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Combination treatment for acute non-specific low back pain

https://doi.org/10.14412/2074-2711-2014-3-38-42

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Abstract

Spinal pain syndromes come to the forefront in the structure of referral rates for medical advice and considerably reduce quality of life in this category of patients. The paper considers the role of an edematous component in the development and chronization of pain. Occurring edema gives rise to local hemo- and lymphodynamic disorders, dysregulated vascular tone, activated thrombogenesis, and increased vascular permeability, eventually leading to the excessive irritation of nociceptors, the enhancement of a pain component, and the progression of tissue swelling.

Objective: to study the efficacy of L-lysine escinate in the combination treatment of acute non-specific low back pain.

Patients and methods. Sixty-two patients aged 21 to 53 patients (mean age 36.4±0.9 years) with acute low back pain were examined. L-lysine escinate having venotonic and anti-inflammatory activities was chosen as an agent to correct edema syndrome. The results of clinical, neurological, and manual muscular testing and assessment of the biomechanics of the vertebral column, obtained using the original soft package “Visual optic analysis” developed by the authors, were analyzed. All the patients were found to have acute non-specific low back pain or radiculopathy (entrapment syndrome) and considerable changes in the biomechanics of the vertebral column. The patients were treated in accordance with the standards of medical care for spinal pain. L-lysine escinate was additionally incorporated as an antiedema drug into the therapeutic
complex of the patients in the study group.

Results and discussion. The study patient group demonstrated a more pronounced trend towards reductions in pain syndrome and local muscle edema. It was noted that L-lysine escinate was effective in treating both acute pain syndromes and exacerbations of chronic low back pain and that additional non-drug programs should be included in order to correct an impaired motor stereotype.

About the Authors

A. E. Barulin
Volgograd State Medical University, Ministry of Health of Russia
Russian Federation

Volgograd, Russia 1, Pavshikh Bortsov Sq., Volgograd 400131



O. V. Kurushina
Volgograd State Medical University, Ministry of Health of Russia
Russian Federation
Volgograd, Russia 1, Pavshikh Bortsov Sq., Volgograd 400131


A. E. Puchkov
Volgograd State Medical University, Ministry of Health of Russia
Russian Federation
Volgograd, Russia 1, Pavshikh Bortsov Sq., Volgograd 400131


References

1. Бойко АН, Батышева ТТ, Костенко ЕВ и др. Нейродикловит: возможность применения у пациентов с болью в спине. Фарматека. 2010;(7):63–8. [Boiko AN, Batysheva TT, Kostenko EV, et al. Neurodiclovit: potential use in patients with dorsalgia. Farmateka. 2010;(7):63–8. (In Russ.)]

2. Курушина ОВ, Рыбак ВА, Барулин АЕ, Саранов АА. Психофизиологические аспекты формирования хронических болевых синдромов. Вестник Волгоградского государственного медицинского университета. 2010;(2):52–4. [Kurushina OV, Rybak VA, Barulin AE, Saranov AA. Psychophysiological aspects of development of chronic pain syndromes. Vestnik Volgogradskogo gosudarstvennogo meditsinskogo universiteta. 2010;(2):52–4. (In Russ.)]

3. Баранцевич Е, Андреев В. Возможности лечения хронической боли при пояснично-крестцовой радикулопатии. Врач. 2012;(11):13–9. [Barantsevich E, Andreev V. Possibilities of treating chronic pain in lumbosacral radiculopathy. Vrach. 2012;(11):13–9. (In Russ.)]

4. Барулин АЕ, Курушина ОВ. Боль в спине: гендерные особенности. Саратовский научно-медицинский журнал. 2012;8(2):477–81. [Barulin AE, Kurushina OV. Back pain: gender features. Saratovskii nauchno-meditsinskii zhurnal. 2012;8(2):477–81. (In Russ.)]

5. Стратегия профилактики и контроля неинфекционных заболеваний и травматизма в Российской Федерации (проект), Москва, 2008. Профилактика заболеваний и укрепление здоровья. 2008;(4):9–19. [The strategy of prevention and control of non-communicable diseases and traumatismin the Russian Federation (a draft), Moscow, 2008. Profilaktika zabolevaniy i ukreplenie zdorovya. 2008;(4):9–19. (In Russ.)]

6. Кузьмичев А.Я. Кровообращение при компрессии спинного мозга и его корешков. Автореф. дис. … докт. мед. наук. Ленинград; 1971. [Kuz'michev A.Ya. Krovoobrashchenie pri kompressii spinnogo mozga i ego koreshkov: Avtoref. dis. … dokt. med. nauk [Blood circulation at a compression of a spinal cord and its backs: Dr. Diss. (Med. Sci.)] Leningrad; 1971.]

7. Скоромец AA, Тиссен ТП, Панюшкин АИ, Скоромец ТА. Сосудистые заболевания спинного мозга. Санкт-Петербург: Сотис; 1998. 527 с. [Skoromets AA, Tissen TP, Panyushkin AI, Skoromets TA. Sosudistye zabolevaniya spinnogo mozga [Vascular diseases of a spinal cord]. St- Petersburg: Sotis; 1998. 527 p.]

8. Скоромец AA, Скоромец АП, Скоромец ТА, Тиссен ТП. Спинальная ангионеврология. Москва: Медпрес-информ; 2003. 608 с. [Skoromets AA, Skoromets AP, Skoromets TA, Tissen TP. Spinal'naya angionevrologiya [Spinal angionevrologiya]. Moscow: Medpres-inform; 2003. 608 p.]

9. Рыбачук ОИ, Калашников АВ. Применение L-лизина эсцината для лечения больных в клинике травматологии и ортопедии. Вестник ортопедии, травматологии и протезирования. 2001;(3):65–7. [Rybachuk OI, Kalashnikov AV. L-lysine escinate application for treatment of patients in traumatology and orthopedics clinic. Vestnik ortopedii, travmatologii i protezirovaniya. 2001;(3):65–7. (In Russ.)]

10. Третьякова ЕА, Каракулова ЮВ. Клинико-биохимическое исследование механизмов формирования хронических болей в нижней части спины. Журнал неврологии и психиатрии им. С.С. Корсакова. 2011;111(9):58–60. [Tret'yakova EA, Karakulova YuV. Clinical and biochemical mechanisms of the formation of chronic low back pain. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. 2011;111(9):58–60. (In Russ.)]


For citation:


Barulin A.E., Kurushina O.V., Puchkov A.E. Combination treatment for acute non-specific low back pain. Neurology, Neuropsychiatry, Psychosomatics. 2014;6(3):38-42. (In Russ.) https://doi.org/10.14412/2074-2711-2014-3-38-42

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ISSN 2074-2711 (Print)
ISSN 2310-1342 (Online)