Preview

Neurology, Neuropsychiatry, Psychosomatics

Advanced search

Depression in Parkinson's disease

https://doi.org/10.14412/2074-2711-2010-110

Full Text:

Abstract

Parkinson's disease (PD) is a multisystemic neurodegenerative disease with a wide spectrum of not only motor, but also neuropsychic disorders. Depression occurs in an average of 40-50% of patients and it is one of the leading factors that decrease their quality of life. The paper gives the present views of the clinical presentation and pathogenesis of depression, and approaches to its therapy in PD.

References

1. <div><p>Яхно Н.Н., Захаров В.В., Нодель М.Р. Когнитивные и другие нервно-психические нарушения при болезни Паркинсона. В кн.: Болезни движений: медицинские и социальные аспекты. Под ред. Е.И. Гусева, А.Б. Гехт. М., 2010;с.95-7.</p><p>Нодель М.Р., Яхно Н.Н. Нервно-психические нарушения при болезни Паркинсона. Неврол нейропсихиатр психосом 2009;2:3-8.</p><p>Aarsland D., Marsh L., Schrag A. Neuropsychiatric symptoms in Parkinsons Disease. Mov Dis 2009;24(15):2175-86.</p><p>Goetz C.G. New developments in depression, anxiety, compulsiveness, and hallucinations in Parkinsons Disease. Mov Dis 2010;25:104-9.</p><p>O'Sullivan S.S., Williams D.R., Gallarher D.A. et al. Non motor symptoms as presenting complaints in Parkinsons disease: a clinicopathological study. Mov Dis 2008;23:101-6.</p><p>Вознесенская Т.Г. Некогнитивные нервно-психические нарушения при когнитивных нарушениях в пожилом возрасте. Неврол журн 2010;3:4-18.</p><p>Мирецкая А.В., Федорова Н.В., Макаров В.В. Депрессивные расстройства у больных болезнью Паркинсона. Болезнь Паркинсона и расстройства движений. Рук-во для врачей (по материалам I Национального конгресса). М., 22-23 сентября 2008;97-9.</p><p>Shrag A., Jahanshahi M., Quinn N.P. What contributes to quality life in patients with Parkinsons disease? J Neurol Neurosurg Neuropsych 2000;69:308-12.</p><p>Scaravilli T., Gasparoli E., Rinaldi F. et.al. Health related quality of life in Parkinsons disease. J Neurol Neurosurg Psychiat 2003;74(2):163-9.</p><p>Mc Kinlay A., Grace R.C., Dalrymple-Alford J.C. et al. A profile of neuropsychiatric problems and their relationship to quality of life for Parkinsons disease. Park Relat Dis 2008;14:37-42.</p><p>Cole S.A., Woodard J.L., Juncos J.L. et al. Depression and disability in Parkinsons disease. J Neuropsychiatry Clin Neurosci 1996;8:20-5.</p><p>Shrag A., Jahanshahi M., Quinn N.P. What contributes to depression in Parkinsons disease? Psychol Med 2001;31:65-73.</p><p>Starkstein S.E., Preziosi T.J., Robinson R.G. Sleep disorders, pain and Parkinsons disease depression in Parkinsons disease. Eur Neurol 1991;31(6):352-5.</p><p>Norman S., Troster A.I., Fields J.A. et al. Effects of depression and Parkinsons disease on cognitive functioning. J Neuropsychiatr Clin Neurosci 2002;14(1):31-6.</p><p>Dooneief G., Mirabello E., Bell K. et al. An estimate of the incidence of depression in idiopathic Parkinsons disease. Arch Neurol 1992;49(3):305-7.</p><p>Lemke M.R. Depressive symptoms in Parkinsons disease. Eur J Neurol 2008;15(Suppl. 1):21-5.</p><p>Gotham A.M., Brown R.C., Marsden C.D. Depression in Parkinsons disease: a quantitative and qualitative analysis in Parkinsons disease. J Neuropsychiatry Clin Neurosci 1996;8:20-5.</p><p>Mayberg H.S., Starkstein S.E., Sadzot B. et al. Selective hypometaboloism in the inferior frontal lobe in depressed patients with Parkinsons Disease. Ann Neurol 1990;28(1):57-64.