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Drug-resistant epilepsy associated with cortical dysplasias

https://doi.org/10.14412/2074-2711-2013-2481

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Abstract

Epilepsy associated with malformations of the cerebral cortex is reported in the literature to account for up to 25% of the total cases of symptomatic epilepsies. It is characterized by the most severe course and often induces drug-resistance in seizures. A group of patients with resistant seizures is singled out among the total number of patients with symptomatic epilepsy caused by cerebral cortical dysgenesis. The most important risk factors for resistance are identified in dysplasias. The prognostically unfavorable clinical features of epilepsy are described. A diagnostic algorithm is proposed to identify risk groups and to prevent drug-resistant forms of epilepsy.

About the Authors

I. E. Poverennova
Department of Neurology and Neurosurgery, Samara State Medical University, Ministry of Health of Russia, Samara
Russian Federation


T. V. Kuznetsova
Department of Neurology and Neurosurgery, Samara State Medical University, Ministry of Health of Russia, Samara
Russian Federation


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For citation:


Poverennova I.E., Kuznetsova T.V. Drug-resistant epilepsy associated with cortical dysplasias. Neurology, Neuropsychiatry, Psychosomatics. 2013;5(1S):7-11. (In Russ.) https://doi.org/10.14412/2074-2711-2013-2481

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ISSN 2074-2711 (Print)
ISSN 2310-1342 (Online)