for UNESCO, N.I. Pirogov Russian National Medical Research University, Ministry of Health of Russia
Russian Federation

8, Sheremetevsky Passage., Ivanovo 153000;

1, Ostrovityanov St., Moscow 117997



A. V. Pronin
Ivanovo State Medical Academy, Ministry of Health of Russia
Russian Federation
8, Sheremetevsky Passage., Ivanovo 153000


I. Yu. Torshin
Russian Satellite Center of Trace Element Institute for UNESCO, N.I. Pirogov Russian National Medical Research University, Ministry of Health of Russia; Moscow Institute of Physics and Technology
Russian Federation

1, Ostrovityanov St., Moscow 117997;

9, Institutskiy Lane, Dolgoprudnyi, Moscow Region 141700



A. G. Kalacheva
Ivanovo State Medical Academy, Ministry of Health of Russia
Russian Federation
8, Sheremetevsky Passage., Ivanovo 153000


T. R. Grishina
Ivanovo State Medical Academy, Ministry of Health of Russia
Russian Federation
8, Sheremetevsky Passage., Ivanovo 153000


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Gromova O.A., Pronin A.V., Torshin I.Yu., Kalacheva A.G., Grishina T.R. Neurotrophic and antioxidant potential of neuropeptides and trace elements. Neurology, Neuropsychiatry, Psychosomatics. 2015;7(4):92-100. (In Russ.) https://doi.org/10.14412/2074-2711-2015-4-92-100

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