</p><p>Matsiu H., Nishinaka K., Oda M. et al. Depression in Parkinsons disease:diffusion tensor imaging study. J Neurol 2007;254:1170-3.</p><p>Malhi G.S., Berk M. Does dopamine dysfunction drive depression? Acta Psychiatr Scand Suppl 2007;433:116-24.</p><p>Chaudhuri K.R., Schapira A.H.V. Non-motor symptoms of Parkinsons disease: dopaminergic pathophysiology and treatment. Lancet Neurol 2009;8:464-74.</p><p>Braak H., Del Tredici K., Rub U. et al. Staging of brain pathology related to sporadic Parkinsons disease. Neurology Aging 2003;24:197-210.</p><p>Mayeux R., Stern Y., Cote I. et al. Altered serotonin metabolism in depressed patients with Parkinsons Disease. Neurol 1984;34(5):642-6.</p><p>Yamomoto M. Depression in Parkinsons Disease: its prevalence, diagnosis, and neurochemical background. J Neurol 2001;248(Suppl. 3):5-11.</p><p>Kuhn W., Muller T., Gerlach M. et al. Depression in Parkinsons Disease: biogenic amines in CSF of de novo patients. J Neural Transm 1996;103(12):1441-5.</p><p>Frisina P.G., Haroutunian V., Libow L.S. The neuropathological basis for depression in Parkinsons Disease. Park Relat Dis 2009;15:144-8.</p><p>Remy P., Doder M. Lees A. et al. Depression in Parkinsons Disease: loss of dopamine and noradrenaline innervation in the limbic system. Brain 2005;128:1314-22.</p><p>Guttman M., Torti M., Warsh J. et al. Are brain serotonin transporter levels decreased in depressed patients with Parkinsons Disease? J Neurol Sci 2006;248:99.</p><p>Alex K.D., Pehek E.A. Pharmacologic mechanisms of serotoninergic regulation of dopamine neurotransmission. Pharmacol Ther 2007;113:296-320.</p><p>Santamaria J., Tolosa E., Valles A. Parkinsons disease with depression: a possible subgroup of idiopathic parkinsonism. Neurology 1986;36:1130-3.</p><p>Leentjens A.F., Lousberg R., Verhey F.R. Markers for depression in Parkinsons Disease. Acta Psych Scand 2002;106(3):196-201.</p><p>Cummings J.L. Depression and Parkinsons disease: a review. Am J Psychiatry 1992;149:443-54.</p><p>Tanberg E., Larsen J.P., Aarsland D. et al. Risk factors for depression in Parkinsons Disease. Arch Neurol 1997;54(5):625-30.</p><p>Rojo A., Agullar M., Garolera M.T. et al. Depression and Parkinsons disease: clinical correlates and outcome. Park Relat Dis 2003;10(1):23-8.</p><p>Cole S.A., Woodard J.L., Juncos J.L. et al. Depression and disability in Parkinsons disease. J Neuropsychiatry Clin Neurosci 1996;8(1):20-5.</p><p>Arabia G., Grossardt B.R., Geda Y.E. et al. Increased risk of depressive and anxiety disorders in relatives of patients with Parkinsons disease. Arch Gen Psych 2007;64:1385-92.</p><p>Янакаева Т.А. Сравнительный анализ когнитивных и аффективных расстройств при дисциркуляторной энцефалопатии, болезни Паркинсона и болезни Альцгеймера. Дис. ... канд. мед. наук. М., 1999.</p><p>Starkstein S.E., Petracca G., Chemerinski E. et al. Depression in classic versus akinetic-rigid Parkinsons disease. J Neur Ment Dis 1998;13(1):29-33</p><p>Смоленцева И.Г., Левин О.С., Иванов А.Ю. Немоторные флюктуации при болезни Паркинсона. Болезнь Паркинсона и расстройства движений. Рук-во для врачей (по материалам I Национального конгресса). М., 22-23 сентября 2008;108-11.</p><p>Liebermann F. Depression in Parkinsons Disease - a review. Acta Neurol Scand 2006;113:1-8.</p><p>Lemke M.R. Depressive symptoms in Parkinsons disease. Eur J Neurol 2008;15(Suppl. 1):21-5.</p><p>American Psychiatric Association. Diagnostic and Statistical Manual of mental Disorders, 4th ed. Washington, DC: APA Press, 2000.</p><p>Starkstein S.E., Merello M., Jorge R. et al. A validity study of depressive syndromes in Parkinsons disease. Mov Dis 2008;23:538-46.</p><p>Inoue T., Kitagawa M., Tanaka T. et al. Depression and major depressive disorder in patients with Parkinsons disease. Mov Dis 2010;25(1):44-9.</p><p>Barone P., Antonini A., Colosimo C. et al. The PRIAMO study: a multicenter assessment of nonmotot symptoms and their impact on quality of life in Parkinson disease. Mov Dis 2009;9:215-6.</p><p>Shrag A., Barone P., Brown R.G. et al. Depression rating scales in Parkinson disease: critique and recommendations. Mov Dis 2007;22:1077-192.</p><p>Starkstein S.E., Mayberg H.S., Preziosi T.J. et al. Reliability, validity, and clinical correlates of apathy in Parkinsons disease. J Neuropsychiatry Clin Neurosci 1992;4:134-7.</p><p>Dujardin K., Sockeel P., Devos D. et al. Characteristic of apathy in Parkinsons disease. Mov Dis 2007;22:778-84.</p><p>Pedersen K.F., Larsen J.P., Alves G. et al. Prevalence and clinical correlates of apathy in Parkinsons disease: a community-based study. Park Relat Dis 2009;15:295-9.</p><p>Hilten J.J., van Hoogland G., Velde E.A. Diurnal effects of motor activity and fatigue in Parkinsons disease. J Neurol Neurosurg Psychiatr 1993;56:874-7.</p><p>Weintraub D., Morales K.H., Moberg P.J. et al. Antidepressant studies in Parkinsons disease: a review and meta-analysis. Mov Dis 2005;20:1161-9.</p><p>Miyasaki J.M., Shannon K., Voon V. et al. Practice parameter: evaluation and treatment of depression, psychosis and dementia in Parkinsons disease (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurol 2006;66:996-1002.</p><p>Devos D., Dujardin K., Poirot I. et al. Comparison of desipramine and citalopram treatments with depression in Parkinsons disease: a double-blind placebo-controlled study. Mov Dis 2008;23:850-7.</p><p>Menza M., Dobkin R.D., Marin H. et al. A controlled trial of antidepressants in patients with and depression. Neurol 2009;72:886-92.</p><p>Lemke M.R., Raethjen J. Depression and Parkinson disease-pathophysiology, diagnosis, treatment. Ed. Lemke M.R. Bremen: UNI-MED, 2007;70.</p><p>Mann J.J., Kapur S. A dopaminergic hypothesis of major depression. Clin Neuropharmacol 1996;18(Suppl. 1):57-65.</p><p>Barbeu A.L. L-Dopa therapy in Parkinson disease: a critical review of nine years experience. J Can Med Assoc 1969;101:791-800.</p><p>Barone P., Poewe W., Tolosa E. et al. Efficacy of double-blind, placebo-controlled pramipexole against depression in Parkinsons disease. Abstracts of the Movement Disorders Societys Thirteenth International Congress of Parkinson's disease and movement disorders 2009 June 7-11 (Suppl. 1):291.</p><p>Нодель М.Р., Артемьев Д.В., Яхно Н.Н. Эффективность дофаминового агониста Мирапекса при болезни Паркинсона. Неврол журн 1999;6:45-9.</p><p>Lemke M.P., Brecht H.M., Koester J.K. et al. Anhedonia, depression, and motor functioning in Parkinsons disease during treatment with Pramipexole. J Neuropsych Clin Neurosci 2005;17(2):214-20.</p><p>Schoenfeld M.A., Pantelie C.M., Schwartz B. Clinical criteria for the switch of treatment strategies in Parkinson's disease. Clinical Neurol and Neurosurg 2003;105:241-4.</p></div><br />


For citation:


Nodel' M.R., Nodel M.R. Depression in Parkinson's disease. Neurology, Neuropsychiatry, Psychosomatics. 2010;2(4):11-17. (In Russ.) https://doi.org/10.14412/2074-2711-2010-110

Views: 761


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2074-2711 (Print)
ISSN 2310-1342 (Online)